The Indo-French pair beat Russia's Alla Kudryavtseva and Slovenia's Katarina Srebotnik 6-4, 4-6, 10-8 in a first round match.
Djokovic will need to win in Tokyo and then the US Open later this year to achieve the feat that has so far only been accomplished by Steffi Graf in 1988.
American twins Bob and Mike Bryan fell short in their bid to capture a calendar-year Grand Slam when they lost to Czech Radek Stepanek and India's Leander Paes in the men's doubles semi-finals.
World Championships bronze medallist Sen had earlier advanced to the men's singles semi-finals after his opponent Lu Guang Zu of China gave a walkover.
World number one Kento Momota was stunned by number 38 South Korea's Heo Kwanghee on Wednesday, going down 15-21, 19-21 and looking visibly despondent at each lost point in his first round match at the Olympics, on Wednesday.
Milestones in the progress of Chinese women's tennis after Li Na, the first Asian to win Grand Slam singles titles, announced her retirement from the sport on Friday.
The absence of double Olympic medallist P V Sindhu, London Games bronze medallist Saina Nehwal and men's doubles pair of Chirag Shetty and Satwiksairaj Rankireddy also hurt India's prospect as the team cut a sorry figure at the team-tournament.
DeAnna Price threw 77.54 metres with her third attempt as she took advantage of the absence of four-times world champion Anita Wlodarczyk who was sidelined with injury.
Indian tennis ace Sania Mirza and her Chinese partner Jie Zheng cruised into the quarter-finals of the women's doubles at Flushing Meadows.
A subdued Serena Williams recovered from a sluggish start to beat China's Zheng Jie 6-7, 6-2, 9-7 in a marathon Wimbledon third-round match on Saturday.
Sen became only the third men's singles player after Prakash Padukone and Pullela Gopichand to reach the final
Venus Williams, Coco Gauff pair up to play doubles at French Open.
Commonwealth Games bronze medallists Ashwini Ponnappa and N Sikki Reddy scored a stunning straight games victory over world No. 18 Li Wenmei and Zheng Yu to make it to the second round in the women's doubles at the US $350,000 India Open, in Delhi, on Tuesday.
Rediff.com brings a selection of the week's best photographs from the sports world.
Menu included selection of traditional appetizers, double boiled bean curd soup, stewed porcini, pancake with vegetable.
Luis Suarez scored a hat-trick, including an exquisite second goal, as Barcelona strolled into the Club World Cup final with a 3-0 win over Asian champions Guangzhou Evergrande on Thursday.
The sixth seed and world No. 6 Indian needed 42 minutes to get the better of Beiwin Zhang of the United States, ranked eight places below her, 21-14, 21-17.
While many Western countries, including the United States, Britain and Australia, are diplomatically boycotting the Winter Olympics over China's human rights record, Putin will join a number of Beijing-friendly leaders at the Games.
Caroline Wozniacki resisted a sizzling baseline display from China's Zheng Jie to reach the semi-finals of the Indian Wells WTA tournament with a hard-fought 6-4, 4-6, 6-1 victory on Wednesday.
The 23-year-old, who this week became the first Australian woman to reach the top of the rankings since 1976, must survive a rough-looking path if she is to claim back-to-back Grand Slams having won her first at this month's French Open.
Naomi Osaka faces Zheng before possible meeting with Coco Gauff
Bethanie Mattek-Sands and her partner Lucie Safarova won their first Grand Slam women's doubles title
Chinese captain Zheng Zhi was caught up in the goal action when he made his Celtic debut against the club's bitter rivals Rangers in a 2-1 defeat on Sunday in the Scottish Premier League (SPL).
A summary of sports events and persons who made news on Saturday
Images from Day 7 of the 2022 French Open at Roland Garros in Paris on Saturday.
Sania Mirza and Martina Hingis advanced to the second round of the Wimbledon Championships, defeating the duo of Saisai Zheng and Zarina Diyas in the opening round on Wednesday night. The top seeded Indo-Swiss pair defeated the Chinese-Kazakh team 6-2, 6-2.
India's Leander Paes and Rohan Bopanna breezed into the quarter-finals and pre-quarter-finals of the men's and mixed doubles respectively at Wimbledon on Monday, but there was bad news on the Indian challenge in the women's doubles as Sania Mirza and Liezel Huber exited in the third round.
Milestones in the progress of Chinese women's tennis after Li Na won the final of the French Open on Saturday.
China was the first country to export such sensitive equipment to Pakistan
China's hopes of a first grand slam finalist were crushed by two of the greats of the women's game on Thursday but Li Na and Zheng Jie's brilliant Australian Open run marked another step in the country's inevitable rise.
A summary of the first day's play at the US Open.
Images from day ten of the 2010 Australian Open Grand Slam tennis tournament in Melbourne, on Wednesday.
Rising player Lakshya Sen went down to Denmark's Hans-Kristian Solberg Vittinghus
It was Novak Djokovic's first match this year after his Australian Open hopes were dashed when he was deported following an 11-day saga revolving around his decision not to have a COVID-19 vaccination.
World number one Ash Barty delighted the Memorial Drive crowd by breezing through to the Adelaide International semi-finals with a comfortable 6-3, 6-4 victory over Sofia Kenin on Friday.
Twice winner Serena Williams reached the Wimbledon final for the fourth time and third against sister Venus on Thursday with a 6-2, 7-6 victory over Chinese wildcard Zheng Jie on Centre Court.
Sania Mirza won her second title in a row as she lifted the China Open trophy with Cara Black, demolishing the challenge of Vera Dushevina and Arantxa Parra Santonja in straight sets, in Beijing on Saturday.
Indian tennis ace Sania Mirza and new partner Jie Zheng made a winning start in the women's doubles at the US Open.
Serena and Venus Williams lost 3-6, 6-4, 6-2 to former champions Yan Zi and Zheng Jie in the quarter-finals.
Indian tennis ace Rohan Bopanna and his Canadian partner Gabriela Dabrowski of Canada produced a spirited fight back to win 6-4, 5-7, 10-3 and book their place in the quarter-finals of the mixed doubles event at the season-opening Australian Open in Melbourne on Tuesday.