For Hyderabad, KXIP encounter is the last game where they can avail the services of Warner before he leaves home for Australia's World Cup preparations alongside Steven Smith and Marcus Stoinis.
Mumbai Indians enter the match high on confidence following successive victories over holders Chennai Super Kings and last edition's finalists Sunrisers Hyderabad.
Smith was handed a one-year ban along with his then deputy David Warner exactly a year ago for their roles in the ball-tampering scandal in South Africa.
Virat Kohli-led Royal Challengers Bangalore have won only three games out of 10 in IPL-12 so far.
Sunrsiers' middle-order has hardly been tested and when the opportunity came against Mumbai Indians, the likes of Vijay Shankar, Manish Pandey, Deepak Hooda and Yusuf Pathan fell flat.
The home team's bowlers will be wary of Chris Gayle's power-hitting.
While Kings XI's biggest star Chris Gayle scored a 47-ball 79 in the Jaipur match, his Jamaican compatriot Andre Russell also looked in blistering touch for KKR in the match against Sunriserrs Hyderabad. Their rivalry will be one of the sub plots of Wednesday's clash in Kolkata.
With a debate raging over the run out, it remains to be seen how Ashwin and Co. start afresh in what will be their first away match of the season.
Chennai Super Kings will aim to maintain their pole position with a victory over a struggling Kings XI Punjab
The two teams are languishing at the bottom half of the table and need a win to keep alive their remote Play-off chances.
Seeking home comforts after multiple reverses at the Ferozshah Kotla, Delhi Capitals will be desperate to buck the trend when they take on a rejuvenated Kings XI Punjab in the Indian Premier League, in Delhi, on Saturday.
Focus will now be on how Rabada would fare against the likes of Chris Gayle, Lokesh Rahul, Mayank Agarwal and David Miller.
RCB have been inconsistent in their first six games in IPL-12, with both their bowling and batting faltering on many occasions.
KXIP are riding a roller-coaster ride, having to endure a controversy involving their captain Ravichandran Ashwin who 'Mankaded' Rajasthan Royals batsman Jos Buttler in their first match, an act which was legal but criticised by some as against the 'Spirit of Cricket'.
List of players released by IPL teams ahead of next month's auction for 2020 season:
The R Ashwin-led Kings XI slipped to the fifth spot after suffering back-to-back losses against Mumbai Indians and Royal Challengers Bangalore respectively. Overall, the hosts have registered four wins from eight matches this season.
Rajneesh Gupta presents statistical summary of Kings XI Punjab and much more.
India Test regulars like Cheteswar Pujara and Ishant Sharma have also thrown their hat into the ring with base prices of Rs 50 and Rs 75 lakh respectively.