The epicentre of the quake, measuring 6.1 on the Richter scale, was Afghanistan-Tajikistan border and it occurred at 4.01 pm.
There were no reports of loss of property or life.
15 people were injured in Kathmandu as people ran away from their houses in panic during the tremor, according to the home ministry spokesperson.
At least 30 people were killed in a landslide triggered by the continuous rainfall that has buried six villages in Nepal's mountainous northeast.
Four fresh tremors on Sunday jolted Nepal, triggering panic among the people already battered by the devastating earthquake and over 150 aftershocks as the death toll crossed 8,000.
The death toll in Nepal from this week's earthquake has risen to 110, authorities said on Thursday even as a fresh tremor, measuring 4.5 on the Richter scale, was felt in Nepal on Thursday.
Two fresh tremors were felt in Nepal on Friday, triggering panic among the people.
Rescuers in quake-hit Nepal on Friday located three charred bodies and the wreckage of a US Marine helicopter that went missing while delivering aid in the devastated Himalayan nation as death toll from the fresh quake reached 117 amid three fresh tremors.
Rescue teams from India and 33 other countries were on Saturday asked by Nepal to leave as it prepared to launch massive operations to rehabilitate millions of uprooted victims of the devastating temblor that has killed at least 7,365 people, including 41 Indians.
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