In-form Borussia Moenchengladbach struck three times in 14 minutes in the second half to floor champions Bayern Munich 3-1 on Saturday and inflict their first Bundesliga defeat of the season.
Ten of the 16 sides also reached the same round two seasons ago and, as usual, the big five leagues dominate with 13 clubs hailing from either the English, Spanish, German, French and Italian leagues.
Lionel Messi's knack for finding the net continued for an 18th consecutive league match as Barcelona restored their 13-point lead in La Liga.
Real Madrid's Cristiano Ronaldo may be on course for his worst domestic goal haul since 2010 but with two strikes against Bayern Munich in the Champions League quarter-final first leg on Wednesday he became the first player to score 100 goals in UEFA competitions.
A wrap of the football matches played across Europe over the weekend.
Bayern Munich must learn their lessons from a 2-0 Champions League defeat by Arsenal that saw the Germans advance to the last eight but fall well short of their own expectations, Bayern coach Jupp Heynckes said on Wednesday.
Bayern Munich winger Franck Ribery has been ruled out of their Champions League round of 16 second leg at home to Arsenal on Wednesday after picking up an ankle injury in the league on Saturday, the club said in a statement.
German midfielder Bastian Schweinsteiger is unlikely to play for Manchester United this season, manager Jose Mourinho said on Friday.
Zidane will come up against Guardiola for the first time as a manager when their sides meet in a blockbuster tie in the Champions League last 16 next February.
Real Madrid's Karim Benzema rescued his side again by scoring two late goals to snatch a 2-1 win at home to Elche in La Liga on Saturday and revive his side's hopes of catching leaders Atletico Madrid.
Having played second fiddle to Bayern Munich domestically all season Borussia Dortmund again dazzled on the European stage as they crushed Shakhtar Donetsk 3-0 for a 5-2 aggregate win that took them to the Champions League quarter-finals on Tuesday.
The Champions League rule which has denied Tottenham Hotspur a place in next season's competition because Chelsea won Saturday's final could be reviewed by UEFA's executive committee, president Michel Platini said on Wednesday.
News of all that's transpired on and off the football field
Prime Minister David Cameron savoured Chelsea's win over German club Bayern Munich in the Champions League final on Sunday after watching the deciding penalty shootout with German Chancellor Angela Merkel at a summit in the United States.
Long-serving Arsenal manager Arsene Wenger can do very little to salvage even pride from what looks like being another trophyless season after Tuesday's 3-1 Champions League home defeat by Bayern Munich.
The Bayern Munich juggernaut rolled on with a 3-1 first-leg win over an Arsenal side lacking confidence and ill-equipped to stop the German giants seizing control of their Champions League last 16 tie on Tuesday.
Arsenal midfielder Jack Wilshere says his team must take Chelsea's spirit into Tuesday's Champions League, last-16 first-leg clash with Bayern Munich if they are to keep alive their hopes of salvaging something from a mediocre season.
Bayern Munich demolished Schalke 04 4-0 with two goals from David Alaba to open a 15-point gap at the top of the Bundesliga on Saturday as champions Borussia Dortmund and Bayer Leverkusen slipped up.
French footballers Franck Ribery and Karim Benzema go on trial in Paris on Tuesday accused of paying for sex with a teenage call girl.
Angry Barcelona fans chanted for the resignation of the club president Josep Maria Bartomeu after captain Lionel Messi announced on Tuesday that he wished to leave the Catalan side.
Bundesliga champions Bayern Munich achieved record turnover figures for 2013/14 on Friday, matching their success on the pitch by breaking through the 500 million euros (398.05 million pounds) barrier for the first time.
Arsenal manager Arsene Wenger has hinted that he may be making a sensational summer swoop for Manchester United striker Wayne Rooney, who is said to be unsettled at the Old Trafford and had also handed a transfer request.
Coach Pep Guardiola, who will take charge of Bayern Munich next season, was convinced by the overall image of the German club and not lured by cash, Bayern CEO Karl-Heinz Rummenigge said on Thursday.
Borussia Dortmund midfielder Mario Goetze will miss Saturday's Champions League final against Bayern Munich due to a thigh muscle injury, the Bundesliga club said on Wednesday.
Second-placed Borussia Dortmund beat hosts Mainz 05 2-0 on Friday in coach Thomas Tuchel's return to his former club, ending their three-game winless run in the Bundesliga to close in on leaders Bayern Munich.
Images from football matches played across Europe over the weekend.
A stoppage-time goal from Branislav Ivanovic helped Chelsea become the first English club to win all three of UEFA's major trophies as they beat Benfica 2-1 in the Europa League final.
Bayern Munich coach Jupp Heynckes will sit on the coaching bench for a Bundesliga game for the last time when the champions meet his former club Borussia Moenchengladbach in the season finale on Saturday, and hinted on Monday that he might retire.
A round-up of Wednesday's action in the UEFA Champions League.
Bayern Munich cruised into a first all-German Champions League final when they routed Barcelona 3-0 at the Nou Camp on Wednesday to secure a crushing 7-0 aggregate success.
A selection of statistics surrounding Bayern Munich's 4-0 victory over Barcelona in the Champions League semi-final first leg on Tuesday.
Barcelona centre half Gerard Pique acknowledged his team were thoroughly second best as Bayern Munich romped to a 4-0 win in their Champions League semi-final first leg at the Allianz Arena on Tuesday.
Bayern Munich's 4-0 rout of Barcelona in a Champions League semi-final first leg on Tuesday was partly down to two goals that should have been chalked off, said assistant coach Jordi Roura.
Yet even without a transfer fee, Messi's colossal salary, reported to be the highest in world football, means very few clubs would be able to afford him.
Treble winners Bayern Munich edged past Eintracht Frankfurt 1-0 courtesy of a Mario Mandzukic volley on Saturday to equal their club record of 27 games without defeat as minnows Hoffenheim demolished Hamburg SV 5-1.
Barcelona forward Lionel Messi has recovered sufficiently from a hamstring strain to feature in Tuesday's Champions League semi-final first leg at Bayern Munich, sporting director Andoni Zubizarreta said on Monday.
The era when German teams always came out on top is over and Spain have replaced them as the dominant force in the world game, according to Barcelona defender Gerard Pique.
Reigning Spanish champions Real Madrid has been valued at $3.3 billion by Forbes magazine, ending the $3.2 billion worth Manchester United's nine-year reign at the top of the magazine's annual list of the most valuable football teams in the world. Check out Forbes' 10 most valuable soccer clubs in the world.
Xherdan Shaqiri scored one goal and set up three and substitute Mario Gomez notched a quick hat-trick as Bayern Munich, chasing a treble of titles, crushed VfL Wolfsburg 6-1 on Tuesday to move into the German Cup final.
Bayern Munich won their 22nd Bundesliga title in record time on Saturday by beating Eintracht Frankfurt 1-0 to open up an unassailable 20-point lead with six games left in the season.