It was a day of role reversal as Jose Mourinho's often cautious Chelsea thumped Everton 6-3 in a thriller on Saturday while champions Manchester City's attacking talents were blunted in a shock 1-0 home defeat by Stoke City.
After Sunday's crushing 4-2 derby defeat at Manchester United, even a top four finish and a place in next season's Champions League is no longer a certainty.
Michael Laudrup became the latest manager to fall victim to a jinx that has now claimed five of the last six men who led their clubs to victory in the League Cup final when the Dane parted company with Swansea City on Tuesday.
Chelsea ended their slump with a win over Arsenal while seemingly invincible Manchester City lost their 100 per cent record to West Ham United on a day of contrasting fortunes for the Premier League title favourites on Saturday.
Jose Mourinho's wretched week ended on a high note as Manchester United's big guns Zlatan Ibrahimovic and Paul Pogba finally began firing, both finding the target in a 3-1 win at dismal Swansea City on Sunday. Mourinho watched from the stands at the Liberty Stadium following his touchline ban imposed by the Football Association on Wednesday and was buoyed to see Ibrahimovic score twice -- his first league goals in eight weeks -- and Pogba net a superb volley. United, vastly improved after their midweek Europa League defeat at Fenerbahce, went ahead with a 15th minute strike from Pogba worthy of his 89 million pounds price tag before Ibrahimovic ended his goal drought with a sharp first-half double in the space of 12 minutes.
Dimitri Payet struck a brace for the Hammers against a tired Newcastle, whose players had to trudge the last mile to West Ham United's stadium after their team coach became stuck in London's rush-hour traffic before Monday's Premier League fixture.
Manchester City maintained their perfect start to the season with a 2-0 victory over promoted Watford as champions Chelsea suffered a shock 2-1 home defeat by Crystal Palace on Saturday.
English clubs took their spending on players for the season soaring past 1 billion pounds on Monday, but the biggest signing on transfer deadline day was that of a manager as Manchester City confirmed Pep Guardiola will take over this summer.
CrystalPalace striker Marouane Chamakh ended an 11-game barren streak to help them beat fellow Premier League strugglers West Ham United 1-0 in manager Tony Pulis's home debut on Tuesday.
Arsenal ended Leicester City's brief stay at the top of the Premier League on Sunday despite being held to a 0-0 draw at Stoke City after Manchester United's Wayne Rooney struck late for a 1-0 win at Liverpool.
Chelsea overpowered West Ham United and Manchester City outclassed West Bromwich Albion as the Premier League title rivals signalled their intent at the start of a hectic holiday programme on Friday.
Southampton suffered an embarrassing 1-0 League Cup quarter-final defeat at third tier Sheffield United on Tuesday while Chelsea powered through with a 3-1 win at Derby County.
Seasonal cheer has been scarce for Louis van Gaal after a six-match winless sequence for his Manchester United side intensified rumours that he will be sacked and Stoke City are unlikely to be offering any solace on Saturday.
Newcastle United's Papiss Cisse struck twice in a 2-1 victory against English Premier League leaders Chelsea.
Champions Manchester City galvanised their pursuit of Premier League leaders Chelsea on Sunday with an emphatic 3-0 victory over a Southampton side who have surprisingly come between the leading title protagonists.
Goals from Victor Moses and Daniel Sturridge eased Liverpool through a tricky FA Cup fourth round tie at Championship (second division) Bournemouth on Saturday although they had to work hard for a 2-0 victory.
Barely a game into the Indian Super League and Mumbai City FC have been dealt a massive blow with skipper Syed Rahim Nabi ruled out for upto three weeks due to an ankle injury sustained during the team's opening match against Atletico de Kolkata.
Eden Hazard and Fernando Torres applied the gloss to a workmanlike 2-0 victory at Hull City that lifted Chelsea ominously to the top of the Premier League on Saturday.
Leicester City continued to do their best Houdini impression on Saturday as they escaped the Premier League drop zone for the first time since November while Manchester City went up to second spot with a thrilling win.
Manchester United's early season problems were compounded by a humiliating 4-0 loss to third-tier Milton Keynes Dons in the League Cup second round on Tuesday leaving new manager Louis van Gaal still looking for his first win.
Manchester United's calamitous week hit rock bottom as Bournemouth famously consigned them to a 2-1 defeat on Sunday and, to rub salt into the wounds, neighbours Manchester City moved back to the top of the English Premier League.
Liverpool's hopes of winning their first title in 24 years suffered a huge setback when they lost 2-0 at home to Chelsea and Manchester City took advantage with a 2-0 victory at Crystal Palace.
Manchester United consolidated their fourth place, on 22 points, after first-half goals from Chris Smalling and Wayne Rooney and a brilliant, morale-boosting strike from Robin van Persie after the break sealed a 3-0 victory over Hull City.
Goals rained in for Manchester City and Manchester United but Juergen Klopp's first game as Liverpool manager was solid rather than spectacular as they drew 0-0 at Tottenham Hotspur in the Premier League.
After an indifferent Premier League start and without an away win this season, Manchester United manager Louis van Gaal's belief that his side can still win the Premier League is misplaced, says former club captain Gary Neville.
UEFA president Michel Platini has repeated his call for the "triple punishment" of red card, penalty and suspension to be dropped following two controversial dismissals in the Champions League this week.
Chelsea scrambled a stoppage-time winner to snatch a 1-0 victory over Everton on Saturday, showing their Premier League title mettle by claiming three points when they looked on course to suffer another damaging blow.
Arsenal delivered a brutal lesson in fast-paced Premier League football to beat Liverpool 4-1 on Saturday, maintaining their faint title aspirations and almost certainly dashing their opponents' hopes of a top-four finish.
FA Cup added another incredible chapter to its proud heritage on Saturday as Chelsea and Manchester City were humbled by supposed inferiors.
A leave vote means the future of Britain's financial services industry is now hanging in the balance.
Stevan Jovetic and Jesus Navas scored their first goals for ManchesterCity who avenged last season's shock FA Cup final defeat by Wigan Athletic with a 5-0 victory in the League Cup third round on Tuesday.
Steven Gerrard's future at Liverpool may be in doubt but the captain turned back the clock to score in a 3-1 victory at bottom side Leicester City in the Premier League on Tuesday.
Barcelona look well set to wrap up the La Liga title.
In England, the celebrations went on at Leicester City as they marked their fairytale Premier League success with another win while champions Juventus' long unbeaten streak in Italy came to an end.
United Kingdom will go to the polls on Thursday. This election is being dubbed the most unpredictable of all time.
Liverpool took a giant step towards their first title in 24 years with a 3-2 win at a plucky Norwich City on Sunday, opening up a five point lead over second-placed Chelsea with three matches remaining.
The Hong Kong Football Association were left red-faced and out of pocket after only managing to sell half the tickets for Tuesday's glamour friendly against Argentina to mark their centenary.
Arsenal and Swedish legend Freddie Ljungberg, who will be plying his trade for ISL franchise Mumbai City FC, said he wanted to play in the new football league to inspire youngsters and help them.
Harry Kane's magical season continued on Saturday as he celebrated his first senior England call-up with his first Premier League hat-trick.
An Eden Hazard hat-trick swept Chelsea back to the top of the Premier League on Saturday when they beat Newcastle United 3-0 at Stamford Bridge after previous leaders Arsenal were thrashed 5-1 at Liverpool.