Knee injuries have sidelined him for large parts of this season, however, and the Belgium international has started only four Premier League games.
Manchester City's all-conquering season reached new peaks as Sergio Aguero became the club's all-time top scorer with a decisive goal in a thrilling 4-2 victory at Napoli that put them into the Champions League last 16 on Wednesday.
Manchester City claimed the win required to finally end Liverpool's relentless attempt to dethrone them as Premier League champions as they hit back from a goal down to crush Brighton and Hove Albion on the south coast on Sunday.
A round-up of Wednesday's night's UEFA Chmpions League matches.
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
News of all that's transpired on and off the football field.
A summary of Tuesday's group matches in the UEFA Champions League.
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