Paris St Germain will play Borussia Dortmund and Barcelona were pitted against an unpredictable Napoli, while Chelsea were drawn against Bayern Munich. City, who will be at home in the second leg, have yet to beat the Spanish side with two draws and two defeats in their previous four meetings.
Chelsea manager Jose Mourinho returned to Spain with an ultra-cautious approach as his team earned a 0-0 draw with surprise Champions League semi-finalists Atletico Madrid in a first leg lacking in excitement on Tuesday.
Atletico Madrid produced an inspired display of counter-attacking football to beat Chelsea 3-1 in the UEFA Champions League semi-final second leg in London on Wednesday and set up an all-Spanish final against city rivals Real.
Dudu Omagbemi and Konstantinos Katsouranis scored in each half as FC Pune City beat Atletico de Kolkata 3-1 and snapped the league leaders' unbeaten run in the Hero Indian Super League in Kolkata on Friday.
Barcelona must to wait to confirm a place in the Champions League last 16 after dropping points for the first time in Group D in an absorbing 0-0 draw at Olympiakos Piraeus on Tuesday.
France and Spain will step up security ahead of the Champions League quarter-finals in Madrid and Paris on Tuesday and Wednesday nights, top officials said, as Islamic State threats cast a shadow over Europe's top club soccer tournament.
A breathtaking individual goal from Saul Niguez put Atletico Madrid in the box seat in their Champions League semi-final against Bayern Munich with a 1-0 victory in a tense first leg on Wednesday.
Barcelona were held to a 1-1 home draw, a result which leaves the champions three points behind league leaders Sevilla.
Chelsea have signed Spain World Cup striker Diego Costa from Atletico Madrid, the Stamford Bridge club said in a statement on Tuesday.
Chelsea forward Samuel Eto'o is out of Tuesday's Champions League semi-final first leg at Atletico Madrid because of injury.
The result meant Real moved up to third place, one point ahead of Valencia and three behind leaders Barcelona.
Barcelona, Atletico Madrid and Real Madrid resume a nail-biting La Liga title race on Saturday after all notched up victories on Wednesday. Leaders Barcelona, who ended a four-game winless streak by hammering Deportivo La Coruna 8-0 away from home, host struggling Sporting Gijon on Saturday. Atletico battled to a 1-0 win at Athletic Bilbao to stay level on 79 points with Barcelona, who top the table with a superior head-to-head record and host Malaga. Real stayed one point behind their title rivals after beating Villarreal 3-0 and are expected to be without top scorer Cristiano Ronaldo for their visit to struggling neighbours Rayo Vallecano. The Portuguese forward was unable to finish the game against Villarreal after suffering cramp in stoppage time but eased concerns he had suffered a serious injury.
La Liga is set for one of its most thrilling finishes when Barcelona host leaders Atletico Madrid in a winner-takes-all showdown at the Nou Camp on the final day of the campaign on Saturday.
Barcelona moved ever closer towards a successful defence of their La Liga title after nearest challengers Atletico Madrid suffered a shock late collapse at struggling Sporting Gijon to lose 2-1 on Saturday.
A rousing 2-1 La Liga victory at Real Madrid on Saturday may suggest otherwise, but Atletico Madrid are still rebuilding after losing several key players in the close season, coach Diego Simeone said on Monday.
Sevilla claimed their second King's Cup triumph in four years when Diego Capel's early strike and a late breakaway goal from Jesus Navas fired them to a 2-0 win over Atletico Madrid on Wednesday.
Luka Modric pulled one back for Zinedine Zidane's shellshocked side with a brilliant strike from distance early in the second half before substitute Vinicius Jr reduced the deficit to one goal.
Atletico Madrid striker Radamel Falcao scored two superb goals and Diego added a late third to seal a commanding 3-0 victory over Athletic Bilbao in the all-Spanish Europa League final on Wednesday.
Defending champions Chennaiyin FC and Atletico de Kolkata played out a highly-entertaining 2-2 draw in their campaign opening match in the Indian Super League football tournament in Kolkata on Sunday.
News of all that's transpired on and off the football field
Cristiano Ronaldo struck midway through the first half as leaders Real Madrid won 1-0 at Malaga in La Liga on Saturday, while Atletico Madrid stayed hot on their heels after Diego Costa netted in a 1-0 victory over Espanyol.
With Real Madrid facing an injury crisis ahead of Wednesday's Champions League clash with Atletico Madrid attention will be on talisman Cristiano Ronaldo to lead them through but James Rodriguez may hold the key.
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Atletico Madrid's La Liga title challenge took a nosedive when they slumped to a shock 3-0 defeat at Osasuna on Sunday, leaving Real Madrid three points clear at the top.
Joao Miranda and new signing Mario Mandzukic led Atletico Madrid to a 2-1 home win in La Liga on Saturday as visitors Eibar were unable to cope with the aerial threat of the champions.
The 22-year-old Spain striker has ruled out a move away from Atletico Madrid.
Antoine Griezmann scored twice off the bench as Atletico Madrid sealed a place in the King's Cup quarter-finals with a 3-0 win at home to Rayo Vallecano on Thursday while Valencia also advanced with victory by the same scoreline at Granada.
Atletico Madrid striker Mario Mandzukic's early goal secured a 1-0 win over Real Madrid and a 2-1 aggregate success to clinch the Spanish Super Cup and gain some revenge for last season's Champions League final defeat.
Spain and Liverpool legend Luis Garcia believes that Indian football can touch global heights if the players are given exposure to different leagues abroad and nourish young talents and coaches methodically.
Joaquin, 37, became the oldest scorer in a Seville top-flight derby when he rose to head home at the near post in the 79th minute, shortly after the visitors had had midfielder Roque Mesa sent off for two bookings.
A quickfire Arda Turan double, including an acrobatic bicycle kick, fired Atletico Madrid to a 3-1 home win over Espanyol in La Liga on Sunday and lifted the Europa League semi-finalists up to seventh.
Christmas came early to the 'City of Joy' as the inaugural Indian Super League champions Atletico de Kolkata returned home to a hero's welcome.
'I expect a brave Napoli that plays from the back and presses high, that doesn't speculate, has a lot of individual talent, it's a big game and it's a great team, current champions of Italy.'
Simeone's side leapfrogged Real Sociedad into fourth on 42 points, while Sevilla stayed third in the standings on 46 after beating Las Palmas 1-0, also on Sunday, thanks to a late strike from substitute Joaquin Correa
Barcelona and Atletico Madrid dropped their first points of the season on Saturday, missing the chance to equal the record for the best-ever La Liga start.
Photos from the UEFA Champions League last 16 first leg-matches played on Wednesday
Atletico Madrid kept pace with leaders Barcelona and restored their five-point lead over third-placed city rivals Real when Diego Costa and David Villa each scored a penalty in a 2-1 win at Granada in La Liga on Thursday.
Atletico Madrid surrendered top spot in La Liga to Barcelona when they were held to a 0-0 draw at home to 10-man Sevilla in a fiercely contested La Liga clash on Sunday.
Real Madrid's stuttering run continued as they were held 1-1 at home by La Liga minnows Eibar on Sunday, drawing a fourth consecutive game in all competitions for the first time in more than a decade.
Atletico Madrid got their La Liga campaign up and running in less than convincing fashion when Antoine Griezmann's deflected free kick secured an edgy 1-0 win at home to promoted Las Palmas on Saturday.
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