Factbox on the 20 Premier League clubs after the transfer window closed.
A round-up of Tuesday's action in the UEFA Champions League.
Manchester United veteran Ryan Giggs set a Champions League record on Wednesday but his side had little else to celebrate after a 1-1 draw at Shakhtar Donetsk in Group A.
Villarreal's Adrian Lopez produced a stinging sucker punch in stoppage time to leave Liverpool reeling and move the Spaniards closer to a maiden European final after their Europa League last four first leg clash finished 1-0 on Thursday.
With the away goals rule no longer in place this season, PSV missed a string of chances to force extra time with Eran Zahavi hitting the crossbar from three metres with the goal at his mercy in the 62nd minute.
David Moyes can take solace in avoiding another home defeat and a 51-year low but his Manchester United side will have to raise their game considerably if they are to go much further in the Champions League.
Captain John Terry will be back to plug Chelsea's porous rearguard on Wednesday when the holders bid to avenge last month's defeat by Shakhtar Donetsk and wrest back control of Champions League Group E.
Having played second fiddle to Bayern Munich domestically all season Borussia Dortmund again dazzled on the European stage as they crushed Shakhtar Donetsk 3-0 for a 5-2 aggregate win that took them to the Champions League quarter-finals on Tuesday.
Chelsea will start the defence of the Champions League trophy they won so dramatically last season with a Group E match against former winners Juventus at Stamford Bridge.
Manchester United breezed into the next round with a 6-1 aggregate win over Club Brugge
Six clubs enter this week's final round of Champions League group matches harbouring hopes of grabbing one of the three last-16 places still up for grabs although for holders Chelsea their fate is beyond their control.
Lionel Messi fired Barcelona into the last 16 of the Champions League with two goals in their 3-0 victory at Spartak Moscow on Tuesday but holders Chelsea are walking a tightrope after a crushing defeat by Juventus.
England left back Ashley Cole will miss holders Chelsea's Champions League Group E game at home to Shakhtar Donetsk on Wednesday because of a hamstring injury.
Shakhtar Donetsk led the way for the Champions League underdogs as they beat holders Chelsea 2-1 while former European champions Barcelona and Manchester United came from behind to maintain perfect starts on Tuesday.
Sevilla in semis as Wolves miss penalty.
AC Milan have been drawn to play Manchester United in what is the standout tie in next month's Europa League round of 16.
Defending champions Bayern Munich must face Diego Simeone's Atletico Madrid after they were drawn together in Champions League Group A alongside Salzburg and Lokomotiv Moscow.
Sevilla, winners of the Europa League for the past two years, will play Shakhtar Donetsk in this season's semi-final.
Cristiano Ronaldo delivered the knockout blow for Real Madrid in their aristocratic battle with AC Milan on Tuesday, as Arsenal, Chelsea and Bayern Munich maintained their own perfect Champions League starts.
Blames mid-week Champions League win against Juve for 'mental pressure'
Barcelona have decided to appeal UEFA's proposal to ban Andres Iniesta for one Champions League match for deliberately collecting a yellow card.
After Tuesday's 11-goal fireworks the matches are likely to be tighter in Wednesday's Champions League quarter-final first legs as Chelsea entertain Manchester United and Barcelona host Shakhtar Donetsk.
AS Roma midfielder Daniele de Rossi received a three-match ban on Friday for an off-the-ball incident in last week's Champions League match against Shakhtar Donetsk.
Chelsea have the chance to avenge their shattering penalty shootout defeat to Manchester United in the 2008 final after being drawn to play them in the quarter-finals of the Champions League on Friday.
Inter Milan goalkeeper Julio Cesar was called up by Brazil for the first time since the 2010 World Cup on Tuesday for next month's friendly away to France. The 23-man squad picked by coach Mano Menezes includes uncapped midfielders Jadson of Shakhtar Donetsk and Renato Augusto of Bayer Leverkusen.
Arsenal hope to complete a full set of English clubs going into the Champions League knockout phase on Wednesday though there could be a few anxious faces at The Emirates when they take on Partizan Belgrade.
Moroccan Yassine Bono denied Marcus Rashford, Bruno Fernandes, Mason Greenwood and Anthony Martial in either half of the match to keep the match alive
Zidane ruled out following in the footsteps of Alex Ferguson, who spent 26 years in charge of Manchester United.
Shakhtar Donetsk striker Maicon has been killed in a car crash, the Ukrainian club said on their website on Saturday.
Barcelona could be at full strength in Tuesday's Champions League clash at Shakhtar Donetsk despite the luxury of a 5-1 advantage from the quarter-final first leg, coach Pep Guardiola suggested on Monday.
Barcelona seized control of their Champions League quarter-final against Shakhtar Donetsk when an early Andres Iniesta strike paved the way for a 5-1 first-leg victory at the Nou Camp on Wednesday.
If two or more clubs are level on points at the end of the group stage, a number of criteria will be taken into consideration to decide the qualifiers for the next round, starting with the head-to-head record among the teams in question. It then goes to superior goal difference and then goals scored in those matches.
Barcelona and Shakhtar Donetsk became the first teams to reach the Champions League quarter-finals with contrasting wins over Arsenal and AS Roma, who both finished with 10 men, on Tuesday.
AS Roma needed a last-minute penalty from David Pizarro to win 2-1 at lowly Lecce in Serie A on Friday and boost their confidence ahead of Tuesday's Champions League clash with Shakhtar Donetsk.
Barcelona suffered a 2-1 defeat at Arsenal and AS Roma's miserable run continued with a 3-2 home loss to Shakhtar Donetsk in Champions League last-16 first-round matches on Wednesday.
A summary of the opening day's action in the UEFA Champions league on Tuesday.
IMAGES from the Champions League matches played on Tuesday
Round up of the Champions League matches played on Wednesday.
Brazilian Fernandinho's second-half equaliser earned Shakhtar Donetsk a 1-1 draw with Dynamo Kiev in the first leg of their UEFA Cup semi-final in Ukraine's capital on Thursday. Shakhtar's Olexandr Kucher will miss the second leg next week through suspension after being booked midway through the second half.
Hamburg SV and Werder Bremen stayed on course for an all-German UEFA Cup semi-final clash with 3-1 victories over Manchester City and Udinese respectively in their quarter-final, first legs on Thursday. Shakhtar Donetsk beat visitors Olympique Marseille 2-0 while Dynamo Kiev drew at Paris St Germain in a lacklustre goalless affair leaving open the possibility of a Ukrainian semi-final if the French clubs fail to put in improved performances.