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The American is hoping that belief will help her rekindle the Wimbledon magic that launched her into the public eye five years ago.
After a long rain delay Germany's Sabine Lisicki made quick work of Venus Williams, strolling into the second round of the Rogers Cup on Monday after routing the American 6-0 6-3.
With Serena bidding to become just the fourth woman to win all four grand slams in the same year, the US Open hype machine that already had been in top gear is now set to crank into overdrive.
Images from Day 6 of the Australian Open in Melbourne on Saturday.
The top seed was forced to dig deep into her vast reservoirs of experience to stave off Pliskova's challenge and emerge a 7-5, 7-6(6) winner against the gutsy Czech.
IMAGES from the matches played at Miami Miasters in Key Biscayne, Florida, on Wednesday
The sun beat down from a cloudless Parisian sky on Sunday as the French Open began with a sultry Venus Williams raising the on-court temperature and French favourite Jo-Wilfried Tsonga almost getting caught cold.
After four days of play, the French Open was left without a Williams sister in the draw on Wednesday when former runner-up Venus joined 2002 champion Serena in making an early exit.
Images from Day 1 of the 2020 French Open, in Paris, on Sunday.
Sania Mirza will take on Venus Williams in the opening singles match at the Watson Water Champions Challenge.
A big serve to the backhand side clattered off the racket of third-seeded twice champion Venus Williams and the Belgian, returning to the grand slam stage after more than two years away, had a 6-0, 0-6, 6-4 win and a spot in the quarter-finals.
On June 6, 2012, Venus will pass across the face of the sun, producing a silhouette that no one alive today will likely see again.
Champion Venus Williams powered through to her seventh Wimbledon final with a 6-1, 7-6 victory over Russian Elena Dementieva.
Champion Venus Williams and second seed Rafael Nadal survived a few anxious moments to reach the third round of Wimbledon. Williams, seeking a fifth singles title at the All England Club, had to draw on all her big-match experience to repel world number 92 Anne Keothavong 7-5, 6-2 while Nadal also endured some first-set jitters before toppling rising Latvian Ernests Gulbis 5-7, 6-2, 7-6, 6-3.
American Williams, seeded 10th and competing in her 20th French Open, powered 22 winners and converted six of 13 break points as she picked apart the 60th-ranked Belgian in just over an hour.
American Venus Williams marked her return from an abdominal injury with an impressive 7-5, 5-7, 6-3 victory over Germany's Andrea Petkovic at the Eastbourne championships on Monday.
Serena Williams summoned all her fighting qualities to beat Victoria Azarenka 4-6, 7-6, 6-2 at the Australian Open on Wednesday after sister Venus's exit. Li Na earlier stunned Venus to become just the second Chinese to reach the semi-finals of a Grand Slam.
Venus Williams overwhelmed third-seeded Russian Dinara Safina 6-4, 6-2 to reach the semi-finals of the Stuttgart Grand Prix.
The win makes her the oldest woman to reach the third round at the French Open since Billie-Jean King in 1982.
South Korean Chung Hyeon managed to hang around against Roger Federer a little longer this time around, but only just, as the Swiss maestro advanced to the semi-finals of the BNP Paribas Open 7-5, 6-1 on Thursday.
When in Landour, discovers Supriya Newar, one of the most important things to do and that too in large measures, is to do nothing at all.
Venus and Serena Williams won the US Open women's doubles crown on Monday with a dominating 6-2, 6-2 victory over top seeds Cara Black and Liezel Huber.
Serena Williams battered Anastasia Pavlyuchenkova 6-4, 6-4 in the quarter-finals at Wimbledon on Tuesday, seizing on moments of weakness from the Russian to ram home her advantage.
With speculation rife that Rio Olympics silver medallist Venus Williams was allegedly allowed to use prohibited substance under Therapeutic Use Exemptions (TUEs) clause, Indian tennis ace Sania Mirza on Friday rubbished reports suggesting that she has demanded the All India Tennis Association (AITA) to raise the matter with the appropriate authorities.
Flavia Pennetta stunned Venus Williams with an impressive 6-4, 7-6 win to reach the Bangkok Open final.
Serena Williams applied some coaching tips from older sister Venus in her 6-3 6-2 thumping of sixth-seeded Dinara Safina on Friday that put the American into the finals of the US Open.
Top seed Venus Williams was stunned in the first round of the Memphis International by Czech qualifier Petra Kvitova.
A display of raw desire over a decade ago from sister Serena inspired Venus Williams to ascend the summit of the women's game but there will be no room for sentiment when the siblings meet for the fourth time in a Wimbledon final on Saturday.
Grand Slam finalists Garbine Muguruza and Roberta Vinci stormed into the last four of the Wuhan Open in China on Thursday while Venus Williams ended the giant-killing run of Briton Johanna Konta.
Jana Novotna, who lifted the Wimbledon title 26 years ago in 1988, tragically died in 2017 following a battle with ovarian cancer aged 49.
The American was one game away from tumbling out but, as rain began to fall again on the grasscourt tournament, she outsmarted Akiko Morigami 6-2 3-6 7-5.
World No 1 Serena Williams and her sister Venus tried their hand at cricket with the Melbourne Renegades players on a hotel roof top on Thursday.
Venus Williams suffered a shock 4-6, 7-6, 6-4 defeat by France's Virginie Razzano in the Japan Open final.
Nadia Petrova lost 6-3, 6-3 to Italy's Mara Santangelo in the second round of the Warsaw Cup.
Venus Williams moved within two wins of a possible sisterly showdown with Serena in the semi-finals of the US Open by beating German 26th seed Laura Siegemund to reach the fourth round on Saturday.
Wimbledon champion Venus Williams blasted past Alona Bondarenko of Ukraine 6-1 6-2 on Friday to charge into the fourth round of the U.S. Open.
Madison Keys continued to ride her wave of success, fuelled in part by celebratory chocolate biscuits, as she advanced to her first Grand Slam semi-final with a gutsy 6-3, 4-6, 6-4 victory over Venus Williams on Wednesday.