Kei Nishikori swept aside Rafael Nadal in the quarter-finals of the Rogers Cup.
Former World No 1 Ana Ivanovic was upset 7-5, 6-4 by 42nd-ranked Karolina Pliskova of the Czech Republic in the second round of the US Open on Thursday.
Croatian ninth seed Marin Cilic reached the Wimbledon quarter-finals for the third year running after Kei Nishikori quit with a rib injury midway through their fourth round match on Monday.
US Open champions Marin Cilic and Serena Williams kicked off their China Open campaigns with straight sets victories against battling underdogs on Monday, but Rafael Nadal suffered defeat in a rare doubles outing on his return from injury.