Manchester City moved back into third place and almost guaranteed Champions League qualification thanks to a 3-1 home victory against West Bromwich Albion on Tuesday at the Etihad Stadium.
Arsenal beat Brighton and Hove Albion 3-2 to reach the FA Cup fifth round.
Philippe Coutinho inspired Liverpool to a comfortable 3-1 home win over Everton in the 228th Merseyside derby on Saturday to move provisionally up to third in the Premier League.
Monaco owe most of their recent success to their young guns, but when they face Manchester City looking to overturn a two-goal deficit in their Champions League last-16 tie on Wednesday, they will turn to a more experienced player in Radamel Falcao.
Atletico Madrid demonstrated their remarkable team spirit to come roaring back from two goals and a man down to draw 2-2 at Liga debutants Girona on Saturday, after Antoine Griezmann had been sent off for the first time in his career.
Brief reports of English Premier League matches on Saturday:
Key moments in Chelsea's Premier League title-winning season.
This and more from the happenings in the world of football
Leicester go five clear after win at Everton
Leaders Chelsea stretched their Premier League winning run to a club record-equalling 11 as Diego Costa's header shortly before halftime secured a 1-0 victory at London rivals Crystal Palace on Saturday.
English clubs took their spending on players for the season soaring past 1 billion pounds on Monday, but the biggest signing on transfer deadline day was that of a manager as Manchester City confirmed Pep Guardiola will take over this summer.
The club versus country row which has dogged England in the past reared its ugly head once again with manager Roy Hodgson saying he should not be solely responsible for resting 'tired' Liverpool forward Raheem Sterling.
This and more from the happenings in the world of football
News of all that's transpired on and off the football field
Second-half goals from Willian and Diego Costa helped Chelsea ease past Hull City 2-0 on Saturday and grab their first win in four Premier League games.
Santi Cazorla scored a 94th-minute penalty as sub-par Arsenal beat Southampton on Saturday with Laurent Koscielny's overhead kick having earlier cancelled out Petr Cech's own goal.
Images from the English Premier League matches played at Old Trafford on Saturday
Antonio Conte brushed aside the praise being heaped upon him and his high-flying Chelsea team on Friday, adamant that he would not let the plaudits distract them in their surge towards the English Premier League title.
Andy Carroll scored a eight-minute hat-trick as West Ham United's last London derby at Upton Park ended in a barnstorming 3-3 draw with Arsenal on Saturday -- a result that dented both club's respective ambitions.
City are 18 points clear of second-placed Liverpool after beating Chelsea 1-0 at the Etihad Stadium on Sunday and need just four wins from their final nine games to be sure of the title.
Following Angel Di Maria's nightmare stint, Bikash Mohapatra/Rediff.com says the 'Theatre of Dreams' has never been a happy a hunting ground for players from the continent
A summary of sports events and sports persons, who made news on Tuesday
Photos from the Champions League matches played across Europe on Tuesday