Ole Gunnar Solskjaer's side, who had won their last ten away games in the Premier League, stay third on 27 points, a point behind second-placed Leicester.
Champions Liverpool are five points clear at the top of the Premier League after a 7-0 away hammering of Crystal Palace while Arsenal's troubles continued with a 2-1 defeat at second-placed Everton on Saturday.
A summary of Saturday's action in the Premier League.
Manchester City move a step closer to the Premier League title after a game in which both sides finished with 10 men.
Images from the Premier League matches played on Thursday.
Images from the English Premier League matches played on Sunday night
Manchester United won 2-1 at Crystal Palace to consolidate fourth spot.
Leicester City won at Arsenal for the first time in 47 years on Sunday, with substitute Jamie Vardy's late close-range header enough to secure victory in the Premier League at The Emirates.
Newcastle grabbed a point to leave City manager Pep Guardiola frustrated.
Daniel Sturridge's Liverpool career seemed to be heading for a premature end last season but the striker showed on Tuesday he may yet have an important role after taking his chance during a rare start in the Champions League win over Paris St Germain.
The gifted 23-year-old attacking midfielder is moving to Anfield from Germany's Hoffenheim, where he played since 2010, scoring 47 goals in 151 appearances.
Images from Saturday's action in the Premier League.
Arsenal's defence of the trophy ended with something of a whimper as Mikel Arteta's side struggled with repeatedly sloppy defending.
Images from the English Premier League matches played on Saturday.
Liverpool manager Brendan Rodgers has expressed his delight with Christian Benteke and Roberto Firmino after the forwards made their first-team debuts in the club's final warm-up match before the new Premier League season.
A summary of Saturday's matches in the FA Cup.
List of major transfers in the top Premier League ahead of the 2019-20 season (all transfer fees as reported by British media):
Eight wins and a draw in their last nine games had seen Leicester emerge as the closest pursuers of runaway leaders Liverpool but they went down 3-1 at the Etihad despite taking an early lead through Jamie Vardy. Images from the English Premier League matches played on Saturday.
Manchester United's Bruno Fernandes fired home a late penalty to rescue a point for the visitors in a lively 1-1 draw at Tottenham Hotspur in the Premier League on Friday.
However, one goal proved enough for City who picked up their sixth successive league win to move four points clear of Liverpool, who host Aston Villa later on Saturday, at the top of the standings.
Liverpool wrapped up a deal for Christian Benteke on Wednesday, luring the targetman to Anfield on a long-term contract.
Liverpool survived a late spell of Everton pressure to stretch their record unbeaten run in Merseyside derbies to 17 games
Lacazette fired the Gunners ahead in the eighth minute after poor defending by the home side before new signing Gabriel made it 2-0 in the 49th and Aubameyang put the icing on the cake with a superb shot into the top corner.
Joe Maguire was found guilty of repeated bodily harm, violence against public employees and attempted bribery. Sharman was found guilty of insult, repeated bodily harm and violence against public employees.
A late goal by substitute Charlie Austin gave relegation-threatened Southampton a thrilling 3-2 victory over Arsenal on Sunday in new Austrian manager Ralph Hasenhuettl's first home game.
IMAGES from the English Premier League matches played on Wednesday.
English Premier League matches have continued behind closed doors during the second lockdown announced on November 1. Supporters have not been allowed into sporting venues since the first lockdown was announced in March, barring a few exceptions.
Liverpool's Sadio Mane marked his return from injury with a late goal to break Norwich City's resistance and secure a 1-0 win on Saturday to extend his side's Premier League lead to 25 points.
England coach Roy Hodgson can give Wayne Rooney 'no guarantees' that he will always pick him for the national team and said the current crop of forwards he has to choose from is the best he has seen during his tenure.
Arsenal scored twice in the opening seven minutes and ended the match as a contest with a third in the 19th as they crushed Manchester United 3-0 to move above them into second place in the Premier League at the Emirates on Sunday.
High drama ensued during the English Premier League matches on Wednesday as Spurs manager Jose Mourinho was booked while Brighton stunned Chelsea via Alireza Jahanbakhsh's superb equaliser to deny the Blues victory. Here is all the EPL action in IMAGES from Wednesday's matches.
Tottenham's task was made all the more difficult two minutes before the interval when forward Son Heung-min was sent off
Images from the EPL matches played on Sunday
Tottenham Hotspur stormed back from 2-0 down to beat Burnley 4-2 in their FA Cup third-round replay on Wednesday despite resting their top striker in the once-fabled competition.
Manchester United kept up their impressive chase for a top-four spot with a comfortable 3-0 win at relegation-threatened Aston Villa in the English Premier League on Thursday. Relegation-threatened Bournemouth had a late goal disallowed by VAR as they had to settle for a 0-0 draw at home to Tottenham Hotspur.
Twelve months ago Liverpool were ripping up the record books on the way to their first English top-flight title for 30 years but defeat by Everton on Saturday left them mulling a host of far less flattering statistics.
A round-up of Saturday's action in the Premier League.
Burnley's seemingly doomed attempt to avoid relegation from the Premier League.
Manchester United survived a tense finale to beat West Bromwich Albion 2-1 at the Hawthorns on Sunday and close to within 11 points of Premier League leaders Manchester City.
French teenager Anthony Martial, having scored as a substitute on his Premier League debut in Manchester United's last game, added two more goals to earn his team a 3-2 win at Southampton on Sunday.
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