Chelsea's Marcos Alonso and Real Madrid's Nacho were notable absentees in defence, along with Atletico Madrid midfielder Koke.
Lionel Messi, Luis Suarez and Neymar combined to devastating effect as Barcelona swatted Celtic aside 7-0 at the Nou Camp to lay down a marker in Champions League Group C on Tuesday.
Now, Real Madrid have never won the Spanish treble and are fighting tooth and nail in La Liga to prevent arch-rivals Barcelona scooping Champions League and domestic league and Cup titles for a second time.
Images from the World Cup qualifying matches played on Wednesday night.
Spain began a new era under Luis Enrique in impressive fashion as they came from a goal down to outplay England in a 2-1 win in their Nations League opener at Wembley Stadium on Saturday.
In leading Real Madrid to their 11th European Cup less than five months after inheriting an unhappy team from Rafael Benitez, Zinedine Zidane has cemented his heroic status at the Bernabeu and appears to have assured his immediate future.
Just as he did two years ago, Sergio Ramos left his footprint all over Real Madrid's Champions League final triumph over Atletico Madrid following a turbulent 12 months.
Barcelona came through a testing local derby at Espanyol, winning 3-0 to cling to their slender lead at the top of La Liga after rivals Real Madrid had set the challenge by beating Valencia 2-1 in the earlier kick-off.
Suarez moved ahead of Ronaldo as the league's top scorer on 34 goals after netting four times, twice with penalties, in the space of 25 second-half minutes
Real Madrid beat Leganes 4-2 on Wednesday despite resting key players including Cristiano Ronaldo and Gareth Bale as goals from Alvaro Morata and James Rodriguez helped them stay top of La Liga after Barcelona cruised to a 3-0 win over Sevilla.
Holders Barcelona crashed out of the Champions League after being stifled by a brilliantly well-organised Atletico Madrid.
Barcelona followed up Saturday's win over Real Madrid with another victory when Alexis Sanchez set the champions on their way to a 3-0 success at Celta Vigo on Tuesday that put them four points clear at the top of La Liga.
Barcelona's Lionel Messi broke free from Arsenal's shackles to score two late goals and put the Champions League holders on the brink of the quarter-finals with a clinical 2-0 victory at the Emirates Stadium on Tuesday.
Paris St Germain are sweating over striker Zlatan Ibrahimovic's fitness as the French champions look fragile ahead of Barcelona's visit in Champions League Group F on Tuesday.
The South American trio of Lionel Messi, Neymar and Luis Suarez reached a scorching 108 goals for the season following the La Liga leaders' 8-0 destruction of Cordoba on Saturday but the team's defence is yet to dispel doubts
Lionel Messi produced a vintage second-half performance to help Barcelona to a 4-1 win over local rivals Espanyol on Sunday which saw the champions cut the gap on La Liga leaders Real Madrid to three points.
Uruguay's Luis Suarez has been suspended for nine matches and banned for four months from any football-related activity for biting an opponent, during the World Cup match against Italy.
Real's Cristiano Ronaldo will be going in search of his third consecutive World Player of the Year award
Images from the FIFA World Cup qualifying matches on Sunday night.
Barcelona dropped their first points of the La Liga season as their star-studded forward line misfired in a 0-0 draw away to Malaga on Wednesday.
Tuesday's match was the latest masterclass from the South American trio, known in Spain as 'MSN', whose goals have put Barca on the brink of repeating 2009's treble of Champions League and Spanish league and Cup triumphs, the only time a La Liga club have achieved the feat.
We once again present a special feature on the ten worst earthquakes that had shaken the world and caused immense damage in the past 25 years.
Bayern Munich will not only have to overturn a 3-0 Champions League semi-final first leg deficit against Barcelona on Tuesday but they will have to do it against a superb defence and in the midst of their biggest slump in years.
Barcelona's preparations for next season were thrown off course on Friday when the Spanish champions unexpectedly announced coach Tito Vilanova was stepping down due to ill health.
Lionel Messi broke a Spanish hat-trick record and Luis Suarez struck twice as a rampant Barcelona took over top spot in La Liga with a 6-1 hammering of Rayo Vallecano on Sunday.
Fernando Torres stole the show with a dramatic double as Atletico Madrid secured a battling 2-2 draw at Real Madrid on Thursday that dumped the holders out of the King's Cup 4-2 on aggregate.
Messi stretched Barca's lead by finishing off a brilliant move with Luis Suarez in the 50th minute and the Uruguayan joined his close friend and strike partner on 15 league goals by robbing an Eibar defender and finishing inside the near post in the 68th.
Holders Barcelona produced a second-half blitz to come from behind and beat Athletic Bilbao 3-1 to book a place in the King's Cup semi-finals after Atletico Madrid crashed out in a shock 3-2 defeat by Celta Vigo.
Biting opponents may be appalling but it is harmless and should not be punished as severely as a bad tackle, says controversial Barcelona striker Luis Suarez.
Barcelona need to avoid getting sucked into the Spanish obsession with El Clasico when they face Ajax Amsterdam in the Champions League on Tuesday.
Lionel Messi will have another chance to match or surpass Telmo Zarra's six-decade-old La Liga scoring record of 251 goals when Barcelona host promoted Eibar on Saturday.
The Portuguese admitted he had over-stretched himself after having knee problems at the back end of the last season which he carried into the World Cup and then suffered a hamstring injury at the start of this campaign.
Images from the Nations League matches.
Lionel Messi scored one penalty and missed another as his double helped Barcelona sweep Levante aside in the second half in a 4-1 victory on Sunday to maintain their perfect La Liga start.
Gijon spoiled Asier Illarramendi's return to Real Sociedad's midfield after rejoining from Real Madrid this week when they held the Basque club, coached by Scot David Moyes, to a 0-0 draw in San Sebastian.
If you ask Barcelona and Spain fans about their most cherished footballing memories over the past decade the chances are they will involve an exquisite intervention from midfield maestro Xavi.
News of all that's transpired on and off the football field
A red hot Luis Suarez scored four goals and contributed three assists as Barcelona's stuttering La Liga title charge sparked back to life with a spectacular 8-0 thrashing of Deportivo La Coruna on Wednesday.
Cristiano Ronaldo struck twice as leaders Real Madrid subdued Eibar 4-0 on Saturday while Lionel Messi set a La Liga record of 253 goals with a hat-trick in second-placed Barcelona's 5-1 rout of Sevilla.
Luis Suarez is likely to play his first competitive game for Barcelona in La Liga's "Clasico" against Real Madrid later this month and he says it is no coincidence his four-month biting ban expires the day before one of biggest fixtures in world soccer.