Manchester City suffered from deja vu as Luis Suarez's double gave Barcelona a 2-1 first leg lead in a Champions League last 16 tie at the Etihad although Lionel Messi's late penalty miss left the door ajar on Tuesday.
Images from the UEFA Champions League matches played on Tuesday.
News of all that's transpired on and off the football field
Images from EPL matches played on Tuesday
VfL Wolfsburg reached the Champions League last 16 and dealt a knockout blow to Manchester United with a 3-2 victory to claim top spot in Group B and condemn their opponents to the Europa League on Tuesday.
Aaron Ramsey scored a hat-trick on Saturday as Arsenal thrashed Everton 5-1 in the Premier League at the Emirates with a display of free-flowing football that the Gunners have sorely lacked away from home this season.
Harry Kane's magical season continued on Saturday as he celebrated his first senior England call-up with his first Premier League hat-trick.
A summary of all the Champions League matches played across Europe on Wednesday
Following is a match by match look at the English Premier League's season-opening weekend fixtures:
Chelsea's Diego Costa continued his stunning start to life in the Premier League with a hat-trick in a 4-2 comeback win over Swansea City on Saturday that left champions Manchester City staring up the table after a 2-2 draw at Arsenal.
Cristiano Ronaldo scored twice in his 150th European appearance to give Real Madrid a 3-1 victory at Borussia Dortmund, their first against them in Germany, and make it two wins out of two matches in their Champions League Group H.
De Boer, who lasted only 77 days as Crystal Palace manager after losing his first four league games in charge with no goals scored, said in an interview on BT Sport that it was "a pity" Mourinho was Rashford's manager because he was not getting enough chances.
Former Arsenal striker Ian Wright has launched a scathing attack on the club's manager Arsene Wenger, saying he could not make a case for the Frenchman to extend his reign beyond this season.
Arsenal maintained their challenge for a first trophy in nine seasons when they beat Liverpool 2-0 at the Emirates Stadium to open up a five-point lead at the top of the Premier League on Saturday.
Spoils were shared in two huge Premier League derbies, Chelsea's cracking start continued with a 3-0 win over Aston Villa and Wayne Rooney produced a Jekyll and Hyde display in a nervy Manchester United victory on Saturday.
Spoils were shared in two huge Premier League derbies, Chelsea's cracking start continued with a 3-0 win over Aston Villa and Wayne Rooney produced a Jekyll and Hyde display in a nervy Manchester United victory on Saturday.
There will be plenty of tension in the air in North London on Wednesday when out-of-sorts Arsenal face Borussia Dortmund seeking to qualify from the Champions League group stage for the 15th successive season.
A round-up of the World Cup qualifying matches played on Friday.
A summary of Tuesday's group matches in the UEFA Champions League.
Wayne Rooney struck with a 74th-minute free kick to give England a 1-0 win over 10-man Estonia in a Euro 2016 Group E qualifier on Sunday and move to within six goals of Bobby Charlton's record tally of 49.
Spain started their World Cup qualifying campaign with a crushing 8-0 win over Liechtenstein, laying down a marker in Group G with a ruthless second-half display on Monday.
Manchester City's Sergio Aguero scored a hat-trick as coach Pep Guardiola maintained his 100 per cent record at the club with a commanding 4-0 victory against Borussia Moenchengladbach in their rearranged Champions League Group C opener on Wednesday.
Barcelona lost ground on La Liga leaders Real Madrid when their 11-match winning streak was snapped by Malaga, while Premier League pacesetters Chelsea dropped points at home to Burnley. Bayern Munich enjoyed a second-successive goalrush in the Bundesliga after routing Paderborn 6-0 while AS Roma lost ground to Serie A leaders Juventus after yet another draw. This and more from the happenings in the world of football over the weekend.
Photos from the Euro 2016 qualifying matches played on Sunday.