The duo require success at the U.S. Open not only to sate their own ambitions but to gain the upper hand in their personal rivalry.
The world No. 1 was beaten by unseeded Russian Lina Krasnoroutskaya in the third round of the Canadian Open.
The Belgian whipped Lindsay Davenport to reach the final of the Acura Classic. She meets Justine Henin-Hardenne.
The 2000 and 2001 champion will be gunning for revenge when play starts on Centre Court at 1400 GMT.\n\n
Belgian duo Kim Clijsters and Justine Henin-Hardenne once again fell victim to the raw power of Williams sisters Venus and Serena.
The defending Wimbledon champion avenged her French Open defeat with a 6-3, 6-2 victory.
The French Open champion was forced to retire during the Ordina Open final because of a wrist injury.
The Belgian duo set up a rematch of their French Open final after winning their semi-finals at the Ordina Open. \n\n
Henin maiden Grand Slam success was the result of sublime claycourt tennis and the way she has transformed her once-unhappy private life.
The fourth-seeded Belgian will meet compatriot Kim Clijsters in the women's French Open final.
Clijsters completed her inexorable progress to Sunday's final with a 6-3, 6-2 win over Sugiyama.
Justine Henin-Hardenne survived three match points to overcome Kim Clijsters 6-4, 4-6, 7-5 in a thrilling all-Belgian German Open final
The 21-year-old will play crowd favourite fourth seed Kim Clijsters in Thursday's semi-finals.
A hobbling Monica Seles suffered her earliest exit at a grand slam tournament when she was knocked out 6-7 7-5 6-3 by Czech qualifier Klara Koukalova at the Australian Open.
Tennis star Serena Williams on Wednesday dropped a big hint that she could be pregnant with her first baby as she posted a picture of Snapchat with the caption "20 weeks".
In an interview last month after a World Tennis Tour event at the Greenbrier in West Virginia, they said they had not yet decided whether they were finished competing. Playing almost exclusively with each other throughout their 25-year careers, the Bryans captured a professional era record 119 titles, including 16 Grand Slam wins, 39 ATP Masters 1000s and the ATP Finals title four times.
However, Jelena Dokic was upset by qualifier Maria Vento-Kabchi in the Bank of the West Classic.
"I generally don't play with pain, but this is a Grand Slam and I just wanted to win," said the American.\n\n
The Belgian rallied from the brink of defeat to beat Amelie Mauresmo in the final of the Romes Masters.
Serena Williams beat crowd favourite Kim Clijsters in one of the greatest comebacks in tennis history.
Following Iga Swiatek's victory over Coco Gauff in the final, here's a list of French Open women's singles champions:
Sofia Kenin lifted her first Grand Slam trophy in Melbourne at the start of the year and then added a WTA title in Lyon, days before the circuit came to a halt due to the novel coronavirus pandemic.
Summary of sports events and persons who made news on Sunday
Serena Williams has given birth to a baby girl, the first child for the former world number one tennis player, her coach Patrick Mouratoglou said on Twitter on Friday.
Mike Bryan of the United States claimed his 17th Grand Slam men's doubles title when he and Jack Sock beat Raven Klaasen and Michael Venus 6-3, 6-7(7), 6-3, 5-7, 7-5 in a thrilling Wimbledon final on Saturday.
'All the superlatives and beautiful words that you can think of she deserves it.'
Women's Tennis Association Chief Executive Steve Simon has defended the wildcard entry awarded to former world number one Maria Sharapova.
Germany's Angelique Kerber, who will try to prevent Serena Williams winning an eighth Wimbledon title on Saturday, never went away but she too is making a comeback of sorts.
IMAGES from Day 4 of the Wimbledon Champions at the All England Lawn Tennis and Croquet Club, London, on Thursday