Frenchman Adrian Mannarino also quit at two sets apiece against eight-times champion Roger Federer after sliding over on Centre Court and injuring his knee.
Since 2003, one of Roger Federer, Novak Djokovic, Rafael Nadal or Andy Murray have won the title at Wimbledon, with the Swiss leading the way with eight titles.
"There have been moments for optimism - plenty. And on the men's side, not as much."
Petra Martic kept her composure to advance to the Round of 16
Big-serving Canadian Milos Raonic fired 19 aces to topple Sam Querrey 6-4, 6-4 and set up a second-round clash with either Dan Evans or Russian 10th seed Andrey Rublev.
Playing in his first competitive singles match on the ATP Tour since August 5, the 20-times Grand Slam champion showed no signs of rust in his second round win against Lithuanian qualifier Ricardas Berankis.
The 21-year-old German became only the fifth active player to win at least three Masters 1000 titles -- joining the 'big four' of Rafael Nadal, Roger Federer, Novak Djokovic and Andy Murray.
High-level intelligence collection will no longer be the preserve of government agencies alone, says Pranjal Sharma.
'You have to feel like the whole world working normally again and travelling normally before tennis would go back to especially the major competitions'
IMAGES from English Premier League matches played on Sunday.
'I'd say there's very little chance I'd play singles during the grass (season). Potentially doubles, but I'm not trying to get ready for singles. I've only just started moving now'
Britain will attempt to win the Davis Cup for the first time in 79 years this weekend when they take on Belgium in Ghent, although if they do succeed the Scottish town of Dunblane could argue its name should be enscribed on the trophy.
List of French Open men's singles champions:
