Arsenal's Premier League title prospects were enhanced without them even kicking a ball on Wednesday as their closest challengers Manchester City and Aston Villa both dropped points.
Aston Villa and Chelsea drop crucial points in the Premier League as Leeds and Burnley earn draws; James Milner sets appearance record.
AS Roma took a big step towards qualifying for the Europa League last 16 with a 2-0 win over VfB Stuttgart on Thursday.
Striker Morgan Rogers netted a double as Aston Villa fought back from a halftime deficit to beat Leeds United 2-1 away.
A round-up of Saturday's action in the English Premier League.
IMAGES from the UEFA Champions League matches played on Wednesday
Aston Villa became the latest of the Premier League's top-four challengers to miss an opportunity when they were held to a disappointing goalless draw by West Ham United on Sunday.
Kevin de Bruyne struck twice to inspire Manchester City to a dominant 4-2 win at Crystal Palace on Saturday and move the champions level on points with Liverpool at the top of the Premier League table.
Tottenham Hotspur's bid to break up the Premier League's big-four cartel suffered a hefty setback on Saturday when they lost 1-0 at home to Stoke City courtesy of an 86th-minute goal by Glenn Whelan.
Bukayo Saka scored either side of halftime as Arsenal crushed second-bottom Burnley 5-0.
Leicester City's veteran striker Jamie Vardy came off the bench to break his long scoring drought and earn his side a 1-1 draw with a late equaliser
Images from Saturday's action in the Premier League.
Aston Villa will meet holders Arsenal in the FA Cup final next month.