Former midfielder Fletcher made 342 appearances in all competitions with the club, the majority of them under Ferguson. He was also recently coach of the under-18 squad.
The 44-year-old inherits a team in crisis, sitting seventh in the Premier League table -- a whopping 17 points behind leaders Arsenal -- and eliminated from both domestic cups.
Gabriel Martinelli scored his first hat-trick for Arsenal as the Premier League leaders beat second-tier strugglers Portsmouth 4-1 to reach the FA Cup fourth round.
While there are suggestions that Ruben Amorim's comments at Sunday's press conference triggered his axing, the verdict was clear given his under-performance in the hot seat.
Arsenal's Premier League title prospects were enhanced without them even kicking a ball on Wednesday as their closest challengers Manchester City and Aston Villa both dropped points.
West Bromwich Albion have signed Scotland midfielder Darren Fletcher on a free transfer from Manchester United, the English Premier League clubs said on Monday.
New Manchester United manager Louis van Gaal has given England striker Wayne Rooney the role of team captain and made Scotland midfielder Darren Fletcher his vice-captain.
City's Guardiola defends Mendy after COVID protocol breach.
Manchester United midfielder Darren Fletcher has been ruled out for the rest of the season after having surgery to resolve a bowel condition, the Premier League leaders said.
There will be no panic buying in the January transfer window despite serious injuries to key players, Manchester United manager Alex Ferguson said on Friday.
Manchester United midfielder Darren Fletcher is taking an extended break from football due to health problems, the Premier League champions said on Tuesday.
Striker Dimitar Berbatov scored a clinical first goal as Manchester United sauntered to a 3-0 victory against promoted Newcastle United in their Premier League opener at Old Trafford on Monday.
Salomon Rondon dented 10-man Manchester United's top-four challenge with a sharp second-half strike to maintain West Bromwich Albion's Premier League revival on Sunday. The 26-year-old Venezuela striker controlled Sebastien Pocognoli's cross from the left before burying the ball into the left corner on 67 minutes against an increasingly toothless United, who had lost Juan Mata to a second yellow card on 26 minutes. The Spain international was booked for not retreating and blocking a quickly-taken free kick before receiving his marching orders two minutes later for kicking Darren Fletcher's shin in a clumsy tackle. United's first league defeat at The Hawthorns since 1984 kept them sixth in the table, three points behind Manchester City in fourth, while West Brom climbed to 11th with a third win in four league games.
Everton scored twice in stoppage time to snatch an unlikely 3-3 home Premier League draw with Manchester United on Saturday in a game that Wayne Rooney missed to spare him from potential crowd abuse.
Manchester United's Darren Fletcher and Barcelona pair Eric Abidal and Daniel Alves will miss the Champions League final after UEFA said on Monday there were no grounds for overturning their suspensions.
Manchester United have asked UEFA to overturn the controversial red card that will keep midfielder Darren Fletcher out of the Champions League final, British newspapers reported on Friday.
Chelsea gave their new Brazilian coach Luiz Felipe Scolari the perfect start on Sunday with a stunning 4-0 victory over Portsmouth in their opening Premier League match at Stamford Bridge.
Armed men raided the home of Manchester United midfielder Darren Fletcher while the player was away in Italy, threatening his fiancee with a knife and stealing jewellery.
Substitute Michael Owen struck in the sixth minute of stoppage-time to earn Manchester United a 4-3 Premier League win over Manchester City in one of the all-time great derby matches on Sunday.
Substitute Michael Owen struck in the sixth minute of injury time to earn Manchester United a 4-3 Premier League win over Manchester City in one of the most dramatic derbies for years on Sunday. Three times United led -- through Wayne Rooney and two Darren Fletcher headers -- but three times City fought back with a goal from Gareth Barry and two from Craig Bellamy, his second coming in the 90th minute, before Owen decided it.
Wayne Rooney scored twice again as Manchester United cruised into the quarter-finals of the Champions League after a 4-0 win over a feeble AC Milan sent them through 7-2 on aggregate on Wednesday.
Manchester United wasted the chance to close on the Premier League leaders when a sloppy second half cost them in a 1-1 draw at Everton on Saturday.
Scotland flew out to Georgia on Monday boosted by the news that Manchester United midfielder Darren Fletcher may have recovered enough from injury to start in their Euro 2008 Group B qualifier.
Manchester United were held to a 2-2 draw by J-League champions Urawa Reds in a friendly match at Saitama Stadium on Tuesday.
The eagerly-awaited FA Cup fifth-round clash between England's two top teams turned out to be a one-sided affair.
Premier League leaders Manchester United beat Charlton Athletic 2-0 to stay six points clear of Chelsea.
, sources said the English champions have offered 30 million euros ($39 million) to bring the former Arsenal captain back to the Premier League.
Manchester United beat Chelsea 1-0 to end the champions' 40-match unbeaten run in the English Premier League.
Ten-man Manchester United held on to beat Middlesbrough 1-0 at the Riverside on Sunday.
Chelsea midfielder Cesc Fabregas was sent off in bizarre circumstances as the below-par Premier League champions, playing with 10 men for over an hour, slumped 3-0 at West Bromwich Albion.
Manchester United manager Louis Van Gaal has slammed Juan Mata for receiving a red card, saying that the midfielder had 'damaged' the club's chances of victory.
Darren Fletcher is lucky to be playing after chronic bowel disease threatened to end his career, the Manchester United midfielder said on Wednesday.
Manchester United's footballers and their wives and girlfriends have a blast at this year's Christmas party.
Holders Arsenal's long unbeaten run in the FA Cup continued but they were frustrated by stubborn Championship leaders Hull City on Saturday, drawing 0-0 in a dreary fifth-round tie at the Emirates Stadium.
'It was shambolic ... so bad' 'United didn't need a new philosophy, they had one for 20-odd years that worked'
Manchester United's winless run continued but they gave under-fire coach Louis van Gaal crumbs of cheer with a committed display in an entertaining 0-0 draw with Chelsea while Arsenal went top of the table on Monday.
Manchester United can challenge for the league title after recovering from their worst start to a Premier League season and rediscovering the art of winning ugly, according to their captain Wayne Rooney.
Liverpool flop Fabio Borini finally got Sunderland's English Premier League campaign up and running with a derby winner against bitter rivals Newcastle.