With the Catalans shorn of three of their top forwards, all eyes will be on Griezmann in his first appearance at the Camp Nou since his 120-million-euro ($133 million) move from Atletico Madrid, and not least because Barca need a win to kickstart their season.
The hard-fought win took Zinedine Zidane's side on to 77 points after 34 games, seven clear of second-placed Barca who visit in-form Villarreal later on Sunday.
La Liga leaders Barcelona handed Real Madrid more hope in the title race as they drew 0-0 at Athletic Bilbao on Sunday, only avoiding defeat thanks to some outstanding saves by Marc-Andre ter Stegen.
Barcelona, Athletic Bilbao and the Spanish football federation face fines over politically-motivated whistles and banners during last season's King's Cup final at the Nou Camp, the Spanish government said on Monday.
In-form Luciano Vietto hit two second half goals as Villarreal, down to 10 men for the final 10 minutes, cruised to a 3-0 home victory over Deportivo La Coruna to go fifth in La Liga.
Champions Liverpool suffered a shock 1-0 defeat to lowly Burnley on Thursday, ending their 68 match unbeaten home record in the Premier League as their title defence continued to fade.
Barcelona have emerged as favourites to be crowned champions after one defeat in their last 22 Liga games.
The league said last week that the deal, called 'Boost La Liga', would strengthen its clubs and give them funds to spend on new infrastructure and modernisation projects as well as increasing how much they could spend on players' salaries.
Real are third in the league standings with 54 points after 28 games, two behind second-placed Atletico Madrid who visit Athletic Bilbao later on Saturday and nine points behind leaders Barcelona who play at Real Betis on Sunday.
The European Commission will begin disciplinary action against seven Spanish clubs including Real Madrid and Barcelona over possible illegal state aid, Spanish foreign minister Jose Manuel Garcia Margallo said on Monday.
Gary Neville was sacked as Valencia manager on Wednesday as the club brought an end to his fraught four-month spell in charge after the former England and Manchester United defender had delivered only three league wins.
The Catalans have kept five clean sheets in their last six games, which bodes well for their title run in.
Juergen Klopp's Europa League nightmare came true on Friday when his Liverpool side was drawn to meet former club Borussia Dortmund in next month's quarter-finals.
Images from the soccer matches played across Europe on Saturday.
The Catalans will not just be looking to extend their domestic hegemony, though, as they have spent a combined 250 million euros ($280 million) on a renewed bid to win the Champions League.
Espanyol secured a commanding lead in their King's Cup quarter-final tie against Sevilla when Felipe Caicedo, Sergio Garcia, with a penalty, and Lucas Vazquez scored in a 3-1 first-leg home win on Thursday.
Cristiano Ronaldo is angry with his recent record in front of goal but not anxious about when he will find the net next, Real Madrid coach Zinedine Zidane said on Friday.
De Jong is proud to join the likes of compatriots Ronald Koeman, Frank de Boer and Patrick Kluivert in heading to the Nou Camp, having dreamed of wearing Barca colours.
A sloppy Real Madrid were held 0-0 at home to Real Betis on Saturday in a further blow to their hopes of retaining the La Liga title.
Images from La Liga matches played on Monday.
Twenty-three-times Cup winners Athletic Bilbao were dumped out in sensational circumstances by tiny island side SD Formentera, who sneaked a 1-0 win at San Mames with a header by Alvaro Muniz deep in stoppage-time to reach the last 16 for the first time with a 2-1 aggregate victory.
Barcelona kept up the pressure on La Liga title rivals Atletico Madrid and Real Madrid when Lionel Messi struck from the penalty spot in a 1-0 win at Espanyol in Saturday's Catalan derby.
The rest of Barcelona's squad will have to do "a little bit more" to make up for the absence of five-times World Player of the Year Lionel Messi for the next three weeks, according to captain Andres Iniesta. The Argentina forward faces a spell on the sidelines after sustaining a groin injury in Wednesday's 1-1 La Liga draw with Atletico Madrid. "There's no question we are stronger with Messi," Iniesta told Cadena Cope radio ahead of Saturday's match at Sporting Gijon. "When these things happen we all have to give a little bit more.
Real play Athletic Bilbao while Barcelona visit Real Sociedad in fixtures that have often proved to be among their hardest away trips over the last decade.
Real Madrid have started the season flying with three wins from three games.
Real Madrid coach Carlo Ancelotti is confident Cristiano Ronaldo's three-match ban will be reduced to two so he can play in Saturday's La Liga game at home to Elche.
Barcelona will attempt to give Luis Enrique his 100th victory in his 125th game in charge of the team when they play at Athletic Bilbao in la Liga on Sunday. A former Barca player, the 46-year-old led them to a La Liga, King's Cup and Champions League treble in his first year in charge and the domestic double last season. The Catalans started the campaign with a 5-0 aggregate triumph over Sevilla in the Spanish Super Cup and a 6-2 victory over Real Betis in La Liga.
Neymar should return to Spain with renewed enthusiasm after leading Brazil to their first soccer gold medal at an Olympic Games, Barcelona defender Gerard Pique said. Neymar, who has scored 85 goals in 141 games in his three seasons at Barcelona, was given permission to stay in Brazil until after international games early next month. "I think it's a good decision to grant him (Neymar) that," Pique told El Mundo Deportivo. "He has earned it.
Spain coach Luis Enrique promised evolution rather than revolution when he took charge of the national side following their disastrous World Cup campaign this year when they were eliminated in the round of 16.
Villarreal set up a King's Cup semis against Barca after Gerard Moreno gave them a 1-0 win
A round of Saturday's matches in Series A, La Liga and Bundesliga.
Lionel Messi scored one penalty and missed another as Barcelona beat Real Valladolid 1-0 on Saturday to open up a seven-point lead at the top of La Liga.
Real coach Julen Lopetegui has come in for fierce criticism this season, having presided over a run of five games without a win -- the team going eight hours and one minute without scoring -- before Tuesday's unconvincing 2-1 triumph over Viktoria Plzen that saw the team whistled off the pitch by their own fans.
The Manchester United keeper let a tame shot from Cristiano Ronaldo through his arms for Portugal's second goal on Friday and has been criticised in Spain for his badly positioned defensive wall when Ronaldo struck the late equaliser.
The victory takes Barcelona up to fourth with 10 points after six games, one point behind surprise leaders Granada, Athletic Bilbao, who visit Leganes on Wednesday, and Real Madrid ahead of their game at home to Osasuna the same night.
"The intention is to sell him, but there's no offers forthcoming," read the front page of Marca, accompanied by a picture of the 29-year-old Bale looking sullen.
Chelsea agreed a deal to sign Real Madrid striker Alvaro Morata, subject to the Spain international agreeing personal terms and passing a medical.
Midfielder Santi Cazorla gave the home side the lead in the fourth minute of the game, which was rescheduled due to Real's participation in last month's Club World Cup, by bending a wonderful shot into the bottom corner.
Barcelona's stuttering title bid suffered another setback when they lost 2-1 at home to Valencia on Sunday, while Atletico Madrid moved level on points with the La Liga leaders after a comfortable win over Granda.
Lionel Messi was lauded by opposition supporters on Sunday after he scored an outstanding hat-trick in Barcelona's 4-1 win at Real Betis, which put the Catalans 10 points clear at the top of La Liga with 10 games remaining.