The 36-year-old Mary Kom triumphed 5-0 against Thailand's Jutamas Jitpong, a spunky boxer who kept the veteran on her toes with an aggressive approach but just didn't connect enough.
Mary Kom fought back in the final three minutes but that was not enough to get the judges' nod.
Both the boxers stuck to a defensive approach but Rani was the more accurate of the two.
The 36-year-old Manipuri has been an ambassador of the sport not just in India but also the world over
India had delivered its best ever Asian Championship performance in the 2019 edition in Thailand, claiming 13 medals, including two gold, four silver and seven bronze.
A summary of sports events and persons who made news on Wednesday.
A summary of sports events and persons who made news on Tuesday
Mary Kom defeated Chinese Taipei's Meng-Chieh Pin in a split verdict in the quarter-finals to make the last four stage of the light flyweight (48kg) category.
A summary of sports events and sports persons, who made news on Monday
Sanjeet Kumar won a gold medal in the 91 kg weight category at the Asian Boxing Championships.
Indian women boxers failed to secure a single Olympic quota berth at the AIBA World Championships after Pooja Rani (75kg) bowed out.
Sonia Lather (57kg) stood just one win away from ending India's six-year-old gold medal drought at the AIBA Women's World Boxing Championship as she advanced to final after outpunching Kazakhstan's Aizhan Khojabekova in the last-four stage in Astana, Kazakhstan on Thursday. The 24-year-old Sonia, who is a 2012 Asian Championships silver-medallist, defeated Khojabekova 3-0 to set up a clash with Italian Alessia Mesiano, who got the better of Bulgaria's Denitsa Eliseeva by a similar margin. The lone Indian left in the fray, Sonia was quick off the blocks against her rather sloppy rival. Combining right hooks with power-packed jabs, Sonia threw Khojabekova off balance on more than one occasion. Khojabekova was mostly clueless when it came to defending herself and her feeble attempts at attack were blocked or evaded effortlessly by the quick-thinking Haryana girl. In the end, it was hardly a surprise that judges ruled unanimously in Sonia's favour.
M C Mary Kom struck gold in the women's competition but India's men were denied a complete sweep by traditional powerhouses Cuba and Uzbekistan on an exciting final day of the India Open boxing tournament, in Delhi, on Thursday.
Indian pugilist Sonia Lather was assured of a medal in the 57kgs at the AIBA World Women's Boxing Championship, only the colour had to be decided on Friday in a thrilling final in Astana, Kazakhstan.
The event, in Astana, Kazakhstan, is the final qualifying tournament for women boxers in the 51kg, 60kg and 75kg Olympic categories and has 12 Rio tickets on offer. Which means pugilists will have to at least make the semi-finals in the three chosen divisions to book a berth.
Celebrated boxer M C Mary Kom will aim for a historic sixth gold at the AIBA Women' World Championships, the build up of which has been marred by a row over lone Kosovan boxer's participation and poor quality air in the national capital.
M C Mary Kom (51kg) and Shiva Thapa (60kg) were among the prominent names assured of medals as the host nation continued to dominate the ring in the US $100,000 India Open boxing tournament for men and women, in Delhi, on Tuesday.
A summary of sports events and sports persons, who made news on Friday
Summary of sports events and persons who made news on Thursday.
Nikhat from Telengana was handed the fourth spot in the 51 kg category which already has the six-time World Champion MC Mary Kom, RSPB's Jyoti Gulia and Haryana's Ritu Grewal as other contenders.
A summary of sports events and persons who made news on Thursday
A summary of sports events and sports persons, who made news on Sunday
A summary of sports events and persons who made news on Monday
A summary of sports events and persons who made news on Saturday
A summary of sports events and sports persons, who made news on Saturday.