West Ham United marked their first match at the Olympic Stadium with a 3-0 win over Slovenian side NK Domzale, Cheikhou Kouyate scoring twice to help secure a place in the Europa League playoff round.
Striker Glenn Murray scored a brace and Jose Izquierdo curled in a shot from outside the box to lift promoted Brighton to 10th in the standings, leaving West Ham in 17th just above the relegation zone.
Brief reports of English Premier League matches on Saturday:
Check out the 10 most expensive transfers in British soccer history.
Roy Hodgson has given himself the option to give England a youthful, fresh edge at the World Cup after including Ross Barkley, Raheem Sterling, Alex Oxlade-Chamberlain, Luke Shaw and Adam Lallana in his provisional squad on Monday. There were no real surprises as the irresistible late-season form of Everton's attacking midfielder Barkley and Liverpool wide man Sterling made their inclusion an easy choice for Hodgson despite having only five caps between them.
Arsenal's victory was scrappy and nervy but Laurent Koscielny's 72nd-minute winner was enough to move them two points clear at the summit after LeicesterCity's surprise push faltered with a goalless draw at home to 10-man Bournemouth.
News of all that's transpired on and off the football field
Manchester City shook off the impact of a COVID outbreak in their ranks to outclass Chelsea 3-1 at Stamford Bridge
Alexis Sanchez grabbed a 15-minute hat-trick as Arsenal shook off any hangover from their midweek League Cup defeat to thrash West Ham United 5-1 and climb to second in the English Premier League.
Five talking points from the Premier League weekend:
Manchester City opened up a two-point lead over their neighbours Manchester United at the top of the English Premier League on Saturday thanks to another display of scintillating brilliance in a 7-2 thrashing of Stoke City at the Etihad Stadium.
Former Real youth player Joselu pulled a goal back for Alaves in the 59th minute, powering in a header from a free kick, but Benzema rounded off the victory for second-placed Real with an exquisite solo run and goal in the 70th minute.
Images from Sunday's action in the Premier League.
Manchester City are about to find out whether Raheem Sterling has the ability to justify his enormous price tag or is just another over-rated young English footballer motivated purely by his bank balance.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
West Ham United players are motivated by their position in the Premier League table and they are keen to stay close to the top for as long as possible, manager Slaven Bilic said on Thursday.
Chelsea's terrible start to the season plumbed new depths on Saturday when the Premier League champions lost 2-1 at West Ham United.
Chelsea brushed aside London rivals West Ham United with a 2-1 away win that restored their 10-point lead at the top of the Premier League on Monday.
Images from EPL matches played on Tuesday
Arsenal, who fired Unai Emery as manager last week and appointed former player Freddie Ljungberg as caretaker boss, now sit 10th in the table on 19 points, with Brighton a single point behind and three places below them.
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Adrian fired past opposite number and Spanish compatriot Joel Robles immediately after the Everton keeper had crashed his spot kick against the crossbar as West Ham won 9-8 on penalties.
Leaders Manchester City kept up their unbeaten run with a 3-1 win over Bournemouth on Saturday. Manchester United salvaged a 2-2 draw at Southampton, who sacked manager Mark Hughes on Monday.
Manchester United ended a momentous evening hinting at a brighter future after reaching the semi-finals with a 2-1 victory.
IMAGES from the English Premier League matches played on Saturday.
Images from the FA Cup matches played on Saturday
Arsenal beat Brighton and Hove Albion 3-2 to reach the FA Cup fifth round.
Manchester City made Raheem Sterling the most expensive English player in history when they completed a deal for the 20-year-old forward on Tuesday, rubber-stamping an acrimonious end to his Liverpool career.
Watford climbed into the top four of the Premier League after Tom Cleverley's 92nd-minute goal gave them a 2-1 victory over Arsenal at Vicarage Road on Saturday.
Barcelona's lead at the top of La Liga was cut after a second consecutive defeat and LeicesterCity's improbable march towards the Premier League title showed no sign of slowing as they won a fifth straight match. Juventus stayed six points clear of Napoli after Italy's top two both won and Bayern Munich extended their Bundesliga lead to seven points. Here is a summary of results from football matches played across Europe over the weekend.
Images from the English Premier League matches played on Wednesday.
Aston Villa beat Crystal Palace 1-0 to win a Premier League match for the first time since August while a late goal from Paul Dummett earned a 3-3 draw for Newcastle United against Manchester United on Tuesday.
Chelsea overpowered West Ham United and Manchester City outclassed West Bromwich Albion as the Premier League title rivals signalled their intent at the start of a hectic holiday programme on Friday.
Bitter rivals Arsene Wenger and Jose Mourinho had wildly contrasting afternoons on Saturday as Arsenal went top of the Premier League and champions Chelsea lost again with their manager being sent off.
Dimitri Payet struck a brace for the Hammers against a tired Newcastle, whose players had to trudge the last mile to West Ham United's stadium after their team coach became stuck in London's rush-hour traffic before Monday's Premier League fixture.
Cesc Fabregas and Branislav Ivanovic struck late goals to earn improving champions Chelsea a 2-1 victory at Southampton in the Premier League on Saturday.
Arsenal ended their away hoodoo against Premier League title challengers with a 2-0 victory at Manchester City on Sunday that left Chelsea five points clear at the top.
Chelsea and Manchester City tightened their stranglehold on the Premier League title race on Saturday, recording victories over struggling clubs to stretch further clear of their increasingly forlorn pursuers.
Mauricio Pochettino's Tottenham Hotspur can cement their status as the top dogs in the capital if they end an eight-year wait and defeat Arsenal in the North London derby on Sunday.
Injuries have blighted Liverpool's start but Adam Lallana is back in full training after damaging his thigh pre-season and is expected to feature while another injury concern, Sadio Mane, also trained on Wednesday after tweaking a hamstring on international duty with Senegal.
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