World number two Carlos Alcaraz beat seventh seed Arthur Fils 6-2, 6-4 on Saturday to advance into his third Barcelona Open final, where the Spaniard will face Denmark's Holger Rune for the title.
Zverev's brother Mischa Zverev was also eliminated, going out 6-3, 6-1 to David Ferrer in the first round, while Kei Nishikori eased to a 7-5, 6-2 win over Taylor Fritz to secure a place in the third round.
Rafa Nadal's bid to get back to top form before the French Open suffered a setback when he crashed to a 6-4, 7-6(6) defeat to 13th-seeded Italian Fabio Fognini in the third round of the Barcelona Open on Thursday.
World No. 2 Carlos Alcaraz defeated Tsitsipas in the 2021 US Open and in last year's Miami Masters and Barcelona Open.
'It's such an honour to win this tournament, looking at all the names who have won it I'm very happy and proud that my name is also there now'
Kei Nishikori was crowned Barcelona Open champion for the second consecutive year after a hard-fought 6-4, 6-4 victory over surprise Spanish finalist Pablo Andujar on Sunday.
Rediff.com has this and a whole lot more exciting action from the week gone by, encapsulated in this photo feature.
The latest tennis rankings have been announced by the ATP and WTA
The World No 4 is unfazed by rankings drop before Madrid tournament and the French Open.