Sen, who had broken the three-year jinx of first-round exits in the tournament when he defeated Singapore's Jia Heng Jason Teh on Wednesday, succumbed in the pre-quarterfinals against Hong Kong-China's Lee Cheuk Yiu 22-22, 15-21 in 53 minutes.
Ashwini and Tanisha, who won the Guwahati Masters super 100 title, last month will take on Malaysia's Pei Kee Go and Mei Xing Teoh next.
Tanisha Crasto and Dhruv Kapila outclassed Adnan Maulana and Indah Cahya Sari Jamil in straight games in the first round match.
Satwik-Chirag had lost each of the two semifinals in straight sets and their aim would be to go the distance in the upcoming tournament.
The 30-minute duel had some exciting moments as the two players fought hard for supremacy with Sindhu conceding a 4-2 lead to Zhang, who could only manage a one-point advantage at the break.
Double Olympic medallist PV Sindhu, Commonwealth Games gold medallist Lakshya Sen, Tokyo Olympic B Sai Praneeth and Ruthvika Shivani Gadde will be in action later on Wednesdat.
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