Djokovic is clubbed with Federer, Juan Martin Del Potro, David Goffin and Alexander Zverev.
The manner of her defeat inevitably led to speculation that the 37-year-old may have had a physical problem that stopped her from competing with the effectiveness she had shown in earlier rounds.
The 'Big Four' of men's tennis have made it into the second week of Wimbledon unscathed and largely untroubled while the women's draw remains wide open, but "Manic Monday" could offer major clues as to the destination of this year's titles.
'Maria will look at it and see no one dominant. Serena Williams is the only player in the past who has been like a thorn in her side, but she feels mentally superior to most of the other and she feels she can win against them all'
Kristina Mladenovic took her love affair with Roland Garros to a new level on Friday.
List of Wimbledon women's singles champions:
World No 1 Novak Djokovic will face Argentina's Juan Martin del Potro, the player who denied him a medal in London, in the opening round of the Rio Olympics after the draw was made on Thursday.
Britain's Andy Murray, bristling with confidence after ending a three-year wait for another Grand Slam title at Wimbledon, will seek to make history in Brazil by becoming the first man to win successive Olympic gold medals in men's singles tennis.
Serena Williams thrashed unseeded Russian Elena Vesnina 6-2, 6-0 to reach a ninth Wimbledon final on Thursday.
Serena Williams gave little away on Sunday as she assessed her chances of retaining her Wimbledon title -- and dismissed suggestions that she is under any pressure. The 34-year-old American has not struck a ball competitively since losing to Spain's Garbine Muguruza in the French Open final on June 4 - a defeat that frustrated her hopes of matching Steffi Graf's professional era record of 22 grand slam titles. Considering she also fell at the final hurdle in Australia against Angelique Kerber and went out of the U.S. Open semi-finals last year when two wins away from a calendar grand slam, Williams would be forgiven for feeling a little edgy.
Seeing world number 50 Mischa Zverev and wildcard Denis Istomin upset the top two players in the world at Melbourne Park shows more players believe they can take shake up the established order and that can only be good for tennis, says Roger Federer.
Zverev defeated Anderson 6-4, 6-4 and captured his fourth title of the year in the finals played on Sunday.
Zverev, who is looking for his fourth tournament win of the year, needed only 64 minutes to defeat Nishikori and move into the final in WashingtonDC where he will play Kevin Anderson after the South African beat Jack Sock by the same score.
PHOTOS from day four of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Saturday
Former world number one Andy Murray won his first ATP tour singles match in nearly nine months with a 6-3, 6-7(6), 6-1 victory over American Tennys Sandgren in the opening round of the Zhuhai Championships.
Venus Williams ended Johanna Konta's fairy tale run 6-4, 6-2 to reach her first Wimbledon singles final since 2009.
Former world number one Garbine Muguruza was beaten 7-5, 6-4 by Aryna Sabalenka in the China Open second round on Tuesday while an ailing Jelena Ostapenko lost 6-0, 6-0 to Wang Qiang.
Garbine Muguruza's preparations for next week's Australian Open were thrown into disarray when the world number three pulled out of the Sydney International with a thigh injury on Wednesday.
Williams had little trouble against the 31-year-old German although the gusty breezes at Auckland Tennis Centre played havoc with her ball toss, especially when she was serving for the match at 5-3 in the second set.
Prajnesh, India's top-ranked singles player at 122, downed the local wild card Jason Kubler 7-5, 6-3 in the first round
Images from Monday's action at the French Open.
Halep became the first Romanian to reach the summit of the women's rankings when she beat French Open champion Jelena Ostapenko in the semi-finals of the China Open in Beijing, a feat she feels is the high point of her career to date.
Roger Federer took 55 minutes to dispel all injury doubts with a 6-2, 6-1 routing of unheralded German Tobias Kamke in the second round of the Brisbane International on Thursday. Media speculations swirled around the fitness of the world number three less than two weeks before he launches his bid for a fifth Australian Open title and the Swiss maestro dismissed them by dropping only three games in a lop-sided contest. "I'm going to do my best to stay injury free and give myself a chance to win another grand slam," Federer said after setting up a quarter-final against Grigor Dimitrov.
The Romanian broke Williams's serve in the first game but that was the only one she managed for the rest of the opening set as the American bulldozed her way through the set in 20 minutes, serving it out with an ace.
US tennis powerhouse Serena Williams dispatched France's Alize Cornet in two sets on Monday, ending a streak of weak family performances that saw older sister Venus eliminated from singles on Saturday and the pair knocked out in doubles on Sunday.
Newly-crowned French Open champion Simon Halep said she was inspired to win her first Grand Slam title by her manager Virginia Ruzici's feats 40 years ago at Roland Garros.
Top seed Serena Williams and her older sister Venus led a foursome of American women into the Australian Open fourth round on Saturday.
As a new and unique brand of tennis makes its debut in the country with a mix of Indian and international stars, veteran Leander Paes says the Champions Tennis League, for him, is about building bonds and new friendships.
Wimbledon champion Garbine Muguruza notched up her first ever victory on Arthur Ashe Stadium with a 6-0, 6-3 win over American Varvara Lepchenko at the US Open on Monday.
Novak Djokovic and Andy Murray will face off in a second claycourt final within eight days at the Italian Open after the two in-form players proved on Saturday that they will be the ones to beat at the season's second Grand Slam in Roland Garros.
Serena Williams allowed herself a few moments to enjoy her sixth Wimbledon title before thoughts turned to New York and the elusive calendar year feat.
The daughter of two lawyers and a former waitress received their last orders at the Wimbledon on Tuesday when Madison Keys and Timea Bacsinszky missed out on a great opportunity to set up a semi-final date.
American teenager Amanda Anisimova, fresh off an impressive run at Indian Wells, beat China's Wang Qiang 6-3, 1-6, 6-2 at the Miami Open on Tuesday to set up a second round clash with Spanish third seed Garbine Muguruza.
'If I was a lady player, I'd go down every night on my knees and thank God that Roger Federer and Rafael Nadal were born.'
The latest tennis rankings have been announced by the ATP and WTA
IMAGES from matches played at the Miami Masters in Key Biscayne, Florida
Images from Day 4 of the French Open matches played at Roland Garros in Paris on Wednesday
With not one, or two but three passports in her possession, Britain's Johanna Konta could have been forgiven for suffering an identity crisis.
Defending champion Djokovic fired his 15th ace on match point to defeat Querrey but his serve had been an issue earlier in their second-round encounter.
Rafael Nadal withdrew from the Indian Wells tournament on Saturday with a knee injury, shortly before his eagerly-awaited semi-final clash with great rival Roger Federer.