American Rajeev Ram and Briton Joe Salisbury overcame a slow start to beat Bruno Soares and Jamie Murray 3-6, 6-2, 6-2 in the US Open men's doubles final on Friday.
In the decider, Berrettini broke twice for a 4-2 lead but a rejuvenated Monfils dug deep and raced around the court to fight off three match points to force a final-set tiebreak. But it was Berrettini who leaned on his powerful serve to prevail and become the fourth Italian man to reach a Grand Slam semi-final in the Open Era.
Novak Djokovic said he was "sad and empty" after a being disqualified from the US Open on Sunday after hitting a line judge in the throat with a ball during his fourth-round match against Spain's Pablo Carreno Busta.
Steady rain hit the US Open on Monday, washing out the last match on Arthur Ashe Stadium court featuring five-time champion Roger Federer.
Images from the US Open mathches played at Flushing Meadows on Tuesday.
China's Li Na became the first player to reach the round of 16 at this year's US Open when she defeated Britain's Laura Robson 6-2, 7-5 on Friday.
Andy Murray fought off Novak Djokovic to win an epic US Open final on Monday and become the first British man in 76 years to win a Grand Slam singles title. Here are some best moments form the tournament.
Fourth-seeded Spaniard David Ferrer edged Janko Tipsarevic of Serbia 6-3, 6-7, 2-6, 6-3, 7-6 on Thursday in a see-saw slugfest marked by gutsy, gritty play to reach the semi-finals of the US Open.
Images from Day Seven of the US Open tennis tournament being played in New York.
Second seed and defending champion Novak Djokovic ousted France's Julien Benneteau in straight sets on Sunday to cruise into the US Open fourth round.
Images from the US Open matches played at Flushing Meadows on Thursday.
Britain's Andy Murray, who is forging a new reputation as a crowd favourite, will try to take his place in round three of the US Open on Wednesday.
An emotional Frances Tiafoe promised to one day hoist the US Open trophy after his Cinderella story came to a premature end on Friday with a semi-final loss to Spanish teenager Carlos Alcaraz.
Rafael Nadal boasted after his first-round US Open match that he had a video recording of being the first player to hit a ball in practice under the new roof at Arthur Ashe Stadium.
The win burnished Murray's reputation as one of the world's leading doubles exponents,
Juan Sebastian Cabal and Robert Farah became the first Colombians to win the US Open men's doubles title.
The US Open women's semi-finals scheduled for Thursday evening have been postponed due to the threat of rain.
Novak Djokovic, who won Wimbledon to take his major singles titles to 21, has opted not to be vaccinated against COVID-19. He said on Thursday he could not fly to New York for the year's final Grand Slam.
With the preliminaries now out of the way, the US Open men's competition can really begin. As expected, the world's top four players, Novak Djokovic, Rafa Nadal, Roger Federer and Andy Murray, are safely through to the semi-finals.
Andy Murray fought off Novak Djokovic to win an epic US Open final on Monday and become the first British man in 76 years to win a Grand Slam singles title.
Andy Murray of Britain won the US Open men's singles final at Flushing Meadows on Monday. The Scotsman beat Serbia's defending champion Novak Djokovic 7-6, 7-5, 2-6, 3-6, 6-2 in the final at Arthur Ashe Stadium.
Novak Djokovic and Rafa Nadal will meet in the US Open final for the second year in a row after winning their semi-finals on a day of unrelenting drama and precision tennis at Flushing Meadows on Saturday.
A summary of Saturday's action at the US Open.
Rafael Nadal and Andy Murray joined Novak Djokovic and Roger Federer in the semi-finals of the US Open on Friday to set the stage for a dramatic ending to the last Grand Slam of the year.
Roger Federer was left waiting until almost midnight to start his US Open fourth round match on Monday, but made up for the delay with a brutal 6-1, 6-2, 6-0 win over Argentine Juan Monaco to reach the quarter-finals.
Andy Murray's quest to claim his first trip to the Grand Slam winner's circle opened with an easy 7-6, 6-2 6-3 victory over India's Somdev Devvarman on Wednesday at sun-splashed Arthur Ashe Stadium.
Roger Federer showed that time was still on his side as the Swiss master rang the closing bell on Monday's opening day at the US Open tennis championship with a quick victory at Arthur Ashe Stadium.
'I understand it's a show, but under the roof we need to be a little bit more strict about the noise. All the noise stays inside, and this is difficult.'
The victory secured a first Grand Slam doubles championship for Laura Siegemund and a third for Vera Zvonareva
Naomi Osaka now gets to test her mental strength against a revitalised Victoria Azarenka, who stunned Serena Williams in Thursday's other blockbuster semi-final.
US Open Tournament Referee Soeren Friemel said there was "no other option" but to disqualify world number one Novak Djokovic on Sunday after he struck a line judge with a ball.
Andy Murray sent an ominous warning to Roger Federer and Rafael Nadal about his intentions to win the US Open when he cruised through his first match at Flushing Meadows on Wednesday after Victoria Azarenka sent a shiver through the tennis world when she fainted on court.
Naomi Osaka ended Victoria Azarenka's dream run to claim her second US Open title in three years with a 1-6, 6-3, 6-3 comeback win on Saturday which cemented her status as the sport's leading light both on and off the court.
A clash of generations will decide the US Open on Saturday with Serena Williams taking a fourth crack at Grand Slam history against teenager Bianca Andreescu, who was not even born when the American lifted her first Flushing Meadows trophy.
Images from Day 6 of the US Open in New York, on Saturday.
Some words of consolation from US Open champion Kim Clijsters made the bitter pill of a second successive Grand Slam final defeat easier to swallow for Vera Zvonareva.
Top-seeded Caroline Wozniacki chalked up her US Open semi-finals loss Friday to Russia's Vera Zvonareva as a bad day at the office - one that may have cost her the number one ranking and a million-dollar bonus.
Rafael Nadal made a smooth start to his bid to capture the one Grand Slam that has eluded him when he wore down Russia's Teymuraz Gabashvili 7-6, 7-6, 6-3 in the first round of the US Open on Tuesday.
A summary of Tuesday's action at the US Open.
It was like old times at Arthur Ashe Stadium as US Open fans gave Andre Agassi a rousing ovation as the former champion was honoured before Monday's opening night programme at Flushing Meadows.