Roger Federer avoided any more security scares as he moved smoothly into the third round of the French Open on Wednesday but danger still lurks in the bottom half of the draw, namely in the shape of Japan's Kei Nishikori.
But for the 23-year-old Bouchard, a former world number five who has slumped to 56th in the rankings, it was another blow after her first-round exit in Indian Wells.
Top seed Andy Murray could meet Roger Federer or Kei Nishikori in the third round, while Serena faces tricky Belinda Bencic in opening round
Images from Day 1 of the Australian Open, in Melbourne, on Monday.
An ailing Rafael Nadal added his name to the list of upsets at the Shanghai Masters after the Spaniard suffered a 6-3, 7-6(6) loss to Feliciano Lopez in Wednesday's second round, as fourth seed Stanislas Wawrinka and in-form Kei Nishikori also made early exits. Nadal's great rival Roger Federer survived a huge scare, saving five match-points before overcoming Argentina's Leonardo Mayer 7-5, 3-6, 7-6(7).
Venus Williams staged a spirited comeback to down third seed Petra Kvitova 4-6, 7-5, 6-4 and reach the third round of the BNP Paribas Open in Indian Wells on Saturday.
Photos from the Australian Open matches played at Melbourne Park on Wednesday.
India ended its campaign at the Fed Cup with a fourth place finish after losing the classification tie 1-2 to Korea as the team badly missed injured Karman Kaur Thandi, who did not play on Saturday, in Astana, Kazakhstan.
Rafael Nadal's announcement on Friday that he will miss the ATP World Tour Finals because of appendicitis ended a difficult year for the Spaniard during which he has endured injury, illness and worrying defeats.
Wozniacki battles past Kerber into Eastbourne final
Former world number one Novak Djokovic suffered a surprise second-round exit at the Barcelona Open when the Serb was beaten 6-2, 1-6, 6-3 by world number 140 Martin Klizan on Wednesday.
Milos Raonic overcame third seed Grigor Dimitrov 7-5, 3-6, 6-3 to reach the third round at the Madrid Open on Tuesday and set up an all-Canadian clash with teenager Denis Shapovalov.
Thursday's match was just Venus Williams's seventh of the year and first since January's Australian Open, where she fell to Simona Halep in the round of 32.
Third seed Rafael Nadal battled through mid-match cramps for more than an hour before he lurched into the third round of the Australian Open with a 6-2, 3-6, 6-7(2), 6-3, 7-5 victory over American qualifier Tim Smyzcek.
Roger Federer boasted of his fitness, Maria Sharapova felt a bit rusty and Andy Murray berated himself but all three eased into the second week of the Australian Open with third round victories at Melbourne Park on Saturday.
Images from Day 5 of the French Open in Paris on Thursday.
It was a day of surprises at Flushing Meadows in New York as seeded players were knocked out one after the other on Friday.
Summary of sports events and persons who made news on Saturday
The returning Scot also announced his withdrawal from next week's Rogers Cup in Toronto.
World No 1 Novak Djokovic maintained his perfect tournament record and advanced to his fifth China Open final with a 6-3, 6-4 victory against Andy Murray on Saturday.
PHOTOS from day four of the Wimbledon championships at the All England Lawn Tennis and Croquet Club in London on Thursday.