United, 1-0 up from the first leg quarter-final at Chelsea, beat their Premier League opponents 2-1 at Old Trafford, while Barcelona, 5-1 up from the first leg, won 1-0 at Shakhtar Donetsk.
Real Madrid extended their lead in Spain to eight points after crushing Valladolid 7-0.
Two more goals from irrepressible midfielder Cristiano Ronaldo helped Manchester United to a 3-1 home win over Tottenham Hotspur in their FA Cup fourth-round tie on Sunday.
Wayne Rooney produced a spectacular overhead kick to earn Manchester United a 2-1 victory over Manchester City and a seven-point lead in the Premier League on Saturday.
Arsenal resume battle with Manchester United at the top of the Premier League on Saturday.
The top two teams in the EPL will battle for supremacy at the Emirates Stadium on Saturday.
Manchester United beat AS Roma 1-0 in the second leg of their Group F Champions League meet.
Premier League champions Manchester United suffered a shock League Cup exit for the second season running when they lost 2-0 at home to second division Coventry City on Wednesday.
Manchester United and AS Roma will meet in the Champions League group stages.
Argentine striker Carlos Tevez will make his Manchester United debut on Wednesday.
Chelsea are favourite among those Champion Legaue contenders with little European pedigree.
Newcastle United striker Andy Carroll has been charged with assaulting a teenage girl, police said on Monday.
The EPL champions, old and new, produced a strictly mid-table performance in a goalless showdown.
Arsenal's Spanish striker Jose Antonio Reyes has been banned for three games after an FA disciplinary commission found him guilty of violent conduct.
The 38-year-old is struggling to shake off a knee injury he picked up in Milan's 3-2 defeat at Old Trafford last week.
Cristiano Ronaldo inspired Manchester United to a 4-1 rout of Bolton Wanderers while Chelsea beat Sheffield United 3-0.
AZ Alkmaar sunk Newcastle United 2-0 on Thursday to reach the UEFA Cup quarter-finals on the away goals rule.
North East United FC had a pretty forgettable inaugural season, but they look to make amends in the second edition of the Indian Super League.
The Premier League game between Manchester United and Bournemouth on Sunday was abandoned after two stands at Old Trafford were evacuated before kickoff.
Manchester United beat Aston Villa 3-1 to maintain their six-point Premier League lead.
Chelsea cut Manchester United's Premier League lead to five points after Didier Drogba scored the winner in a 1-0 victory over Newcastle United on Wednesday.
The result left Manchester United top of the EPL standings on 35 points, three ahead of Chelsea.
Holders Bayern Munich recovered from the shock of a stunning Patrice Evra goal to score three times in quick succession to beat Manchester United 3-1 and reach the Champions League semi-finals on Wednesday.
Crystal Palace set up a repeat of the 1990 FA Cup final against Manchester United after Yannick Bolasie and Connor Wickham securd a 2-1 victory over Watford at Wembley on Sunday.
In an all-Spanish clash, former winners Barcelona were drawn against Atletico Madrid in the Champions League draw, while Real Madrid will take on Borussia Dortmund. Paris Saint-Germain were handed a tough draw against Chelsea.
It was an epic night of high drama, and Robin van Persie was at his lethal best. The Dutch striker came up with a stunning hat-trick to lift the pressure on David Moyes and gloom surrounding Manchester United.
Bayern Munich weathered a fierce Manchester United onslaught on Wednesday to reach the semi-finals of the Champions League on away goals after a 3-2 defeat at Old Trafford.
Manchester United agreed a fee of up to $34.59 million for Tottenham midfielder Michael Carrick.
Manchester United's early exit from the Champions League last season cost the English club almost 17 million euros in payments from UEFA compared with the previous year, figures released on Friday showed.
Manchester United's top-four aspirations suffered a setback as Louis van Gaal's side were blown away 3-0 by Everton.
"Cristiano recently signed a new contract until 2010 and the club fully expects him to honour that contract," Manchester United said.
Manchester United were frustrated in their bid to secure second place in the EPL as they were held 0-0 by Middlesbrough
Manchester United received some welcome relief from the English soccer champions' on-pitch woes with the announcement on Friday of a sponsorship deal with Italian spirits brand Aperol.
David de Gea's late own goal earned Sunderland a 2-1 win over Manchester United on Saturday and a vital three points in their bid for Premier League survival.
Arsenal thrashed Middlesbrough 7-0, while Manchester United lost 3-1 at Manchester City in the Premier League.
Didier Drogba scored twice on his return from a three-match European suspension as Chelsea drew 2-2 at Atletico Madrid to seal their place in the knockout round of the Champions League on Tuesday. They were joined in the last 16 by Manchester United, Porto and Girondins Bordeaux, although four-time European champions Bayern Munich are on the brink of elimination after losing at home to the French champions.
Liverpool lifted the gloom hanging over their season with a 2-0 victory over Premier League champions and fierce rivals Manchester United on Sunday.
Second-half strikes from Wayne Rooney, Juan Mata and Jesse Lingard earned Manchester United a morale boosting 3-1 win over Premier League rivals Liverpool in the final of the pre-season International Champions Cup in Miami on Monday.
Manchester United must end a surprising three-match scoring drought to avoid Champions League elimination in Lisbon.
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