Samuel Eto'o scored twice to give ambitious Anzhi Makhachkala a 2-0 Europa League win over Young Boys on Thursday while Liverpool lost 3-2 at home to Udinese and Videton, Sparta Prague and Molde pulled off surprise wins.
Parma, joint bottom of Serie A alongside Cesena, have signed Uruguay midfielder Cristian Rodriguez and Portugal forward Silvestre Varela, both on loan, the club said on Tuesday.
European champions Manchester United were held to a 2-2 draw by Porto at Old Trafford to leave their Champions League quarter-final on a knife-edge ahead of the second leg in Portugal next week.
Uruguay's Cristian Rodriguez scored a soft goal in the holders' laboured 1-0 win over outsiders Jamaica when they opened their defence of their Copa America title on Saturday.
Financially-stricken Parma have been hit with a further two-point penalty for failing to pay players' salaries the Italian Football Federation (FIGC) have announced.
Chile beat Ecuador 2-1 in their closing South American qualifier in Santiago on Tuesday as both went through automatically to the 2014 World Cup finals in Brazil.
Luis Suarez scored an equaliser and was just wide with what could have been a spectacular winner as Uruguay were held to a 3-3 draw by Costa Rica in a friendly.
Carlos Tevez scored twice for Boca Juniors on Saturday but the main talking point from their 3-1 win over Argentinos Juniors in a stormy Argentine league game was his studs-up challenge that left defender Ezequiel Ham with a broken ankle.
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Uruguay are all but assured of a place at the 2014 World Cup finals after Edinson Cavani led the twice champions to a 5-0 away rout of Jordan in the first leg of their qualifying playoff on Wednesday.
It is testament to Steven Gerrard's ability that his Liverpool career will be remembered for heroic acts of willpower that ensured no deficit was irretrievable and no opponent unbeatable, rather than the league title that eluded him.
Portugal captain Cristiano Ronaldo struck his fifth international hat-trick, including a spectacular volleyed opener, to lead the European champions to a 5-1 win over the Faroe Islands in their World Cup qualifier on Thursday.
Switzerland struck twice in quick succession to stun Euro 2016 champions Portugal 2-0 in a World Cup qualifier on Tuesday and hand them a first competitive defeat in two years under coach Fernando Santos.