Chelsea demolished the team that succeeded them as Premier League winners when champions Leicester City succumbed tamely 3-0 at Stamford Bridge on Saturday.
Frank Lampard and Edin Dzeko scored twice as holders Manchester City sailed into the English League Cup fourth round with a crushing 7-0 win over Sheffield Wednesday and Chelsea beat Bolton Wanderers 2-1 on Wednesday.
After seven consecutive league defeats, and one point from the last 30 on offer, had plunged Villa into crisis and cost Tim Sherwood his job, the former European champions produced a gritty display to frustrate City.
There was the usual frenzy of last-minute deals as the English Premier League brought the curtain down on another bumper European transfer window in which Manchester City again flexed their financial muscle as the continent's top spenders.
Liverpool's hopes of winning their first title in 24 years suffered a huge setback when they lost 2-0 at home to Chelsea and Manchester City took advantage with a 2-0 victory at Crystal Palace.
Chelsea scrambled a stoppage-time winner to snatch a 1-0 victory over Everton on Saturday, showing their Premier League title mettle by claiming three points when they looked on course to suffer another damaging blow.
Jose Mourinho suffered a nightmare homecoming as Porto, the club he led to the Champions League title in 2004, inflicted a 2-1 defeat on his woefully out-of-sorts Chelsea side in Group G on Tuesday.
Willian's late strike snatched a 1-0 home win for Chelsea over a stubborn Everton side to maintain lead.
Images from the English Premier League matches played at Old Trafford on Saturday
Following is a match by match look at the English Premier League's season-opening weekend fixtures:
Here is a summary of stories from the English Premier League
'I think it's unacceptable what he does to Koscielny. He pushes him down, he hits him in the face. I do not understand Mike Dean's decision at all. Why does Diego Costa stay on the pitch and Gabriel is sent off?' 'If you want to speak about Diego Costa with me, it's just to say he played like he has to play and that's why you have full stadiums, you sell to television around the world for millions and millions because the game has to be played like that'
Samuel Eto'o's hat-trick lifted Chelsea to a 3-1 win over Manchester United on Sunday which all but ended the champions' slim hopes of defending their Premier League title.
A fixture billed as a pre-Christmas cracker was more 'In the Bleak Midwinter' than 'Jingle Bell Rock' as Arsenal's hopes of regaining top spot in the Premier League fizzled out in a turgid 0-0 draw with Chelsea.
A round-up of Euro 2016 warm-up matches played on Sunday
The Netherlands failed to reach the European Championship for the first time since 1984 as they lost 3-2 at home to the 10-man Czech Republic in their final qualifier on Tuesday to miss out on Euro 2016.
Chelsea's title ambitions suffered a major blow with a shock 2-1 home defeat by bottom side Sunderland on Saturday, handing the initiative to English Premier League leaders Liverpool who visit lowly Norwich City on Sunday.
Jose Mourinho maintained his hold over Arsene Wenger with leaders Chelsea enjoying a routine 2-0 win over Arsenal on Sunday after the two old adversaries became involved in an ugly touchline spat.
Malta make Italy sweat, while Bale takes Wales closer to competition
A round-up of all the international friendlies played on Tuesday
Belgium make Wales wait after Hazard's strike, while Czechs beat Latvia to qualify