A round-up of Sunday's matches in La Liga, Serie A and Bundesliga.
Alexis Sanchez hit a hat-trick as Barcelona swept aside Elche 4-0 to return to the top of La Liga on goal difference ahead of Atletico Madrid on Sunday.
Juve forward Cristiano Ronaldo had an unusually quiet game after scoring a hat-trick against Atletico in last year's competition, although he came within inches of grabbing a last-gasp winner when he sent a shot just past the far post.
Last-minute starter Adrian Ramos scored a first-half header to give Borussia Dortmund a 1-0 victory over Sporting on Wednesday and earn a spot in the knockout stage of the Champions League with two Group F matches to spare.
Spain started their World Cup qualifying campaign with a crushing 8-0 win over Liechtenstein, laying down a marker in Group G with a ruthless second-half display on Monday.
Photos from the Champions League matches played across Europe on Tuesday
Barca dominated possession and Luis Suarez had several early chances but it was Villarreal who took the lead with Denis Cheryshev redirecting a Mario Gaspar shot past keeper Claudio Bravo on the half hour.
Spain strolled to a 4-1 win at home to Israel, while Italy survived some first-half scares on the way to a 2-0 win and Ukraine registered a 1-0 home win over Ukraine in an action-packed game.
Sevilla stayed firmly on course for a second consecutive Europa League crown when an Aleix Vidal double and a Kevin Gameiro strike secured a thumping 3-0 win at home to Fiorentina in their semi-final first leg on Thursday.
From heroes to zeros and back again, Leicester City's remarkable rollercoaster ride took another twist as a superb 2-0 victory over Sevilla put them in the quarter-finals of the Champions League on Tuesday.
Cristiano Ronaldo ensured Atletico Madrid fans will have bitter memories of the last local derby at the Vicente Calderon stadium by scoring a hat-trick in a 3-0 win for La Liga leaders Real Madrid on Saturday. Ronaldo's deflected free kick put Real in charge in the 23rd minute in the first meeting of the teams since the Champions League final in May. The prolific Portuguese killed off Atletico's resistance by winning and converting a penalty in the 71st minute and capped a harrowing night for the home side by tapping in the third in the 77th.
News of all that's transpired on and off the football field
Photographic summary of the football matches played across Spain, Italy and France
Images from the Europa League matches played on Thursday
News of all that's transpired on and off the football field