Saturday's EPL meeting is crucial as champions United were beaten home and away by West Ham last year.
West Ham United were fined for breaching ownership rules over signings of Carlos Tevez and Javier Mascherano.
Manchester United must beat Middlesbrough today to re-open a six points lead over Chelsea in the English Premier League.
Wayne Rooney steered Manchester United to a 2-0 victory over Sheffield United that sent them six points clear at the top of the Premier League on Tuesday.
The 28-year-old France international collided with Tomkins in the 76th minute at the Emirates and appeared to be dazed by the clash, but was left on the pitch after being assessed by his team's medical staff.
West Ham United defender George McCartney scored his first club goal in over seven years on Sunday but Kevin Nolan made it 1-1 in injury time to snatch a Premier League point for struggling Bolton Wanderers.
News of all that transpired on and off the football field.
Hooliganism is not a problem in English football, according to Arsenal manager Arsene Wenger, despite a week in which disturbances at West Ham United's League Cup tie against Chelsea tarnished the game's glossy image.
Three months after the last ball was kicked, the Premier League emerges from the shadow of the COVID-19 pandemic this week for what will be a 92-match slog to the finish.
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
The Arsenal manager was also warned to his future conduct following his touchline bust-up with former West Ham United manger Alan Pardew last month.
A stunning 87th-minute free kick by captain Steven Gerrard gave Liverpool a 2-1 victory at Aston Villa as the new Premier League season opened on Saturday.
The strip made a memorable debut in the 7-0 thrashing of Maribor in the Champions League group stage, marking Liverpool's biggest ever away win in European competition.
Fabinho's first-half goal earned Liverpool a 1-0 win at Burnley
Manchester United manager Alex Ferguson said he would wait for as long as it takes to sign Argentine forward Carlos Tevez.
Substitute Marlon Harewood struck two minutes from time to hand West Ham United a 1-0 win over Arsenal at Upton Park on Sunday.
The omens are good for a Chelsea side heading into Christmas top of the Premier League tree but manager Jose Mourinho does not want to give title rivals Manchester City any reason to cheer over the festive season. Check out the big games on Boxing Day.
The 27-year-old Wales captain signed a five-year deal.
The Tottenham Hotspur striker was at the centre of controversy after admitting to biting the arm of Javier Mascherano on Sunday.
West Ham United's Mark Noble admitted with rare post-match candour that they were fortunate to escape with a 3-0 defeat by Southampton at the London Stadium on Sunday - their fourth successive reverse in the Premier League.
News of all that's transpired on and off the football field
Chelsea manager Antonio Conte indicated that striker Diego Costa will stay at the club, despite a series of reports in the Spanish media linking him with a return to Atletico Madrid.
Sheffield United finished the season in 18th place with a goal difference of -23, a single goal worse than Wigan, to join already relegated Charlton Athletic and Watford in the second division.
Charlton were relegated from the Premier League after losing 2-0 at home to Tottenham Hotspur.
Arsenal scored twice in the last six minutes to secure a 3-1 home victory over Fulham that left their London rivals deep in relegation danger.
West Bromwich Albion forward Nicolas Anelka has denied an English FA charge regarding an alleged anti-Semitic gesture he made during last month's 3-3 Premier League draw at West Ham United, his club said on Thursday.
West Ham United's bid to re-sign Carlos Tevez stalled because of the striker's salary demands, the Premier League side's co-chairman David Sullivan has said.
Heavyweight trio Manchester City, Manchester United and Chelsea kept up their 100 per cent starts to the Premier League season this weekend.
Arsenal's best chance to equalise came from a Granit Xhaka free kick which looked destined for the top corner until the Gunner's former keeper Emiliano Martinez at full stretch pushed it around the post with a fingertip save.
Liverpool are champions and Norwich City, the side whom they beat on Aug. 9 to launch their title charge, are down and Manchester City are distant runners-up. After that everything is up for grabs.
ManchesterCity manager Pep Guardiola has expressed doubts over whether Manchester United can challenge for the Premier League title but believes they have a realistic chance of finishing in the top four.
Australia's goalkeeper Mark Schwarzer fractured a cheekbone playing for Middlesbrough in the FA Cup semi-final against West Ham United.
Images from Sunday's Premier League matches.
English Premier League strugglers Charlton Athletic parted company with manager Les Reed on Sunday and appointed former West Ham United manager Alan Pardew in his place.
The top three places in the Premier League table look secure for Liverpool, Manchester City and Leicester City, but the fourth spot, currently occupied by Chelsea, remains tantalisingly within reach for several clubs including Carlo Ancelotti's Everton and Ole Gunnar Solskjaer's United.
Manchester United beat West Ham United 1-0 to consolidate their second place in the EPL
After 18 matches in the EPL, United lead with 44 points, Chelsea are second on 42 and Liverpool third on 31.