Sevilla were on course for a place in the King's Cup semi-finals after crushing Deportivo Coruna 3-0 at the Riazor in their last-eight first leg match on Wednesday.
Holders Barcelona booked a Champions League last 16 berth with a 2-1 win at Dynamo Kiev on Wednesday and were joined by Group F rivals Inter Milan, who sealed their passage with a 2-0 home defeat of Rubin Kazan.
Juventus and Bayern Munich square off in a Champions League match on Tuesday which will end with one of the illustrious pair suffering the same fate as Liverpool and making an early exit from the tournament.
Five-times winners Liverpool were knocked out of the Champions League in the group stages despite a 1-0 win at Debrecen on Tuesday while Fiorentina and Arsenal qualified for the last 16.
Holders Barcelona were knocked out of the King's Cup on Wednesday when they won a thrilling last-16 second-leg clash at Sevilla 1-0 but were eliminated on the away goals rule after the tie ended 2-2 on aggregate.
Holders Barcelona suffered a stunning 2-1 home defeat by Russia's Rubin Kazan while Liverpool lost by the same score to Olympique Lyon at Anfield on a night of high drama and late goals in the Champions League on Tuesday.
Arsenal manager Arsene Wenger used to dream about Luis Suarez, the signing that got away, and he will be hoping the Uruguayan striker doesn't give him nightmares when holders Barcelona visit in the Champions League on Tuesday.
Holders Barcelona reached the King's Cup semi-finals with a 2-0 win over Espanyol on Thursday to overcome a first-leg deficit on a night when new signing Philippe Coutinho made his debut.
Chelsea, Liverpool and Manchester United all avoided each other in the Champions League quarter-final draw.
Chelsea coach Jose Mourinho said his team's comfortable 2-0 victory over Levski Sofia on Tuesday, felt more like a friendly than a Champions League match.
A repeat of the 2014 Champions League final between Real Madrid and Atletico Madrid is still possible after Friday's semi-final draw.
Chelsea will try to succeed where Manchester United failed when they meet Reading the Premier League on Saturday.
Real Madrid face Olympique Lyon, Dynamo Kiev and Steaua Bucharest in Group E of the Champions League.
Barcelona went out of the Champions League in the first knockout phase on the away goals rule despite a 1-0 win over Liverpool.
Holders Barcelona must beat Levski Sofia to make sure of avoiding a shock exit from the UEFA Champions League.
'I just do what the team needs me to do, just keep playing well and score more goals,' said the Chelsea striker after scoring in the 1-0 win over Barcelona in the Champions League.
Santiago Solari got off to the perfect start as Real Madrid's interim coach when his side thrashed Melilla 4-0 in the Copa del Rey on Wednesday.
With a comfortable first-leg advantage, Zinedine Zidane rested much of his first team, making 10 changes from the line-up that struggled to a disappointing draw at Celta Vigo on Sunday to fall 16 points behind league leaders Barcelona.
Twenty-three-times Cup winners Athletic Bilbao were dumped out in sensational circumstances by tiny island side SD Formentera, who sneaked a 1-0 win at San Mames with a header by Alvaro Muniz deep in stoppage-time to reach the last 16 for the first time with a 2-1 aggregate victory.
Holders Barcelona will play Premier League leaders Arsenal in the last 16 of the Champions League, 10 years after the sides faced each other in the final, following Monday's draw for the first knockout stage.
Last year's finalists Juventus will face-off against Bundesliga champs Bayern.
News of all that's transpired on and off the football field
Holders Barcelona will face fellow Spaniards Atletico Madrid, runners-up two seasons ago, in the Champions League quarter-finals following the draw in Nyon on Friday.
Real Madrid are on the verge of reaching the King's Cup quarter-finals after winning 3-0 at Numancia on Thursday while holders Barcelona still have work to do after being held to a 1-1 draw at Celta Vigo.
Atletico Madrid coach Diego Simeone praised his team's spirit after knocking holders Barcelona out of the Champions League.
News of all that's transpired on and off the football field
King's Cup holders Barcelona beat Real Sociedad 1-0 in their quarter-final first leg to end a nine-and-a-half year barren spell at home of the Basque side while Atletico Madrid crushed Eibar on Thursday.
Lionel Messi and Luis Suarez were on target as holders Barcelona thrashed Real Sociedad 5-2 to reach the King's Cup semi-finals for the seventh successive year with a 6-2 aggregate victory on Thursday.
Guardiola is on track to lead Bayern to a third consecutive Bundesliga title but his three-year spell there will ultimately be judged on whether he can win Europe's elite club competition with them.
Holders Barcelona cruised into the King's Cup quarter-finals when a side missing several regulars beat city rivals Espanyol 2-0, with Munir El Haddadi netting both goals in a thumping 6-1 aggregate success on Wednesday.
Real Madrid crashed out of the King's Cup quarter-finals 4-3 on aggregate after being held to a 2-2 draw at Celta Vigo on Wednesday in another major setback for the stuttering European champions.
Barcelona defender Gerard Pique fears his side's shock elimination from the Champions League could disturb their bid to retain the La Liga title as they host Valencia on Sunday looking for a first win in four league games.
Heavyweight trio Manchester City, Manchester United and Chelsea kept up their 100 per cent starts to the Premier League season this weekend.
Lionel Messi, Luis Suarez and Neymar were all on target as holders Barcelona beat Athletic Bilbao 3-1 on Wednesday to overturn a deficit from the first leg and advance to the quarter-finals of the King's Cup.
Atletico Madrid are not seeking revenge for their 2014 Champions League final defeat but instead want to write a new chapter in the club's history with their first European Cup after getting past Bayern Munich.
Holders Barcelona crashed out of the Champions League after being stifled by a brilliantly well-organised Atletico Madrid.
In-form Borussia Moenchengladbach struck three times in 14 minutes in the second half to floor champions Bayern Munich 3-1 on Saturday and inflict their first Bundesliga defeat of the season.
Spain became the first country to have five teams in the Champions League group stage in one season after Valencia squeezed past Monaco .
Manchester United ended their one-year Champions League hiatus in emphatic style when Wayne Rooney struck a hat-trick in a 4-0 destruction of Club Bruges that sent the three-times winners through 7-1 on aggregate on Wednesday.
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