Holders Barcelona will play Premier League leaders Arsenal in the last 16 of the Champions League, 10 years after the sides faced each other in the final, following Monday's draw for the first knockout stage.
Last year's finalists Juventus will face-off against Bundesliga champs Bayern.
Napoli kept alive their hopes of advancing from Group C after Lorenzo Insigne, Victor Osimhen and Matteo Politano secured a 3-0 home win over Legia Warsaw.
Visitors Ajax had looked comfortable after former Southampton winger Tadic set up the first goal with a swerving cross before drilling home the second himself.
Mexico captain Andres Guardado said his side have become fearless after following up their hugely impressive win over world champions Germany by beating South Korea 2-1 on Saturday to take a huge leap towards topping Group F.
The Champions League group stages took on a less predictable look after Thursday's draw, helped by UEFA's decision to tweak the seeding system.
Celtic, who won Europe's premier club competition in 1967, set up a clash with Romanians Cluj in the next stage after a 2-0 win at Nomme Kalju completed a 7-0 aggregate rout of the Estonian champions.
Champions League competitors Schalke 04 have signed AC Milan midfielder Kevin-Prince Boateng on a four-year deal after the Ghana international passed his medical at the German club on Friday.
Former Brazil forward Ronaldo said on Wednesday he will try to get back into shape with an eye on coming out of retirement to play for North American second division club Fort Lauderdale Strikers.
Having knocked out Real Madrid with a 4-1 win at the Bernabeu in the previous round, Ajax came from behind to beat Juventus 2-1 in Turin and complete a remarkable 3-2 aggregate win in their quarter-final.
Manchester City beat Dynamo Kiev 3-1 during their UEFA Champions League round of 16, first leg match in Kiev on Wednesday.
Evergreen Francesco Totti, in his 22nd season with AS Roma, scored his first goal of the new campaign to give help them to a 3-1 win at Parma which maintained their 100 percent record in Serie A.
IMAGES from Europa League matches played on Thursday.
Midfielder Michael Carrick thinks Manchester United's summer signings have quickly settled at Old Trafford and will do their bit in helping the club challenge for major honours this season.
News of all that's transpired on and off the football field
Manchester United have completed the signing of PSV Eindhoven forward Memphis Depay on a four-year contract, the Premier League club said on Friday.
Ajax were joined by Young Boys, who stunned Dinamo Zagreb 2-1 away for a 3-2 aggregate win over the Croatians, and AEK Athens who scraped a 1-1 home draw with FC Vidi after a 2-1 win in the first leg in Hungary.
Dutch soccer star Robin van Persie returned to his home ground on Monday as he signed with Feyenoord Rotterdam hoping for a positive ending to his dwindling career.
A Romelu Lukaku hat-trick in a 4-1 win for Everton at Young Boys and a thrilling 3-3 draw between Celtic and Inter Milan.
Leicester City will play Barcelona, Celtic and Paris St Germain in this year's International Champions Cup (ICC), the Premier League leaders said on Tuesday.
Leicester City's win over Newcastle on Monday not only sent them five points clear of Tottenham Hotspur at the top of the Premier League, it effectively ended the challenge of Manchester City and Arsenal.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
Ten-man Premier League leaders Leicester City lost at title-chasing Arsenal, while La Liga pacesetters Barcelona crushed Celta Vigo and Juventus took over from Napoli at the top of Serie A by edging their rivals.
Manchester United and Tottenham Hotspur built hefty leads with emphatic away wins in their Europa League last 32 first-leg matches but AC Milan were held to a 2-2 draw at Red Star Belgrade as the competition resumed on Thursday.
Lionel Messi and Luis Suarez are both back for domestic duties as second-placed Barcelona resume their chase of La Liga leader Real Madrid with a tricky trip to red-hot Real Sociedad on Sunday. Barcelona, into the Champions League last 16 as Group C winners with a 2-0 win at Celtic on Wednesday, are four points behind Real Madrid who will host Sporting Gijon on Saturday without the injured Gareth Bale. "We have achieved our aim, which was to qualify as first of our group and now we need to turn our focus to La Liga," Barcelona centre back Javier Mascherano told www.fcbarcelona.com.
Pep Guardiola will return to the Nou Camp in the Champions League group stage after his new club Manchester City were drawn against his former Barcelona team on Thursday. The two sides were drawn in Group C alongside Borussia Moenchengladbach and former European champions Celtic in one of the toughest of the eight sections. Spanish coach Guardiola, who won the Champions League twice with Barca, faced the Catalans when he was in charge of Bayern Munich two seasons ago and suffered a 5-3 defeat in the semi-finals.
A summary of Thursday's matches in the Europa League.
Arsenal's inability to kill off the contest will be a frustration as that has been a hallmark of their recent form. They had won their previous 18 Premier League matches in which they scored first.
Tottenham manager Mauricio Pochettino has said Ajax have an unfair advantage because the whole of the Dutch league programme was postponed to help Erik ten Hag's side prepare.
Indian football hero of '80s, Chibuzor dies
FIFA president Gianni Infantino is hoping video replays will be used at the 2018 World Cup in Russia to help referees avoid serious mistakes during the tournament.
If Atletico Madrid's 2013 King's Cup triumph was a shock and their 2013-14 La Liga title a surprise, few would raise an eyebrow if Diego Simeone's ruthlessly efficient side were to win another major trophy.
Images from action in the Europa League matches on Thursday.
Photos from the UEFA Champions League matches played across Europe on Wednesday
Arsenal teenager Bukayo Saka scored his first goal for the club as they beat 10-man Eintracht Frankfurt 3-0, while Manchester United's 17-year-old Mason Greenwood secured a 1-0 win over FC Astana as the Europa League group stage began on Thursday.
Photos from the Champions League matches played across Europe on Tuesday
A summary of Tuesday night's matches in the UEFA champions League.
Belgian league leaders Antwerp secured a shock 1-0 win over Tottenham Hotspur and AC Milan extended their unbeaten run to 23 games as they won 3-0 against Sparta Prague in the Europa League on Thursday, while Arsenal cruised to a 3-0 win over Dundalk.
Barcelona have been frighteningly good at home this season, scoring 15 goals in three games at the Nou Camp.
Valencia sign Kondogbia on loan from Inter