The 33-year-old said that he has not had enough time to practise sufficiently due to inflammation in his left wrist.
'I'm happy to have the chance to try to stop, one more time, somebody from making history.'
Since 2003, one of Roger Federer, Novak Djokovic, Rafael Nadal or Andy Murray have won the title at Wimbledon, with the Swiss leading the way with eight titles.
Rafael Nadal may have won the French Open a record 12 times but the Spaniard feels this year's conditions will be the most difficult he has ever faced at Roland Garros and mean he must be at his best to have a chance of retaining his title again.
Rafael Nadal set up an Italian Open semi-final with Stefanos Tsitsipas on Friday thanks to a 6-4, 6-0 win over Fernando Verdasco.
'...What is at stake, however, is his ability to assess the need for vaccinations or whether the vaccine has been tested for a sufficient period of time. And ... he has neither the knowledge nor the studies nor the research work that would allow him to form an opinion about it.'
Rafael Nadal's hopes of winning the year-ending ATP Finals for the first time live on after the Spaniard beat defending champion Stefanos Tsitsipas 6-4, 4-6, 6-2 on Thursday.
'I played a good match, maybe he was a little bit tired from New York (where) he played an amazing tournament.'
Red-hot Rafael Nadal faces Delbonis, says majors tally not a focus
Brandon Fernandes returned to the side as Goa coach Juan Ferrando named three changes to the line-up that lost against ATK Mohun Bagan with Aiban Dohling and Jeorge Ortiz being the other two.
'During the grass court season, I unfortunately experienced a setback with my knee, and have accepted that I must withdraw from the Tokyo Olympic Games.'
A summary of Friday's action at the US Open.
Summary of sports events and persons who made news on Monday.
Rafael Nadal gets the opportunity to avenge his only defeat in 10 meetings with Diego Schwartzman, which he suffered a little over two weeks ago, when Spain's 12-time French Open winner faces the Argentine in the semi-finals at Roland Garros on Friday.
Rafael Nadal is tied with Roger Federer as the player with the most men's singles majors and the Spaniard can now overtake his great rival who has skipped the Australian Open.
A round-up of Wednesday's action in the UEFA Champions League.
Novak Djokovic had hoped to have the crowd behind him as he began his bid to win the US Open and complete the calendar-year Grand Slam, but the Serb said the atmosphere was "not ideal" as Flushing Meadows fans roared on his underdog opponent.
No Italian man has won a Grand Slam since Adriano Panatta triumphed at Roland Garros in 1976 and if there is any chance that Sinner, Musetti or Berrettini will lift the Musketeers Cup this year, they will face their biggest obstacles in the next round when they take on the might of Nadal, Djokovic and Federer respectively.
Halep said she would not recover from a calf injury in time, Wawrinka underwent foot surgery that would rule him out of the Games
It was Novak Djokovic's first match this year after his Australian Open hopes were dashed when he was deported following an 11-day saga revolving around his decision not to have a COVID-19 vaccination.
Ashleigh Barty lifted the season-ending WTA Finals trophy and led Australia to their first Fed Cup final since 1993, while Nadal won his 4th ITF Award for winning two Slams this season.
A round-up of Tuesday's action in the UEFA Champions League.
Earlier, Ukraine took a 2-0 lead over Japan as world number five Elina Svitolina took the first point of the Billie Jean King Cup era.
Defending champion Novak Djokovic and Rafael Nadal will clash for the Italian Open title after the top two seeds advanced to the final of the Masters tournament on Saturday.
Tennis Australia (TA) planned for players and their entourages to arrive in Victoria in mid-December to have time to undertake a mandatory two-week quarantine period before competing in January.
A round-up of Wednesday's action in the UEFA Champions League.
While taking questions about his first round victory, the World No 2 spotted a journalist snoozing away in the corner of the room.
A three-day hearing of the Court of Arbitration for Sport (CAS), held over video-conference, concluded on Wednesday and the Lausanne-based court said they would now begin deliberations.
The 21-year-old German became only the fifth active player to win at least three Masters 1000 titles -- joining the 'big four' of Rafael Nadal, Roger Federer, Novak Djokovic and Andy Murray.
Images from the Wimbledon semi-final played between Roger Federer and Rafael Nadal on Friday
IMAGES from the Australian Open matches played on Wednesday.
Luis Suarez has agreed a deal with the club to end his contract and settled on personal terms with Atletico Madrid,
Images from Monday's action at the Australian Open.
Twelfth seed Djokovic resumed two sets to one ahead after snatching a third-set tiebreak the previous night before Wimbledon's 11pm curfew left the match on a knife edge.
Djokovic remained unflustered despite dropping the opening set and suffering several tumbles on the greasy surface.
Medvedev whips Dimitrov to enter US Open final
Seven months after the last French Open ended the tournament is back, boosted by the prospect of more spectators despite ongoing COVID-19 restrictions and forecasts of good weather.
Thousands of mask-free spectators flocked into the stadium
Images from Day 3 of the French Open matches played at Roland Garros on Tuesday
Team Europe's Nadal was scheduled to take on Team World's Nick Kyrgios in his singles clash before partnering Swiss Federer to face John Isner and Jack Sock.