Juventus's Serie A unbeaten run came to an end after 49 matches on Saturday when Diego Milito's double helped Inter Milan win 3-1 in a pulsating 'Derby of Italy' clash in Turin.
From heroes to zeros and back again, Leicester City's remarkable rollercoaster ride took another twist as a superb 2-0 victory over Sevilla put them in the quarter-finals of the Champions League on Tuesday.
Manchester City have one just victory from their last 10 games across all competitions.
Juventus hit the woodwork three times and had a goal controversially disallowed as they were held 0-0 at Genoa on Sunday, their sixth draw in seven Serie A games leaving them further behind leaders AC Milan.
An Italian court has sentenced former Juventus general manager Luciano Moggi to five years and four months in jail for his role in the 2006 match-fixing case which led to Juve being demoted and having their 2005 and 2006 Serie A titles taken away.
Pressure is mounting on coach Claudio Ranieri as his stumbling Juventus side host nine-times European champions Real Madrid in Turin in the standout clash of Tuesday's Champions League ties.
Juventus regained the Serie A lead after Alessandro Del Piero scored a late free kick on his 700th appearance for the club to seal a 2-1 home win over Lazio on Wednesday.
News of all that's transpired on and off the football field
Gennaro Gattuso finally had fans talking about his talent rather than his temper after his rare goal gave AC Milan a 1-0 win at beleaguered Juventus and stretched their Serie A lead to eight points on Saturday.
Juventus missed the chance to join Inter Milan at the top of Serie A after losing 3-1 at promoted Napoli following two dubious penalties on Saturday.
Croatian forward Ante Budimir scored twice to help Osasuna earn a shock 4-2 home win over leaders Barcelona.
A first-half penalty earned Lille a shock 1-0 home victory over holders Real Madrid in the Champions League group phase on Wednesday.
A 2-2 draw to Perugia was enough to secure their 27th title.
Napoli kept in touch with Serie A leaders Juventus with a 5-1 thumping of bottom club Pescara on Sunday while Inter Milan scraped a 1-0 win over Palermo.
Napoli revived their hopes of claming Serie A's final Champions League qualifying slot and dented Juventus's when they heaped more misery on the Turin side with a 3-1 comeback win on Thursday.
IMAGES from the UEFA Champions League matches played on Wednesday
Valencia turned the tables on a stunned Basel side to reach the Europa League semi-finals on Thursday with a 5-0 win after extra time thanks to a Paco Alcacer hat-trick as they recovered from a three-goal first-leg deficit.
Juventus will ask Italy's soccer authorities to strip the 2006 Serie A title from Inter Milan after developments in a criminal trial into match-fixing, the Turin club said on Monday.
Second-half goals from Stephan Lichtsteiner and Emanuele Giaccherini sent Juventus four points clear in Serie A after they defeated Atalanta 2-0 in Bergamo on Saturday to finish the first half of the season unbeaten.
Bayer Leverkusen crushed hosts VfL Bochum 5-0 to stretch their remarkable unbeaten run across all competitions this season to 50 consecutive matches.
Serie A leaders Juventus scored twice in the last five minutes to win 3-2 at Inter Milan, who had earlier come from behind to lead despite playing with 10 men in an extraordinary match on Saturday.
Juventus slumped to another surprise defeat on Wednesday when the champions lost 1-0 at Sassuolo while AS Roma reclaimed top spot in Serie A with a 3-1 home victory over Udinese.
Barcelona must to wait to confirm a place in the Champions League last 16 after dropping points for the first time in Group D in an absorbing 0-0 draw at Olympiakos Piraeus on Tuesday.
Images from the UEFA Champions League quarter-final first leg matches played on Wednesday
Lionel Messi was at the top of his game as Barcelona earned a 3-2 win at Athletic Bilbao on Wednesday to move up to third in La Liga.
Juventus will be hoping to make it 11 victories out of 11 against French teams in knockout ties when they face AS Monaco in the second leg of their Champions League quarter-final on Wednesday.
Juventus added a touch of controversy to their Serie A title celebrations on Saturday by suggesting it was the 33rd, not the 31st, time they had won the league.
Juventus have been deducted 15 points for the current season by an Italian soccer court investigating its transfer dealings.
Juventus' wretched start to the season continued when they needed a late penalty to avoid defeat as the Serie A champions were held to a 1-1 home draw by early leaders Chievo Verona on Saturday.
An insatiable Lionel Messi scored for the eighth game in a row in all competitions as La Liga champions Barcelona saw off a gutsy Girona side 2-0 to go five points clear at the top of the standings.
Unbeaten Juventus snatched a late goal to draw 1-1 at AC Milan in Serie A's top of the table clash on Saturday after the hosts had a goal disallowed when officials failed to spot the ball had crossed the line.
Barcelona have been linked to a host of forwards during the winter transfer window as they seek experienced backup options for Luis Suarez.
After losing only three league games last season Juventus have now lost the first two of the new campaign as a deserved 2-1 defeat at AS Roma on Sunday condemned the champions to their worst-ever Serie A start.
Arturo Vidal's double helped Juventus to their 12th straight league win with a 4-2 triumph over Sampdoria and saw the Italian champions restore an eight-point lead at the top of Serie A.
News of all that's transpired on and off the football field.
IMAGES from the UEFA Champions League matches played on Tuesday
A round-up of the top-flight football matches played across Italy and Germany on Sunday
News of all that's transpired on and off the football field