The Portugal is in New Jersey in preparation for the FIFA World Cup starting in about a week, but the country is facing problems over Cristiano Ronaldo's fitness.
Barca are now second on 66 points, two behind Real who have a game in hand as they chase a first title triumph since 2012.
Champions Liverpool are five points clear at the top of the Premier League after a 7-0 away hammering of Crystal Palace while Arsenal's troubles continued with a 2-1 defeat at second-placed Everton on Saturday.
Leaders Porto suffered a shock 2-1 defeat at Famalicao as Portugal's Primeira Liga became the latest league to return to action following the coronavirus stoppage on Wednesday.
A wounded Portugal, still smarting from a 4-0 defeat by Germany, are fervently hoping that talismanic forward Cristiano Ronaldo is fit when they take on the United States in their second World Cup Group G game on Sunday.
Portugal coach Paulo Bento suggested the referee was favouring Germany after his side had a penalty awarded against them and a player sent off in their 4-0 World Cup defeat on Monday.
Germany eased past 10-man Portugal 4-0 in their World Cup Group G match at Arena Fonte Nova in Salvador. Photos from the match.
Liverpool manager Brendan Rodgers refused to criticise defender Kolo Toure after his glaring error gifted West Bromwich Albion striker Victor Anichebe an equalising goal in their 1-1 Premier League draw on Sunday.
Reactions to Liverpool's Premier League triumph, their first league title since 1990:
Real Madrid may have strolled into the Champions League last 16 with a 4-1 win at home to Galatasaray on Wednesday but coach Carlo Ancelotti levelled some sharp criticism at centre backs Sergio Ramos and Pepe after the game.
Cristiano Ronaldo and Lionel Messi will resume their perennial battle to be crowned the world's best footballer after they headed the shortlist of 30 players for the 2016 Ballon d'Or announced on Monday.
News of all that's transpired on and off the football field
Images from Saturday's action in the Premier League.
Spain international goalkeeper Pepe Reina has left Liverpool for a season-long loan at Serie A club Napoli, but said in an open letter to fans of the five-times European champions it was not his decision to leave Anfield.
Liverpool goalkeeper Pepe Reina said the 10-match ban given to his team mate Luis Suarez for biting an opponent was 'absurd' and 'excessive'.
Spain international goalkeeper Pepe Reina has left Liverpool for a season-long loan at Serie A club Napoli, but said in an open letter to fans of the five-times European champions it was not his decision to leave Anfield.
An estimated 10,000 Napoli supporters, including the team's most famous player Diego Maradona, are expected to make the trip to the Spanish capital for the first competitive meeting with Real Madrid since the 1987.
Robin van Persie's late penalty earned below-par Manchester United a 2-1 victory over 10-man Liverpool in an emotionally-charged Premier League clash at Anfield and champions Manchester City were held to a 1-1 home draw by Arsenal on Sunday.
IMAGES from Champions League matches played on Tuesday.
Real Madrid romped to a 4-1 win at tiny Eibar on Saturday, provisionally returning to the top of La Liga, despite the absence of Gareth Bale and Cristiano Ronaldo for Zinedine Zidane's side.
Lionel Messi scored his maiden goal for Paris St Germain in Tuesday's 2-0 Champions League victory against Manchester City.
Rediff.com looks at the five best goals from the concluding round in the league stage.
The 24 sides through from the group phase join the eight third-placed finishers in the Champions League in Monday's draw, including Manchester United and Ajax Amsterdam.
Raheem Sterling struck twice as the Premier League champions Manchester City beat Crystal Palace 3-1 at Selhurst Park on Sunday to stay within two points of leaders Liverpool.
Rank outsiders Iceland enjoyed a superb big-stage debut as they clinched a shock 1-1 draw against Euro 2016 Group F favourites Portugal on Tuesday.
Real Madrid closed to within three points of La Liga leaders Barcelona and Atletico Madrid at the halfway stage of the season when a Pepe header secured a laboured 1-0 win at mid-table Espanyol on Sunday.
Portugal's Silvestre Varela scored a dramatic 87th-winner to give his side a 3-2 win over Denmark in a pulsating Euro 2012 Group B match on Wednesday.
Mario Gomez thumped in a superb 72nd-minute header to give Germany a 1-0 victory over Portugal after they had been frustrated for long periods of a cagey Euro 2012 Group B match on Saturday.
Defiant 10-man Porto upset Juventus to reach the Champions League quarter-finals on away goals after a 4-4 aggregate draw despite losing 3-2 to the Italians following extra time in a thrilling clash that went to the wire on Tuesday.
Arsenal slumped to a last-gasp 2-1 Premier League defeat at relegation-threatened Brighton & Hove Albion on Saturday in a blow to the London club's chances of securing European football next season. Watford's Craig Dawson grabbed a stoppage-time equaliser with an overhead kick to earn his side a 1-1 draw with Leicester City on Saturday and a vital point in their battle for Premier League survival.
Papiss Cisse scored both goals as Newcastle United continued their surprise push for a top-four finish in the Premier League on Sunday with a 2-0 victory over Liverpool, who had keeper Pepe Reina sent off late on.
Any sliver of a doubt over whether Cristiano Ronaldo would lead Portugal into the Euro 2016 was erased on Tuesday when he was named in their 23-man squad for the finals.
'In Angamaly Diaries, dreams, kinks, small corruptions, cheap lives, and hopes are all given their due and that attitude frees us up to believe that perhaps there is more good than bad in the sum total of us.' 'This is a coming-of-age tale taken straight out of a diary written in blood,' says Sreehari Nair.
Striker Fabio Quagliarella scored his first goal for a year to help Juventus to a 2-0 win over lowly Novara in Serie A on Sunday while Inter Milan's revival continued with a 1-0 win at Cesena.
Cristiano Ronaldo netted his fifth La Liga hat-trick of the campaign as Real Madrid brushed off Pepe's 44th-minute dismissal to secure a crushing 6-2 victory at Sevilla and move back above Barcelona to the top of the standings on Saturday.
Clint Dempsey pounced for an 85th-minute winner as Fulham beat Liverpool 1-0 in a dramatic Premier League match at Craven Cottage on Monday after a rare mistake from keeper Pepe Reina.
UEFA has thrown out protests made by Real Madrid and Barcelona against each other following their ill-tempered Champions League semi-final first leg last week.
A summary of Sunday's Premier League matches
Argentina got their World Cup qualifying campaign off to the perfect start on Thursday when Lionel Messi's early penalty gave them a 1-0 win over Ecuador in a lacklustre match in Buenos Aires.
Portugal, who missed a spot kick given thanks to the video assistant referees 16 minutes into the match, were awarded a second penalty after 104 minutes when Miguel Layun handled the ball.