Medvedev opened as the +225 favorite at BetMGM but has seen his odds lengthen slightly despite the absence of two of his top threats. He has had a rollercoaster 2022 since falling to Nadal in the Australian Open final.
Rafael Nadal returns to the US Open for the first time in three years short of match practice and with big question marks about his fitness but few people will dismiss the Spaniard's chances of claiming a record-extending 23rd Grand Slam title.
'Serena must be prepared to live with it and say goodbye even in the face of defeat'
Images from Day 2 at the US Open played at Flushing Meadows in New York on Tuesday
Swiss third seed Stanislas Wawrinka outlasted tiring former champion Juan Martin del Potro in four sets to advance to the semi-finals of the US Open on Wednesday.
Top seed Agnieszka Radwanska declared it mission accomplished after clinching a 6-1, 7-6(1) victory over Elina Svitolina in the final of the Connecticut Open in New Haven on Saturday.
Japan's Nishikori was the first man representing an Asian country to break through to a Grand Slam final at the 2014 tournament before Marin Cilic stopped him in the title match.
'We love our sport but it puts everything into perspective'
Indian Wells organisers said on Tuesday that world number two Novak Djokovic had been placed in the tournament's draw but it was unclear if the Serbian would be permitted to enter the United States.
Frenchman Jo-Wilfried Tsonga has withdrawn from the US Open due to a long-term knee problem, the United States Tennis Association said on Monday.
Rafael Nadal turned dream wrecker at Flushing Meadows when he downed American favourite Mardy Fish 3-6, 6-1, 6-4, 6-2 in a rowdy late late show that closed Wednesday's programme at the US Open.
Sharapova, making her return to top-flight tennis after serving a doping ban, defeated Romanian Halep 6-4, 4-6, 6-3 to move into the 2nd round of the final major of the year.
The US Open kicks off on August 31 and will be held in its usual home in Flushing Meadows, Queens, but will be played without fans in attendance to limit the spread of the virus.
Flavia Pennetta reached her first grand slam semi-final after beating Roberta Vinci 6-4, 6-1 in their all-Italian quarter-final at the US Open on Wednesday.
IMAGES from Day 7 of the matches played at the US Open at Flushing Meadows on Sunday.
A look at the 10 landmark matches from the 20-times Grand Slam champion's career.
Wimbledon finalists Novak Djokovic and Roger Federer are on a semi-final collision course at the US Open after they were placed in the same half of the draw.
Off-court distractions and a neck injury could not prevent Novak Djokovic from extending his winning run this year to 23 matches and the Serbian could not be in more intimidating form ahead of the US Open.
The former world number one was especially proud of the way she has managed to mould her mindset to deal with tough losses.
Novak Djokovic, who won Wimbledon to take his major singles titles to 21, has opted not to be vaccinated against COVID-19. He said on Thursday he could not fly to New York for the year's final Grand Slam.
Novak Djokovic won a record-extending sixth Paris Masters title by avenging his U.S Open final defeat against Russian Daniil Medvedev with a 4-6, 6-3, 6-3 victory in Sunday's showpiece match.
'I definitely think it's the time to just switch off from any future thoughts or any plans, any schedule. I've got absolutely no clue. Right now, no care in the world, I'm just loving life.'
World number one Novak Djokovic had to work hard for a three-set victory over Hungarian Marton Fucsovics at the Paris Masters on Tuesday in his first match since losing the U.S. Open final in September.
Kei Nishikori's hopes of playing at the US Open have faded further after the Japanese former world number four revealed he had tested positive for COVID-19 for a second time.
A summary of Friday's action at the US Open.
Indian tennis ace Sania Mirza and her Chinese partner Jie Zheng cruised into the quarter-finals of the women's doubles at Flushing Meadows.
IMAGES from matches on Day 4 of the US Open at Flushing Meadows in New York on Thursday.
Iga Swiatek's maiden triumph at the US Open extended her lead to almost twice as many points as the second-ranked Ons Jabeur
Fifth seed Simona Halep narrowly avoided a third-round upset with a 6-1, 2-6, 6-4 win over Hungary's Timea Babos on Saturday to keep her US Open title hopes alive.
Novak Djokovic beat Casper Ruud in the French Open final to win a men's record-extending 23rd Grand Slam title.
Norway's Casper Ruud harnessed his mighty forehand to reach his second Grand Slam final this year by beating Russia's Karen Khachanov 7-6(5), 6-2, 5-7, 6-2 at the US Open, keeping alive his hopes of reaching the top of the world rankings.
A summary of Thursday's action at the US Open.
Images from Day 6 of the 2021 US Open in New York on Saturday.
American Rajeev Ram and Briton Joe Salisbury overcame a slow start to beat Bruno Soares and Jamie Murray 3-6, 6-2, 6-2 in the US Open men's doubles final on Friday.
Serena Williams appeared to suggest last month that she would end her playing career at the U.S. Ope
Here are eight women to watch during the US Open which starts on Monday.
Geopolitical tensions simmered at the US Open on Thursday as Ukrainian Marta Kostyuk refused the customary handshake at the net when Belarusian Victoria Azarenka defeated her 6-2, 6-3 in the second round.
Images from Day 5 of the 2021 US Open in New York on Friday.
Big serving Berrettini is having a breakout year, with two titles under his belt, one on grass and one on clay, and is now on the brink of becoming the first Italian male grand slam finalist in more than 40 years.
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