Holders Chelsea made light of their off-pitch problems to reach the Champions League quarter-finals by beating Lille 2-1 away on Wednesday to complete a 4-1 aggregate victory.
The Gunners' only league defeat of the campaign was in September away to one of England's traditional top-six clubs, Manchester United, drawing criticism that their strong start to the season was based on wins against lesser opposition.
Team doctor Rodrigo Lasmar told reporters that while a scan was needed to confirm the exact diagnosis, he did not think the injury to Neymar's adductor muscle would keep him out long and Neymar confirmed that early diagnosis.
With United unable to sign a replacement, the pressure will be on 21-year-old England forward Marcus Rashford to deliver the goals in a more central role than he has previously operated in.
Following is a match by match look at the English Premier League's weekend fixtures
De Rossi, who turned 36 on Wednesday, led Roma for the final time in a 2-1 victory over Parma at the Stadio Olimpico in May and finished his stint in the Italian capital with 616 appearances in 18 years.
News of all that's transpired on and off the football field
IMAGES from the English Premier League matches played on Saturday
News of all that transpired on and off the football field
News of all that transpired on and off the football field.
The result leaves Arsenal in fifth place on 15 points, two behind Leicester City and Chelsea, while Sheffield United moved into ninth on 12 points.
PSG have never reached the semi-finals of the Champions League
Real Madrid will be without forward pair Cristiano Ronaldo and Gareth Bale, midfielder Toni Kroos and defender Pepe for Tuesday's UEFA Super Cup encounter with Sevilla in Trondheim, Norway.
Despite Barcelona's exit from the Champions League at the quarter-final stage, coach Luis Enrique said their victory over Sevilla in the King's Cup on Sunday had capped a "fantastic" season.
IMAGES from the EPL match played between Arsenal and Newcastle on Monday
Arsenal substitute Pierre-Emerick Aubameyang scored twice in three minutes and captain Mesut Ozil played a starring role as they extended their winning run with a 3-1 victory over Leicester City in the Premier League on Monday.
Wenger departed in May after 22 years in charge having endured a barrage of criticism in the latter part of his reign for a tactical approach that resulted in 14 seasons without a Premier League title.
Sevilla's devastating display to dispatch Malaga 4-1 on Saturday put them in their highest league position after 16 games for a decade and left little doubt that hiring coach Jorge Sampaoli to succeed serial winner Unai Emery was the right choice.
Arteta, who will lead City in their Champions League opener against Olympique Lyonnais on Wednesday because manager Pep Guardiola is suspended, also said that his team were better placed to challenge for top European honours this season.
Eden Hazard scored twice and created a third to steer Chelsea to a 4-1 victory over London rivals Arsenal in the Europa League final in what looks likely to be the Belgium winger's final game for the Blues.
There will be no seismic shifts in the balance of the world's richest football competition if the first weekend of the new Premier League season is anything to go by.
Atletico Madrid substitute goalkeeper Antonio Adan saved three penalties before blasting home the winning spot-kick as the Europa League champions edged out Arsenal after the sides drew 1-1 in their International Champions Cup opener in Singapore on Thursday.
IMAGES from the English Premier League matches played on Sunday.
News of all that's transpired on and off the football field
Holders Sevilla swept into a second consecutive Europa League final.
Arsenal enjoyed a 3-0 win in Azerbaijan against Qarabag in the Europa League on Thursday and AC Milan beat Greece's Olympiakos Piraeus 3-1 but Sevilla suffered a shock defeat by Russians Krasnodar.
Olympique de Marseille were the fall guys on a hectic opening night of Europa League group stage action as German club Eintracht Frankfurt returned from the south of France with a surprise 2-1 victory on Thursday.
Real Madrid warmed up for their crunch meeting against Barcelona by thrashing Sevilla 4-0 and coach Zinedine Zidane believes his team "can do great things" if they match the performance they produced against Unai Emery's side.
"This was one of the reasons why I took this opportunity. To train with all these personalities and this talent."
While Spurs play Inter Milan at home in Champions League on Wednesday, on Thursday, Arsenal face a long trip to Ukraine to play Vorskla Poltava in the Europa League, needing a victory to consolidate first place in the group.
Champions Paris St Germain provisionally moved back to the top of Ligue 1 as Adam Lang's own goal, Edinson Cavani's penalty and a second-half header from Lucas Moura downed promoted Dijon 3-0 at the Parc des Princes on Tuesday.
News of all that's transpired on and off the football field.
News of all that's transpired on and off the football field.
Third-placed Leicester go to Hodgson's sixth-placed Crystal Palace on Sunday
A round-up of Sunday night's matches in the Premier League.
Arsenal's young guns continued to shine as they dismantled Standard Liege 4-0 on a hectic night of Europa League action that produced a full house of Spanish victories on Thursday. A summary of the matches.
Outgoing Valencia coach Cesare Prandelli was fiercely criticised on Saturday for 'giving up' on the ailing Spanish giants and for looking for excuses to walk out on the team as they hover above the relegation zone.
Here are five talking points from the weekend's action:
Manchester City begin a crucial week in the Premier League title race when they host Arsenal at the Etihad on Sunday.
News of all that's transpired on and off the football field