Leaders Chelsea stretched their Premier League winning run to a club record-equalling 11 as Diego Costa's header shortly before halftime secured a 1-0 victory at London rivals Crystal Palace on Saturday.
United down Newcastle after Saints stun Chelsea on a dramatic night in the English Premier League.
Jamie Vardy scored his first goal in the Champions League to give Leicester City some hope of staying in Europe's elite competition despite a 2-1 loss to an utterly dominant Sevilla in Wednesday's last-16 first leg.
Images from the EPL matches played on Saturday
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Aston Villa were crushed 6-1 by Southampton but joined Leicester City in celebrating Premier League survival on Saturday while Steven Gerrard's farewell party was spoiled as Liverpool lost 3-1 to Crystal Palace.
The owners of English soccer champions Leicester City say they will resist attempts by more glamorous rivals to lure away their title-winning players, after an unlikely triumph that has captured the imagination of fans worldwide. Duty-free magnate Vichai Srivaddhanaprabha became the first Thai owner of an English Premier League title-winning team on Monday night, when the only club capable of catching them, Tottenham Hotspur, were held to a 2-2 draw by Chelsea. Leicester's journey from 5,000-1 outsiders to English champions has captivated soccer lovers everywhere, but also prompted predictions that the team could be broken up in the off-season as bigger clubs look to poach their best players. "We are not the team that will sell players for money," said Aiyawatt Srivaddhanaprabha, the club's vice chairman and Vichai's son, in comments reported by Thai website Manager. "So, I can confirm that we will keep all major players with the team, such as Jamie Vardy, Riyad Mahrez, N'Golo Kante or Kasper Schmeichel."
The statistics of a stunning campaign tell an astonishing tale of how Leicester have turned the clock back by shunning possession and glorying in the long ball to a pacey striker, while spurning rotation in favour of a settled, almost self-selecting side
First-half goals by Danny Welbeck and Alex Iwobi earned Arsenal a first win in four league games to revive their Premier League title hopes in the early kickoff at Goodison Park on Saturday.
Gareth Southgate's plea for England to play with adventure and style was answered only fitfully as his reign as caretaker manager began with a 2-0 win over Malta in a World Cup Group F qualifier on Saturday.
Steven Gerrard's future at Liverpool may be in doubt but the captain turned back the clock to score in a 3-1 victory at bottom side Leicester City in the Premier League on Tuesday.
Harry Kane's magical season continued on Saturday as he celebrated his first senior England call-up with his first Premier League hat-trick.
A stunning double from captain Zlatan Ibrahimovic gave Sweden a 2-2 draw away to Denmark as they qualified for Euro 2016 on Tuesday by winning 4-3 on aggregate against their Scandinavian rivals.
Manchester City made sure of third place in the Premier League when they romped to a 5-0 win at Watford on Sunday to ensure a Champions League berth for next season.
'Keep Calm And Carry On' could be Claudio Ranieri's motto for the second half of the season after Leicester City earned a 1-0 win at Tottenham Hotspur on Wednesday to put the heat back on Premier League leaders Arsenal.
The mesmerising moments that made the 2018 FIFA World Cup a blockbuster worldwide.
A headed goal in second-half injury time by Cristiano Ronaldo gave Portugal a much-needed 1-0 win over Denmark in their Group I Euro 2016 qualifier on Tuesday.
Liverpool substitute Adam Lallana struck deep into stoppage time to snatch a 5-4 win over shell-shocked Norwich City in an extraordinary Premier League game at Carrow Road on Saturday.
Poland struck twice on the break to stun wasteful World Cup winners Germany 2-0 on Saturday, earning their first ever victory over their illustrious neighbours and taking control of Euro 2016 qualifying Group D.
Schuerrle hits treble for the world champs; Lewandowski helps Poland thrash Georgia
Roberto Firmino's goal gave Brazil a 1-0 victory over Chile in a feisty friendly at the Emirates Stadium in London on Sunday, their eighth successive win since last year's disappointing World Cup campaign.