Alexis Sanchez had equalised for the visitors, scoring on the rebound after Manuel Neuer saved his 30th-minute penalty but the Gunners suffered when captain Laurent Koscielny limped off injured to leave the defence exposed.
Manchester City went 11 points clear with a record 14th consecutive Premier League win in an entertaining derby against Manchester United at Old Trafford.
Another unconvincing display from Manchester United was compounded by a needless red card for Angel Di Maria.
'Generations of football fans will eternally be grateful to Johan Cruyff and what he did for the beautiful game,' says Aabhas Sharma.
Images from the English Premier League matches played at Old Trafford on Saturday
Metalist Kharkiv, due to play Schalke 04 in the Champions League play-off round next week, has been kicked out of the competition over a domestic match-fixing case dating back to 2008, the UEFA said on Wednesday. The decision by UEFA's appeals committee came 10 days after Metalist lost an appeal at the Court of Arbitration for Sport.
Aston Villa were crushed 6-1 by Southampton but joined Leicester City in celebrating Premier League survival on Saturday while Steven Gerrard's farewell party was spoiled as Liverpool lost 3-1 to Crystal Palace.
Arsenal manager Arsene Wenger slammed his side's defending after watching Anderlecht claw their way back from three goals down to earn a 3-3 draw in Champions League Group D on Tuesday.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
News of all that's transpired on and off the football field
Swansea City came from behind to beat Arsenal 2-1 and Tottenham Hotspur's misery continued with a 2-1 home defeat by Stoke City, making it a nightmare Sunday for north London.
James Milner, set to win his 50th England cap against San Marino on Thursday, believes his international captain Wayne Rooney has a good chance of reaching another significant landmark in the coming days.
Photos from the UEFA Champions League last 16 first leg-matches played on Wednesday
'Keep Calm And Carry On' could be Claudio Ranieri's motto for the second half of the season after Leicester City earned a 1-0 win at Tottenham Hotspur on Wednesday to put the heat back on Premier League leaders Arsenal.
'I think it's unacceptable what he does to Koscielny. He pushes him down, he hits him in the face. I do not understand Mike Dean's decision at all. Why does Diego Costa stay on the pitch and Gabriel is sent off?' 'If you want to speak about Diego Costa with me, it's just to say he played like he has to play and that's why you have full stadiums, you sell to television around the world for millions and millions because the game has to be played like that'
A summary of sports events and sports persons, who made news on Tuesday
News of all that's transpired on and off the football field
Manchester United won away for the first time this season when they beat Arsenal 2-1 at the Emirates Stadium on Saturday to climb to fourth in the Premier League table.
Arsenal and Manchester City meet at The Emirates on Saturday when both teams will seek to roar into life after making spluttering starts to their Premier League campaigns.
Jose Mourinho got the better of old adversary Arsene Wenger once again as Chelsea showed their strength-in-depth by reaching the League Cup quarter-finals with a 2-0 win over London rivals Arsenal on Tuesday.
Saudi club Al-Hilal have furiously demanded a formal probe into the appointment of the referees for the Asian Champions League final, which they lost 1-0 on aggregate to Australia's Western Sydney Wanderers last weekend.
Real Madrid earned their first-ever win over Liverpool with a wondrous Cristiano Ronaldo goal spearheading a 3-0 Champions League victory at Anfield on Wednesday which appeared as classy as it was dominant.
Barcelona battled back from a goal down and scored twice in the second half to overcome hosts Borussia Moenchengladbach 2-1 in their Champions League Group C match on Wednesday despite the absence of the injured Lionel Messi.