The world No 1 is certainly buoyed by the prospect of emulating his achievement of holding all four majors but knows that nothing less than perfection will be required.
World No 4 Del Potro is still sidelined with a right knee injury sustained in Shanghai last month.
Roger Federer survived a stern test from Spain's Roberto Bautista Agut to reach the Miami Open quarter-finals on Tuesday, while top-seeded Swiss compatriot Stanislas Wawrinka was eliminated on his birthday.
But for the 23-year-old Bouchard, a former world number five who has slumped to 56th in the rankings, it was another blow after her first-round exit in Indian Wells.
Tournament officials said there was no heat rule in effect on Friday for the first time in three days, with cloud cover expected to bring cooler temperatures.
Indian tennis ace Rohan Bopanna and his Romanian partner Florin Mergea knocked out of the Monte Carlo Masters after suffering straight-sets defeat in the quarter-final clash of the men's doubles event on Friday.
The Tokyo 2020 Olympics torch lighting ceremony in ancient Olympia will be the first in more 35 years to be held without spectators after organisers introduced tighter measures to protect against the coronavirus. Here is a list of international sports events hit by the coronavirus outbreak.
A six-time champion at Flushing Meadows, Williams was once money in the bank when it came to the US Open
Ana Ivanovic of Serbia celebrates defeating Caroline Wozniacki of Denmark during their match at the Indian Wells WTA tennis tournament in Indian Wells, California.
The French Open is the only Grand Slam title to have eluded Novak Djokovic and the steely-eyed Serb has adopted a philosophy of reverse psychology in a bid to claim the coveted crown.
Bianca Andreescu, 19, the first Canadian to win a major in the professional era, prevented Serena Williams from equalling Margaret Court's record of 24 Grand Slam singles titles.
Roger Federer is no longer chasing the top ranking and would rather be a contender at Grand Slams than battling Novak Djokovic and Rafa Nadal to be world number one, the Swiss tennis great said.
Azarenka punished her Russian opponent's weak serve to wrap up the final in 80 minutes in relentless humidity under a searing sun in the early afternoon encounter on the Key Biscayne hardcourt.
The first meeting between Nick Kyrgios and Stefanos Tsitsipas lived up to the hype on Saturday as the Australian saved a match point in a wildly entertaining 6-4, 3-6, 7-6(7) win to reach the Citi Open final.
Former world number one Serena Williams will not be seeded at this year's French Open, according to the organisers of the May 27-June 10 claycourt Grand Slam.
Former world number two Tommy Haas officially announced his retirement from tennis at the BNP Paribas Open in Indian Wells on Thursday, ending a career that spanned more than two decades.
The 23-times Grand Slam champion looked a completely different player from the person who smashed her way into the semi-finals of the doubles with Caroline Wozniacki on Wednesday but managed to do just enough to beat the 86th-ranked McHale.
Serbia's Novak Djokovic, who beat Switzerland's Roger Federer to win his 16th Grand Slam title on Sunday:
The news comes after Sharapova, who said the decision to end their four-year partnership was "mutually agreed", was beaten by 44th-ranked Naomi Osaka in the first round of the BNP Paribas Open in California on Wednesday.
Serena Williams' return to the WTA Tour following the birth of her first child will be the 'greatest challenge' of her career
Nick Kyrgios is confident he can overcome his injury woes and win his first Wimbledon title next week, the 22-year-old Australian said after winning an exhibition match at the Boodles tournament on Thursday.
Novak Djokovic sat out last year's U.S. Open to rest an elbow injury that eventually required surgery, but that pain and frustration felt like a distant memory on Friday when the Serb completed his march to the New York final with authority.
On a day when top seed Sloane Stephens survived a scare before beating Ajla Tomljanovic 4-6, 6-4, 6-4, Sakkari showcased supreme court coverage skills throughout her almost two-hour match against Bertens.
'Everyone thinks it was a money-related issue, but it wasn't'
It was a triumphant return to the tour for Djokovic
Novak Djokovic has apologised for his comments suggesting tennis's top men should get paid more than women after he drew criticism from current and former players.
Top seed Rafa Nadal overwhelmed Russia's Daniil Medvedev 6-3, 6-0 to win his fifth Rogers Cup on Sunday in Montreal -- the first time he has retained a title outside of clay.
IMAGES from the matches played at the Miami Masters on Sunday
Raonic advances, Sock ousted in Rogers Cup
Following is a list of the previous matches between Switzerland's Roger Federer and Spain's Rafael Nadal ahead of their meeting in the title decider at the Australian Open on Sunday
Coach Patrick Mouratoglou claimed Serena Williams' fitness had since gone up a notch and Margaret Court's all-time record of 24 Grand Slam singles titles may well be in peril at the Australian Open.
Jelena Jankovic eased into the last four at the BNP Paribas Open on Thursday when Ukrainian qualifier Lesia Tsurenko retired from their quarter-final with an ankle injury while trailing 6-1, 4-1.
Maria Sharapova rose to No. 2 in the rankings on Monday after her impressive title run at the BNP Paribas Open but says she is motivated much more by Grand Slam glory than the prospect of regaining the top spot.
Eighteen time Grand Slam champion Roger Federer has climbed up to the fourth spot in the latest ATP rankings after lifting his third Miami Open title by beating long-time rival Rafael Nadal.
Simply being back on the tennis court felt like a victory for Mardy Fish, on Sunday, after the American returned to action following a lengthy recovery from a heart condition.
Indian tennis ace Sania Mirza and her Swiss doubles partner, Martina Hingis, have booked their place in the semi-finals of the Italian Open after securing a straight sets win in the women's doubles event in Rome on Friday.
Defending champions Sania Mirza and Martina Hingis suffered yet another early exit on the American hardcourts as the world number one women's doubles pair crashed out of the Miami Open in the second round on Tuesday.
Switzerland's Martina Hingis and Taiwan's Chan Yung-Jan won the US Open women's doubles title on Sunday
Naomi Osaka announced her arrival on the big stage at the US Open on Thursday, beating last year's runner-up Madison Keys 6-2, 6-4 to reach her first Grand Slam final.
A look at the records of Spain's Rafael Nadal and Serbia's Novak Djokovic before their title clash at the Australian Open on Sunday (prefix number denotes seeding):