Here is a round-up of results from the European League matches played on Wednesday
Edin Dzeko scored twice to set up a 3-1 win for AS Roma away to Napoli in the battle for second place in Serie A on Saturday and Paulo Dybala also notched up a brace for leaders Juventus in their 2-1 win over Udinese.
Defender Miguel Britos was sent off for head-butting an opponent as Napoli lost 3-1 at champions Juventus on Saturday, all but ending their hopes of Champions League football next season.
Chelsea's Ruben Loftus-Cheek had a Europa League night to remember by scoring the first hat-trick of his career as the midfielder inspired them to a 3-1 home win over Belarus champions BATE Borisov on Thursday.
Napoli thrashed Frosinone 5-1 away to go top of Serie A on Sunday after previous leaders Inter Milan were sunk by a Domenico Berardi penalty in the fifth minute of injury time in a 1-0 home defeat against modest Sassuolo.
Real Madrid defender Nacho was the unlikely hero as they snatched a 1-0 win at Real Valladolid on Sunday to capitalise on Barcelona's defeat at Valencia this weekend and move three points clear of their rivals at the top of La Liga. Serie A leaders Juventus suffered a shock 2-1 defeat at Napoli on Sunday, with coach Maurizio Sarri returning to his former club for the first time, though Cristiano Ronaldo still managed to score for an eighth league game in a row for the visitors.
Fiorentina hit four goals before halftime, including a cheeky backheel by Gonzalo Rodriguez and a Panenka-style penalty from Khouma Babacar, to beat Frosinone 4-1 and join Inter Milan at the top of Serie A on Sunday.
Later on Monday, Lukaku's brace helped Inter to a win over Napoli, taking them atop the standings on goal difference from Juventus.
Knee injuries have sidelined him for large parts of this season, however, and the Belgium international has started only four Premier League games.
Brazil playmaker Kaka scored his first goal, a delightful curling shot, since his return to AC Milan at the start of the season but his struggling team were held 1-1 at home by Lazio in Serie A on Wednesday.
Juventus's hopes of reaching the Champions League last eight suffered a blow when the two-times European Cup winners slumped to a 1-0 defeat in their last-16 first leg at Olympique Lyonnais on Wednesday. Manchester City finally produced a Champions League performance worthy of their status as one of European football's elite clubs by beating Real Madrid 2-1 away in Wednesday's last-16 first leg after pulling off a stunning late fightback.
Barcelona's Lionel Messi and Luis Suarez secured victory over nine-man Atletico Madrid in La Liga's top of the table clash, while Juventus won a 12th straight Serie A game to stay hot on the heels of leaders Napoli.
Lazio survived a storming Napoli fight back, including a missed penalty, as they won 4-2 on Sunday to finish third in Serie A and qualify for the Champions League playoff round after both teams finished with 10 men.
Gonzalo Higuain pulled one back three minutes later with a typically opportunist goal, the Argentine's 13th in the league this season, to set up a tense final half hour.
Photographic summary of the football matches played across Spain, Italy and France
Ronaleo netted his 14th league goal for Juve this season while PSG's winning streak was snapped by Monaco in a 3-3 draw. Here are images from the matches played on Sunday
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
Two goals in three minutes from Napoli's Goran Pandev were not enough to secure victory as his side threw away a two-goal lead to draw 3-3 at home to Udinese in an end-to-end Serie A thriller on Saturday.
Genoa handed Serie A leaders and titleholders Juventus a dramatic first league defeat of the season when Luca Antonini scored in the fourth minute of stoppage time to give them a 1-0 win on Wednesday.
Lionel Messi announced on Friday that he wants to return to play for the national team, reversing his decision to retire earlier this year. Messi said in June that he would not play for Argentina again after the team lost to Chile in the final of the Copa America.
News of all that's transpired on and off the football field
News of all that's transpired on and off the football field
The Frenchman has failed to bring in any of his top targets in the close season and said he is still in the market for some new talent before Monday's transfer deadline.
Alessandro Florenzi ran more than half the length of the field to score and cap a 2-0 win for AS Roma over Genoa which took them back into second place in Serie A on Sunday.
Lionel Messi scored his 55th international goal to become his country's all-time leading scorer as Argentina thrashed hosts the United States 4-0 to ease into the final of the Centenary Copa America on Tuesday.
Images from the EPL matches played on Sunday
News of all that's transpired on and off the football field
Liverpool's livewire Sadio Mane scored one goal and played a crucial part in the other as they reclaimed the Premier League's top spot with a scrappy 2-1 win at second bottom Fulham on Sunday.
News of all that's transpired on and off the football field
Barcelona's lead at the top of La Liga was cut after a second consecutive defeat and LeicesterCity's improbable march towards the Premier League title showed no sign of slowing as they won a fifth straight match. Juventus stayed six points clear of Napoli after Italy's top two both won and Bayern Munich extended their Bundesliga lead to seven points. Here is a summary of results from football matches played across Europe over the weekend.
Napoli's decision to loan Emanuele Calaio to Genoa came back to haunt them on Monday when the 32-year-old scored with a late free kick in a 1-1 Serie A draw costing his owners two points in the race for a Champions League spot.
News of all that's transpired on and off the football field
To finish with dignity is how Robin van Persie wants to end his playing days on Sunday when he hangs up his boots after an 18-year career.
Inter Milan went on a rare scoring spree to thrash Serie A newcomers Frosinone 4-0 and go clear at the top on Sunday, the first time Roberto Mancini's team have won a league match by more than one goal this season.
Francesco Totti made an instant impact on his return from a buttock injury when he scored one goal and helped set up another in AS Roma's 3-2 Serie A win over Udinese on Monday.
News of all that's transpired on and off the football field
Argentina and Chile advanced to the semi-finals of the Copa America on Saturday with Chile beating Mexico 7-0 and Lionel Messi getting a goal in Argentina's 4-1 win over Venezuela to equal his country's all-time scoring record.
A round-up of Saturday's action in Serie A, La Liga and Bundesliga.
The former Paris St Germain manager will be presented on Wednesday and will replace Jose Mourinho who left at the end of last season to join Chelsea.
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