The American slumped to a 7-6, 2-6, 6-4 defeat by Frenchman Fabrice Santoro in the first round of the Lyon Grand Prix.
Roger Federer survived a scratchy performance to beat Marcos Baghdatis 7-6, 7-5 to reach the quarter-finals.
Second seed Rafael Nadal beat fellow-Spaniard Juan Carlos Ferrero, while Andy Roddick got past France's Richard Gasquet at the Pacific Life Open.
World number two Roger Federer comfortably beat Cypriot Marcos Baghdatis 6-4, 6-3 on Saturday to set up a meeting with American Mardy Fish in the final of the Cincinnati Masters. Fish had earlier pulled off a surprise turnaround win over fellow American Andy Roddick to claim a 4-6, 7-6, 6-1 victory and advance to his third Masters series final.
The victory sent Federer into Saturday's semi-finals against fourth seed Nikolay Davydenko of Russia, who beat 10th seed Tommy Haas 6-3 6-3 6-4.
Croat Ivan Ljubicic celebrated his first Masters 1000 title after upsetting seventh-seeded American Andy Roddick 7-6, 7-6 in the final of the Indian Wells ATP tournament on Sunday.
Andy Roddick's body finally gave up on him when he limped out of the Shanghai Masters after retiring in the first set of his second-round match against Swiss Stanislas Wawrinka on Tuesday.
Andy Roddick completed round-robin play at the Masters Cup an unbeaten 3-0 blasting his way past Guillermo Coria 7-6, 6-3.
Injury-stricken Rafael Nadal and Wimbledon finalist Andy Roddick will be among the big names forced to miss the Davis Cup World Group quarter-finals starting on Friday.
Second seed Andy Roddick crashed out in the first round of the Rome Masters, losing 7-6, 6-1 to Guillermo Canas.
Frances Tiafoe, Taylor Fritz, Tommy Paul and Coco Gauff all advanced to the third round of the US Open on Wednesday to keep home hopes alive.
Juan Martin Del Potro spoiled Andy Roddick's return to the tour after a month-long hiatus by upsetting the top seed and world number five 3-6, 7-5, 7-6 to win the Washington Classic on Sunday.
The United States will rely on the same quartet that won last year's Davis Cup when they face France in next month's quarter-final, captain Patrick McEnroe said on Thursday. Andy Roddick, James Blake, Bob Bryan and Mike Bryan will participate in their record tenth consecutive tie together, said McEnroe.
Andy Roddick's right shoulder survived a bruising examination by Spaniard Feliciano Lopez on Tuesday as the American opened his grasscourt season with a 7-6, 6-7, 6-4 victory in the second round at Queen's Club.
The top two seeds survived second-round scares at the Madrid Masters.
French Open champion Justine Henin enjoyed a swift 60-minute workout to overcome Russia's Vera Dushevina to enter the third round.
World number eight Andy Roddick and 18th-ranked Sam Querrey will represent the United States in a first-round Davis Cup tie against Chile next month, captain Jim Courier said on Thursday.
Top seed Roger Federer withstood a few anxious moments before defeating Spain's Feliciano Lopez in four sets to book a quarter-final berth against old foe Andy Roddick at the U.S. Open on Monday.
Top seed Roger Federer beat Germany's Bjorn Phau 7-5, 6-0, 6-4 to open his Australian Open defence.
World number one Roger Federer will return to suburban Melbourne to defend his Kooyong Classic invitational tournament title in January.
Murray faces Andy Roddick in his first Wimbledon semi-final on Friday with the British press devoting endless column inches to his chances of becoming the first men's home champion since Fred Perry in 1936.
Fernando Verdasco upset top seed Andy Roddick 3-6, 6-4, 6-4 to win the San Jose Open on Sunday and snap a 15-match losing streak against top 10-ranked players.
World number two Roger Federer set up an Australian Open semi-final showdown with American Andy Roddick after he demolished Argentine Juan Martin del Potro 6-3, 6-0, 6-0 in the quarter-finals on Tuesday. Roddick got the better of defending champion Novak Djokovic, who threw in the towel in another quarter-final because of 'cramping and soreness in the whole body'.
The Indian pair was drawn in a relatively easy bottom half in the men's doubles tennis at the Athens Games.
World number two Andy Roddick will lead the U.S. against Spain in the Davis Cup final next month.
Andy Roddick is the man no one wants to play golf with.
The American teenager beat compatriot Paul Goldstein in the San Jose Open first round on Monday.
US captain Patrick McEnroe said the duo would be joined by the world's top-ranked doubles pair, Bob and Mike Bryan. John Isner and Sam Querrey will travel with the team as practice partners.
James Blake fought off two match-points to beat Paul-Henri Mathieu 7-6, 6-7, 6-3, 3-6, 7-5 and lifted the United States to a 2-0 lead over France in their Davis Cup quarter-final on Friday. Earlier in the day, Andy Roddick gave the US a 1-0 lead in a close 6-4, 7-6, 7-6 victory over Michael Llodra.
Eubanks is into his first Grand Slam quarter-final after beating fifth seed Stefanos Tsitsipas on Monday
As Coco Gauff ponders a fortnight without tennis following her first-round loss at Wimbledon, she might be tempted to phone one of the sport's most accomplished coaches.