Manchester United won away for the first time this season when they beat Arsenal 2-1 at the Emirates Stadium on Saturday to climb to fourth in the Premier League table.
A goal by Sergio Aguero gave Manchester City a 1-0 victory against neighbours Manchester United, who played with 10 men for more than 50 minutes on Sunday.
West Ham United maintained their impressive start to the season when they beat champions Manchester City 2-1 at Upton Park on Saturday to consolidate their place in the top four of the Premier League.
Arsenal maintained their challenge for a first trophy in nine seasons when they beat Liverpool 2-0 at the Emirates Stadium to open up a five-point lead at the top of the Premier League on Saturday.
Zlatan Ibrahimovic and Cristiano Ronaldo come face-to-face next month when Sweden meet Portugal in a World Cup playoff and they sharpened their claws with six goals between them on a thrilling night of Champions League action on Wednesday.
Wolfsburg shock Real Madrid 2-0 to crown big European night.
Manchester City started their Premier League campaign in scintillating fashion on Monday with a stylish 4-0 win at home to 10-man Newcastle United that will ring alarm bells for the rest of their title rivals.
There will be plenty of tension in the air in North London on Wednesday when out-of-sorts Arsenal face Borussia Dortmund seeking to qualify from the Champions League group stage for the 15th successive season.
Champions League holders Real Madrid will face former European champions Liverpool, FC Basel and debutants Ludogorets of Bulgaria following the group stage draw on Thursday.
Arsenal beat Fulham 2-0 at the Emirates and Manchester City beat Cardiff City 4-2 at the Etihad before Liverpool could only manage a 2-2 draw at Anfield having trailed 2-0.
Cristiano Ronaldo renewed his personal battle with Lionel Messi by scoring his 71st Champions League goal, putting him three behind the Argentine's newly-set record, in Real Madrid's 1-0 win at FC Basel on Wednesday.
Barcelona forward Lionel Messi equalled the Champions League scoring record of 71 goals when he struck for the second time in the 76th minute of Wednesday's Group F match at Ajax Amsterdam.
Photos from the Champions League matches played across Europe on Tuesday.