Villarreal's struggles in the Spanish league continued with a 2-1 loss at Athletic Bilbao, with striker Gerard Moreno not finishing the game because of an injury.
Athletic Bilbao ended tiny Mirandes's remarkable run with a ruthless 6-2 win in their King's Cup semi-final second leg on Tuesday to set up a final with either Barcelona or Valencia.
Athletic Bilbao, conquerors of Manchester United in the previous round, continued their Europa League run by scoring three times in the last 20 minutes to win their quarter-final first leg tie 4-2 at Schalke 04 on Thursday.
Jeremy Mathieu grabbed a late winner for Valencia to put them third in La Liga as they overcame 10-man Athletic Bilbao 2-1 away on Sunday.
Iker Muniain gave Athletic a deserved lead in the 32nd minute by bundling the ball home after Real failed to get back in time to defend a counterattack.
Barcelona's Sergi Roberto and Robert Lewandowski struck just before halftime to give the league leaders a 2-0 home win over lowly Cadiz on Sunday in their pursuit of a 27th Spanish title.
Barcelona winger Raphinha secured a 1-0 win in LaLiga for the second straight week this time at Athletic Bilbao as his side tightened their grip on top spot.
Football action from across Europe in matches played on Saturday
Hazard extra-time goal sends 10-man Real Madrid through to Copa del Rey final.
The hard-fought win took Zinedine Zidane's side on to 77 points after 34 games, seven clear of second-placed Barca who visit in-form Villarreal later on Sunday.
Images from action in the Spanish Super Cup and English Premier League
Joao Miranda and new signing Mario Mandzukic led Atletico Madrid to a 2-1 home win in La Liga on Saturday as visitors Eibar were unable to cope with the aerial threat of the champions.
Images from the football matches played across Europe on Wednesday.
Champions Barcelona came through a gruelling La Liga test at a rainswept San Mames on Sunday, beating Athletic Bilbao 1-0 thanks to Ivan Rakitic's first-half header.
Lionel Messi was at the top of his game as Barcelona earned a 3-2 win at Athletic Bilbao on Wednesday to move up to third in La Liga.
Portugal international Goncalo Guedes fired Valencia into the lead in the 35th minute with a thumping shot from inside the area which was too powerful for Madrid goalkeeper Keylor Navas.
News of all that's transpired on and off the football field
Images from the soccer matches played across Europe on Saturday.
A round of Saturday's matches in Series A, La Liga and Bundesliga.
Liverpool manager Juergen Klopp enjoyed a satisfying return to Borussia Dortmund as his new side frustrated his former charges and claimed a valuable away goal to draw 1-1 in their Europa League quarter-final, first leg on Thursday.
La Liga leaders Real Madrid suffered a surprise 1-0 defeat at mid-table Athletic Bilbao on Saturday after a bullet header from Aritz Aduriz in the first half secured the points.
News of all that's transpired on and off the football field