Another win would confirm that Barca are heading in the right direction after pushing the reset button following the loss of Lionel Messi in the close season due to their financial problems.
Paris St Germain had a chance to extend their Ligue 1 lead to five points after RC Lens drew 1-1 at Troyes and Olympique de Marseille and Monaco shared the spoils on Saturday.
The local government, meanwhile, is deploying more than 200 national police officers to prevent crowds assembling, with mayor Jose Luis Martinez-Almeida also asking people to stay away.
Real Madrid saw off a stirring Chelsea fightback to book their place in the Champions League semi-finals following a 3-2 defeat after extra time in a scintillating second leg at the Santiago Bernabeu on Tuesday to go through 5-4 on aggregate.
Ancelotti replaces Zinedine Zidane, who left Real last month.
Real Madrid president Florentino Perez has tested positive for COVID-19, the Spanish champions said on Tuesday.
A round-up of Saturday's action in La Liga and the Bundesliga.
Tottenham Hotspur forward Gareth Bale is relishing the opportunity to work with manager Jose Mourinho who had unsuccessfully tried to sign the Welshman in the past.
The Welsh captain was called a "parasite" and accused of faking a back injury that kept him out of Real Madrid's humiliating loss to Barcelona
Real are on 81 points with four games to go. They are 17 points ahead of nearest rivals Sevilla.
The old format was skewed in favour of the bigger clubs, who could rest players for a first leg and swallow defeat before calling on their stars to turn the tie around in the return game.
A dominant yet wasteful Real ravaged their rivals in the first half while spurning a string of clear chances at the Santiago Bernabeu.
Lionel Messi received a surprise house-share offer from Real Madrid captain Sergio Ramos
Union Berlin's Paul Jaeckel scored a 76th-minute winner to give his team a 1-0 victory at VfB Stuttgart on Sunday and send them two points clear at the top of the Bundesliga.
Real Madrid supporters urged Cristiano Ronaldo to stay at the club during celebrations at the Santiago Bernabeu stadium on Sunday to mark their third consecutive Champions League title after an open-top bus parade through the Spanish capital.
Zinedine Zidane has said his side are in a delicate situation as they prepare to host arch-rivals Barcelona in a La Liga title showdown on Sunday
With no fans allowed into venues and Real playing their home games at the 6,000-capacity Alfredo Di Stefano stadium while the Santiago Bernabeu is being refurbished, it will be a title race unlike any other.
Constantine interviewed by Chennaiyin FC
Atletico Madrid earned a 1-1 draw away to Girona in a chaotic and entertaining Copa del Rey last 16 first-leg match on Wednesday, leaving the tie finely balanced.
A round-up of Wednesday's action in the UEFA Champions League.
Jeswin Aldrin, who had already qualified for the championships, however missed the cut.
Ronaldo leads the scoring charts in the Champions League for the sixth season running with nine goals and is the top marksman in the competition's history with 114 strikes, 17 more than nearest challenger Lionel Messi.
Pierre-Emerick Aubameyang scored twice as a rejuvenated Barcelona gave a football masterclass to inflict a humiliating 4-0 defeat on rivals Real Madrid on Sunday.
Madrid were not at their best but moved three points clear of rivals Barcelona.
Tennis stars Novak Djokovic and Rafael Nadal were spotted together as Real Madrid reached their 14th Champions League final.
After a string of middling transfer windows, Manchester United have made their biggest statement of intent in recent years by signing centre back Raphael Varane and winger Jadon Sancho.
The Welshman has a contract until 2022 and was set to make a lucrative move to the Chinese Super League last year before the transfer was scuttled when Real made a last-minute decision to insist on a transfer fee rather than terminate his contract.
Karim Benzema and Vinicius Jr both scored a brace to give the LaLiga leaders a 4-1 home win over Valencia
Cristiano Ronaldo continued his rich vein of form by scoring twice in Real Madrid's 2-1 home win over struggling Sporting Gijon on Saturday, although the La Liga leaders got a lucky break when the visitors squandered a second-half penalty.
A round-up of Wednesday's action in the UEFA Champions League.
IMAGES from the La Liga matches played on Sunday
Barcelona were hailed as La Liga champions-elect in the Catalan media after their 1-0 win at Real Madrid on Saturday, while the capital's press called for sweeping changes at Real after another domestic failure.
The three Premier League and three La Liga clubs in the last eight avoided each other, with Manchester City up against Atletico Madrid and Liverpool to face Portuguese side Benfica.
A round-up of Wednesday's action in the UEFA Champions League.
Following public comments from La Liga chief Javier Tebas, who said it was "not ideal" for the second El Clasico meeting between Real and Barca last season to be played with the latter having already won the league title, the two sides will face off earlier this campaign.
Zinedine Zidane has stepped down as Real Madrid coach with immediate effect five days after his team were pipped to the La Liga title by city rivals Atletico Madrid, the Spanish club said on Thursday.
The Bernabeu faithful have never taken Gareth Bale to their hearts with injury problems and a perceived lack of integration into the side often used as sticks to beat him with.
Real Madrid showed their character by beating Barcelona 2-0 in Sunday's top-of-the-table 'Clasico', leapfrogging their rivals at the La Liga summit after a week in which their pride had taken a beating at home and in Europe. Brazilian teenager Vinicius Jr scored the opener in the 71st minute with a strike that deflected off Gerard Pique, flummoxing goalkeeper Marc-Andre ter Stegen who had made some jaw-dropping saves, and substitute Mariano added the second in added time.
More than 1,000 people have died from coronavirus in the UK as of 27 March, and more than 17,000 have tested positive for the virus, according to figures from the Department of Health and Social Care.
In separate statements, the clubs announced that the matches would take place at each of their stadiums and would raise money for boosting healthcare resources in Italy and Spain, but not in Germany.