Manchester City's barnstorming start to the English soccer season, producing five straight wins, is in danger of becoming a fading memory after consecutive defeats by West Ham United and Tottenham Hotspur allowed Manchester United to knock them off the top of the table.
Liverpool boss Juergen Klopp has beaten Manchester United only twice in his career and never at Old Trafford -- his worst record against any Premier League side.
Brighton and Hove Albion scored late to earn a 1-1 draw at Crystal Palace. Sheffield United and Fulham also drew 1-1 as both teams picked up their first points.
Gerard Delofeu's late goal earned Everton a deserved 1-1 draw at Premier League leaders Arsenal on Sunday after Mesut Ozil's strike seemed set to seal three points for the home side.
Bitter rivals Arsene Wenger and Jose Mourinho had wildly contrasting afternoons on Saturday as Arsenal went top of the Premier League and champions Chelsea lost again with their manager being sent off.
Arsenal's defence of the trophy ended with something of a whimper as Mikel Arteta's side struggled with repeatedly sloppy defending.
Champions Liverpool were ripped apart 7-2 at Aston Villa and Manchester United were humiliated 6-1 at home by Tottenham Hotspur on Sunday in one of the most astonishing days of Premier League results.
Sergio Aguero scored five times in 20 minutes including an eight-minute hat-trick as Manchester City came from behind to thrash Newcastle United 6-1 and go back to the top of the Premier League table on Saturday.
Leaders Liverpool faltered in the English Premier League title race for the second time in six days as they were held to a 1-1 draw at West Ham United.
However, one goal proved enough for City who picked up their sixth successive league win to move four points clear of Liverpool, who host Aston Villa later on Saturday, at the top of the standings.
Arsenal substitute Pierre-Emerick Aubameyang scored twice in three minutes and captain Mesut Ozil played a starring role as they extended their winning run with a 3-1 victory over Leicester City in the Premier League on Monday.
Tottenham manager Mauricio Pochettino has said Ajax have an unfair advantage because the whole of the Dutch league programme was postponed to help Erik ten Hag's side prepare.
There is still a long way to go, with a young Ajax side sure to present a formidable obstacle to a Spurs squad shorn of leading strikers Harry Kane and Son Heung-min.
Arsenal will reportedly play Chelsea in a fourth-round Capital One Cup match after winning 4-3 on penalties against West Bromwich Albion on Wednesday at The Hawthorns.
The momentum that swept Leicester City away from relegation last season continued unabated at West Ham United on Saturday as their 2-1 win left them top of the Premier League.
Liverpool needed two extra-time goals to beat NottsCounty 4-2 at Anfield on an eventful night for the Premier League clubs in the League Cup second round on Tuesday.
The brilliance of Chelsea's Eden Hazard ended Liverpool's 100 percent start to the season as Maurizio Sarri's side enjoyed a 2-1 win at Anfield in the League Cup third round on Wednesday.
Champions Manchester United travel to Swansea City for their first Premier League match under new manager David Moyes, while Manuel Pellegrini's Manchester City are at home to Newcastle United on August 17.
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Cristiano Ronaldo shows no signs of flagging as he approaches his mid-30s but there are plenty of other worries for a team with an ageing central defence and a number of players struggling for form.
Leicester City's Jamie Vardy is banned from taking part in shooting drills at the training ground, the prolific striker revealed, because manager Claudio Ranieri wants him to rest his legs for Premier League matches.
Brief reports of English Premier League matches on Saturday:
After Wolves missed several chances in the first half, Raul Jimenez pounced in the 61st minute to break the deadlock with his second goal of the season.
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Images from the English Premier League matches played on Saturday
Chelsea to host Burnley in Premier League season ope
Images from the English Premier League matches played on Wednesday.
A preview of the line-up action in the English Premier League
Liverpool's James Milner's converted a penalty on the stroke of half-time and Sadio Mane added a late second goal to secure a hard-fought 2-0 victory at Crystal Palace in the Premier League on Monday.
There will be no seismic shifts in the balance of the world's richest football competition if the first weekend of the new Premier League season is anything to go by.
Chelsea manager Antonio Conte has said that the League Cup will provide an opportunity for him to assess the development of the youngsters in his squad.
Images from Saturday's action in the Premier League.
Liverpool's bandwagon rolled on as they crushed Merseyside rivals Everton 5-2
Images from the English Premier League matches played on Saturday
Leicester City continued to do their best Houdini impression on Saturday as they escaped the Premier League drop zone for the first time since November while Manchester City went up to second spot with a thrilling win.
Before the game, a few protesters handed out fliers outside the stadium where Man City played local outfit Kitchee.
Cesc Fabregas and Branislav Ivanovic struck late goals to earn improving champions Chelsea a 2-1 victory at Southampton in the Premier League on Saturday.
Holders and Premier League leaders Arsenal will be at home to Championship (second tier) Burnley in the fourth round of the FA Cup after most of the big guns avoided top flight opponents in Monday's draw.
Champions Manchester United's hopes of retaining their English Premier League title suffered another major setback on Saturday when they were beaten 1-0 at Old Trafford by a composed Newcastle United.
Shorn of European excitement and with only a remote hope of winning the Premier League, Manchester United manager Louis Van Gaal wants the FA Cup to garnish his first season in charge.