In a hard-fought title round, the Indian double Olympics medallist stayed strong in the key moments to win 21-9, 11-21, 21-15 against the 22-year-old reigning Asian Championships gold medallist.
The 41-year-old Bopanna, ranked 40 in the world, is not defending any points this year at the Roland Garros.
The duo of Rohan Bopanna and Denis Shapovalov crashed out of the semi-finals of the men's doubles event at the ongoing St Petersburg Open St Petersburg on Saturday.
Yuki Bhambri advanced to the men's singles second round after a hard-fought win over Moldovian Radu Albot in the US Open qualifiers in New York.
The Indians will now lock horns with top seeds Ivan Dodig of Croatia and Brazilian Marcelo Melo in the summit clash of the of the ATP 250 event.
Veteran Indian tennis player Rohan Bopanna and his Croatian partner Franko Skugor advanced to the third round of the French Open with a straight sets win over Americans Frances Tiafo and Nicholas Monroe.
Sumit Nagal has been dropped from the five-member Indian Davis Cup team for the World Group 1 play-off tie against Denmark in New Delhi next month.
'Your attitude and spirit to win every game is something that inspires everyone'
Rafael Nadal is no stranger to being out of action for months due to injuries taking a toll on his body but when the Spaniard pulled out from a virtual reality tennis match that would have been contested using a game console - it raised a few eyebrows. The claycourt king had been expected to take on gamer DjMariio as part of a virtual Madrid Open charity event - but ended up being a no show on Monday.
With the main draw of the Asian Badminton Championships set to get underway from Wednesday, the struggling Indian shuttlers face an uphill task.
Sindhu will face either Spain's three-time world champion Carolina Marin or Tokyo Olympics silver medallist Tai Tzu Ying of Chinese Taipei next.
Double Olympic medallist PV Sindhu, who is returning from an ankle injury, begins her campaign against former World Champion Carolina Marin of Spain in the first round of Malaysia Open.
Naomi Osaka has sacked her second coach in seven months, splitting with Jermaine Jenkins
Naomi Osaka joins other sports figures in speaking out against racism and police violence, including basketball great Michael Jordan and Formula One champion Lewis Hamilton.
However, Ramkumar Ramanathan and Ankita Raina's campaign ended in the first round itself.
'I am not too disappointed. I feel like he had to come up with the goods, and it did feel like to some extent it was on my racquet, I just came up against somebody who was, on the day, a bit better when it really mattered'
Rohan Bopanna and Ramkumar Ramanathan blew away their chances in the must-win doubles match as India lost the World Group I tie to Finland after conceding an unassailable 0-3 lead, in Espoo on Saturday.
In a setback to India's medal chances in tennis at the Tokyo Olympics, Rohan Bopanna and Divij Sharan missed the cut for men's doubles, which also rules out the country's presence in the mixed team competition -- its best chance for a podium finish.
P V Sindhu hopes to continue her rich vein of form in upcoming events, including the Birmingham Commonwealth Games, after winning the Singapore Open on Sunday.
Star shuttlers, including P V Sindhu, will chase individual gold medals but doubles would also under the spotlight as India would aim to retain the mixed team title and continue their consistent run at the Commonwealth Games.
India's doubles specialist Rohan Bopanna, who failed to make the cut for the Tokyo Olympics along with Divij Sharan because of their low combined rank, on Monday accused All India Tennis Association (AITA) of misleading everyone by claiming it had changed the combination by pairing him with Sumit Nagal for a shot at qualification.
Argentina's experimental line-up proved too strong for an outclassed Singapore in their international friendly on Tuesday, with the South Americans swatting aside their hosts 6-0 and the opening five goals coming from first-time scorers.
Naomi Osaka has witnessed a huge change in her career after claiming a maiden Grand Slam title in 2018, but the rising star of women's tennis will not be changing her quirky personality in media appearances that has endeared her to so many.
Angelique Kerber produced a polished display to claim her second straight win at the WTA Finals with a 6-4, 6-2 victory over Simona Halep on Tuesday, the world number one virtually booking a spot in the semi-finals of the elite eight-woman event.
American Stephens stayed calm and saw off an increasingly agitated Angelique Kerber in the winner-takes-all night match to complete round-robin play with a spotless 3-0 record after she wrapped up a 6-3, 6-3 victory against the German.
Audacious coups by Andy Murray and Angelique Kerber have transformed the tennis landscape and they will begin 2017 eyeing the kind of domination that few would have thought possible at the start of a seismic year.
World No 2 Rafael Nadal brushed aside American Jared Donaldson 6-1, 6-1 and will next face Diego Schwartzman after the Argentine beat Roberto Carballes 6-3, 6-1.
The top-seeded Serb, who had not dropped a set in four matches since the round of 16 at the Australian Open in January, looked out-of-sorts throughout the 98-minute contest.