Liverpool and champions Manchester City drew 0-0 at Anfield while Chelsea and Arsenal enjoyed comfortable away wins. City are top on goal difference from Liverpool and Chelsea with Arsenal two points behind.
Chelsea maintained their iron grip on top spot with a 2-1 win at Crystal Palace while Southampton recorded one of the biggest victories in Premier League history when they crushed a woeful Sunderland side 8-0 at St Mary'son Saturday.
Three matches into the Premier League season following a stunning title success by 5,000-1 outsiders LeicesterCity, the table already has a more familiar look.
Liverpool had won each of their previous four home leagues games in which they conceded first and 12 minutes later they had turned another match on its head as Roberto Firmino's trickery set up Mane to give the hosts the lead at the second attempt.
Manchester City's eight point advantage after 11 games is leading to talk of the Premier League title race being over in November, but as Manchester United manager Jose Mourinho noted - English football has a habit of throwing up surprises.
Christian Pulisic scored his 10th goal for the United States before being substituted after picking up a knock in a 1-1 draw with Chile in a friendly in Houston on Tuesday.
Manchester City tore Arsenal apart for the second time in five days on Thursday, beating them 3-0 on a freezing night at The Emirates to restore their 16-point lead as they close in on the Premier League title.
Here are five talking points from the weekend's Premier League action:
A clash between supposedly the two most expensive lineups in history overseen by two of the most decorated coaches will end the phoney war and ignite the Premier League season for real when Manchester United host Manchester City on Saturday.
Real Madrid are hoping the fit-again Cristiano Ronaldo can lead them into the Champions League final although strike partner Karim Benzema remains a doubt for Wednesday's return match with Manchester City.
Manchester City overcame a spirited Bournemouth side 3-1 on Saturday to maintain their unbeaten streak and extend their lead at the top of the English Premier League to five points.
Liverpool reached the Champions League semi-finals for the first time in 10 years as Mohamed Salah and Roberto Firmino struck decisive blows to secure a 2-1 win over Manchester City on Tuesday that completed a 5-1 aggregate victory.
Manchester City look to take an important step in their transformation into one of the world's leading clubs on Tuesday by reaching the Champions League semi-finals for the first time.
Chelsea's on-loan Brazilian international Alexandre Pato scored on his debut to help push pathetic Aston Villa to the verge of inevitable relegation with a seventh successive Premier League defeat on Saturday. Pato, the former Milan starlet who has been kicking his heels since joining from Corinthians two months ago, came on as a 25th-minute substitute and was immediately involved in the move which led to Ruben Loftus-Cheek netting his first league goal.
Attack is the best form of defence for Manchester City boss Pep Guardiola.
'If you take a point or even lose, it's not ideal but there are still almost 30 games to go so this result won't be the deciding factor in who wins the title'
If Manchester United are to claim a seventh successive Premier League victory and condemn leaders Chelsea to a first home league defeat of the season their manager Louis van Gaal must solve another complex injury puzzle.
Lionel Messi says he is retiring from international soccer after Argentina lost to Chile in Copa America final.
Chile upset favourites Argentina with a penalty shootout victory in the Copa America final at MetLife Stadium on Sunday to retain their title in the world's oldest continental soccer competition.
Leicester City will be wary of a reality check when the Premier League front-runners visit Arsenal on Sunday before Tottenham Hotspur's burgeoning title ambitions come under scrutiny at Manchester City.
Manchester City made the most of a case of mistaken identity and kept alive their faint title hopes thanks to a much-needed 3-0 victory over 10-man West Bromwich Albion in the Premier League on Saturday.
Manchester City displayed champions' swagger as they roared clear at the top with a 5-0 trouncing of Burnley but it was drama which engulfed their neighbours Manchester United and Jose Mourinho that dominated the Premier League agenda on Saturday.
Chelsea's Diego Costa continued his stunning start to life in the Premier League with a hat-trick in a 4-2 comeback win over Swansea City on Saturday that left champions Manchester City staring up the table after a 2-2 draw at Arsenal.
Irresistible Chelsea go into the Christmas round of fixtures knowing they can end the year by re-writing the record books.
Real Madrid got their Champions League title defence off to a strong start on Wednesday by convincingly beating AS Roma 3-0 at home with goals from Isco, Gareth Bale and a stoppage-time strike from returning striker Mariano Diaz.
Leicester City's Premier League title defence got off to a terrible start as they were beaten 2-1 at promoted Hull City, who shrugged off an injury crisis to shock the champions on the opening day of the new season on Saturday
Manchester City are about to find out whether Raheem Sterling has the ability to justify his enormous price tag or is just another over-rated young English footballer motivated purely by his bank balance.
Rediff.com brings a preview of the main matches coming up this weekend in the English Premier League.
Liverpool players hail Juergen Klopp impact after defeating City.
London clubs' erratic start to the Premier League season improved with victories for Chelsea, Tottenham Hotspur and Arsenal on Saturday but Manchester sides continued to make the running, with City and United the top two.
Chelsea ticked off three more points in their Premier League title quest with a 2-1 victory over Manchester City on Wednesday but Tottenham Hotspur's Houdini-like 3-1 win at Swansea means the race is far from over.
Following is a match by match look at the English Premier League's weekend fixtures:
Hazard collected 53 percent of the vote making him a comfortable winner, while he and Terry's Chelsea team mates Cesc Fabregas, Branislav Ivanovic and goalkeeper Thibaut Courtois also featured in the top 10.
images from the UEFA Champions League matches played across Europe on Wednesday
Monaco swept into the Champions League quarter-finals and left Manchester City to pick up the pieces of another failed European campaign after a 3-1 victory on Wednesday sent them through on away goals.
Liverpool scored a stunning 3-2 win over bottom side Queens Park Rangers with four goals coming in a frenzied seven-minute finale at Loftus Road as the drama continued in the Premier League on Sunday.
With the 3-0 loss, Chelsea and the Gaffer have now matched the club's worst records -- Mourinho suffered his joint-heaviest defeat as a Premier League manager, while, for the first time in 17 years, the Blues have failed to record a win in either of their opening league games
The victory puts the pressure back on title rivals Liverpool who are at Cardiff City on Sunday and trail by a point with each side having played 34 games.
Zlatan Ibrahimovic noted this week in his own inimitably self-regarding fashion that he had taken just three months to conquer England.
The much-anticipated clash between Liverpool and ManchesterCity at Anfield on Saturday looks like a knockout to determine who can challenge Chelsea for the Premier League title.