Hamilton held off a mid-race challenge from Red Bull's Max Verstappen to register a record-equalling fourth triumph at the floodlit Marina Bay Street Circuit track, while Vettel finished third to slip further behind in the title race.
A glaring error by Ferrari denied Charles Leclerc the chance to shine at home, with the 21-year-old failing to make it through the first phase and qualifying only 16th after going fastest in final practice.
Lewis Hamilton said he was ready for a new beginning in Brazil at the end of the Formula One season and spoke on Thursday of his hope of re-kindling his romance with singer Nicole Scherzinger.
Red Bull's Formula One World champion Max Verstappen took pole position for the Australian Grand Prix on Saturday with Carlos Sainz qualifying alongside on the front row for Ferrari two weeks after undergoing surgery for appendicitis.
Lewis Hamilton believes his Mercedes Formula One team can live up to their advance billing as favourites when the season starts in Australia next week.
The Mercedes driver discusses the strength of his faith -- along with a wide selection of topics ranging from his hatred of school and his dyslexia to the frozen sperm and $700-a-day modelling career of his pet bulldog Roscoe.
After pipping Ferrari's Sebastian Vettel with a lap of one minute 23.599 seconds in the first practice, the Briton shaved almost a second in FP2, his quickest lap clocked at 1:22.60.
Lewis Hamilton pulverised the track record to claim pole position on Saturday ahead of a US Grand Prix that could secure the Mercedes driver's fourth Formula One world championship.
Lewis Hamilton put Monaco misery behind him on Sunday with a controlled Canadian Grand Prix victory.
Triple Formula One world champion Lewis Hamilton beat team mate Nico Rosberg to pole position at the Spanish Grand Prix on Saturday in a front row sweep for dominant Mercedes.
Red Bull's Dutch 20-year-old Max Verstappen took the chequered flag in second place with Kimi Raikkonen completing the podium for Ferrari and Australian Daniel Ricciardo finishing fourth for Red Bull.
Lewis Hamilton's world championship defence got off to a flying start on Sunday with a crushing victory for Mercedes in the season-opening Australian Grand Prix as Formula One rivals succumbed to a farcical rash of reliability problems.
Reigning F1 champ warns Bottas about Hamilton rivalry
Sebastian Vettel's hopes of vaulting back into the overall Formula One world championship lead were wrecked by a first corner collision on the opening lap of the Singapore Grand Prix.
Formula One world champion Lewis Hamilton took pole position for the Austrian Grand Prix on Saturday with Mercedes team mate and overall leader Nico Rosberg set to start seventh after a grid penalty. Force India's Nico Hulkenberg joined the Briton on the front row, only his second career top-two start, although the German was under investigation by stewards for a possible flag infringement.
Ferrari title rival Sebastian Vettel qualified only ninth.
Lewis Hamilton accused Mercedes team mate and Formula One championship leader Nico Rosberg of deliberately colliding with him at the Belgian Grand Prix on Sunday.
Formula One world champion Lewis Hamilton won the Canadian Grand Prix on Sunday in a Mercedes one-two with title rival Nico Rosberg.
Red Bull's Max Verstappen started the season with a commanding Bahrain Grand Prix win from pole position.
Formula One world champion Lewis Hamilton took pole position at the Spanish Grand Prix on Saturday in a Mercedes one-two that ended Sebastian Vettel's bid for a fourth in a row.
Ferrari, whose race on Sunday lasted about 20 seconds until Sebastian Vettel and Charles Leclerc collided, said the team strongly supported diversity and equal opportunities.
Mercedes driver Lewis Hamilton has insisted that his team must consult him on who would replace recently-retired world champion Nico Rosberg next season before also warning them against signing big names like Fernando Alonso.
Hamilton has won 71 races, 20 fewer than Schumacher, and four titles for Mercedes in the past five years. The first was with McLaren in 2008.
Electrical gremlins held up Lewis Hamilton in Italian Grand Prix practice on Friday after the Mercedes driver had lapped more than half a second quicker than anyone else in the morning session.
Formula One world champion Lewis Hamilton won the Hungarian Grand Prix from pole position for Mercedes on Sunday to go into the August break with a 24-point lead over Ferrari rival Sebastian Vettel.
"The comparison? I see still Ayrton winning the game because in the end Ayrton was such a charming guy and a personality. And obviously if someone loses his life and stays with us in the way of a legend, it's always something special. But I try to see it from a performance point and from a performance point, Lewis is going from one pole position to the next one and Lewis is going from one race win to the next one. Just like Ayrton did."
McLaren's Lewis Hamilton went from China crisis to champagne celebration on Sunday with a stirring victory that denied Red Bull's Formula One world champion Sebastian Vettel a fifth win in a row.
Formula One world champion Lewis Hamilton took pole position for the French Grand Prix on Saturday with Mercedes team mate Valtteri Bottas alongside him on the front row.
Lewis Hamilton had his driving licence suspended for a month after being caught speeding on a French motorway.
Finland's Valtteri Bottas took his first Formula One pole position at the Bahrain Grand Prix on Saturday with a sizzling lap that ended Mercedes team mate Lewis Hamilton's bid for a seventh in a row.
British media reports have suggested the new deal could be worth up to 40 million pounds ($52 million) a year and is likely to make the four-time F1 champion the sport's top earner.
The pole was a record-extending 82nd of Hamilton's career and his 10th of a season that has already seen the Briton clinch his fifth world championship.
Six time world champion Lewis Hamilton, winner of the British Grand Prix from pole position at the same circuit last weekend and 30 points clear of Valtteri Bottas after four races without spectators, was 0.138 seconds slower.
'The best part is if you get on the podium with them two, in the room before we go out on the podium just after the race, you take the helmet off and it's awkward for me because it's just so silent'
The Mercedes driver's 55th career win was hard-fought and tense, however, with Ferrari's Vettel seizing the lead at the start and in the hunt all the way to the finish as the tyre strategies played out.
Lewis Hamilton stepped out on to the Italian Grand Prix podium, high above the red tide of Ferrari.
Ferrari's Sebastian Vettel, the Briton's closest rival, finished only sixth after an early collision with Red Bull's Max Verstappen left the German fighting back from 19th place.
Lewis Hamilton won his home British Grand Prix for the fourth year in a row on Sunday while Ferrari's Sebastian Vettel suffered a penultimate lap puncture that slashed his championship lead to a single point.
Lewis Hamilton won the Monaco Grand Prix for Mercedes on Sunday, nursing his car's worn tyres to the finish in a nail-biting victory worthy of the team's late great Niki Lauda.
Former captain Kane Williamson, batsman Tom Blundell and quick Kyle Jamieson, who all have hamstring issues, were selected despite doubts over their fitness.